AH 11110 HYDROCHLORIDE
- Product Name
- AH 11110 HYDROCHLORIDE
- CAS No.
- 179388-65-9
- Chemical Name
- AH 11110 HYDROCHLORIDE
- Synonyms
- AH 11110;AH11110HCl;AH 11110 HYDROCHLORIDE;AH 11110 >98% (HPLC), solid;4-IMINO-1-(2-PHENYLPHENOXY)-4-PIPERIDINEBUTAN-2-OL HYDROCHLORIDE;1-[BIPHENYL-2-YLOXY]-4-IMINO-4-PIPERIDIN-1-YL-BUTAN-2-OL HYDROCHLORIDE
- CBNumber
- CB1475539
- Molecular Formula
- C21H27ClN2O2
- Formula Weight
- 374.91
- MOL File
- 179388-65-9.mol
AH 11110 HYDROCHLORIDE Property
- storage temp.
- −20°C
- solubility
- H2O: ~2.5 mg/mL, soluble
- form
- solid
- color
- slightly yellow
- Water Solubility
- Soluble to 25 mM in water
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- A3477
- Product name
- AH 11110
- Purity
- >98% (HPLC), solid
- Packaging
- 50mg
- Price
- $761
- Updated
- 2023/01/07
- Product number
- 0998
- Product name
- AH11110hydrochloride
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $73
- Updated
- 2021/12/16
- Product number
- 0998
- Product name
- AH11110hydrochloride
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $306
- Updated
- 2021/12/16
- Product number
- A434503
- Product name
- AH11110Hydrochloride
- Packaging
- 5mg
- Price
- $360
- Updated
- 2021/12/16
- Product number
- 254568
- Product name
- AH 11110 hydrochloride
- Packaging
- 10mg
- Price
- $423
- Updated
- 2021/12/16
AH 11110 HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
AH 11110 Hydrochloride is an α1B-adrenoceptor selective drug. AH 11110 Hydrochloride has been shown to interact with α1-adrenoceptors as well as α2-adrenoceptors.
Biological Activity
A subtype-selective ligand for the α 1B -adrenoceptor. The pK i values for binding to rat fibroblast cell membranes expressing α 1B (hamster), α 1A (bovine) and α 1D (rat) are 7.1, 5.59, and 5.68 respectively. Appears to be non-selective between α 1 subtypes and α 2 receptors in smooth muscle preparations.
References
[1]. erami c, zhang h, ho jg, et al. alpha(1)-adrenoceptor stimulation directly induces growth of vascular wall in vivo. am j physiol heart circ physiol, 2002, 283(4): h1577-1587.
[2]. eltze m, könig h, ullrich b, et al. failure of ah11110a to functionally discriminate between alpha(1)-adrenoceptor subtypes a, b and d or between alpha(1)- and alpha(2)-adrenoceptors. eur j pharmacol, 2001, 415(2-3): 265-276.
AH 11110 HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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