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NFAT Transcription Factor Regulator

Product Name
NFAT Transcription Factor Regulator
CAS No.
245747-71-1
Chemical Name
NFAT Transcription Factor Regulator
Synonyms
NFAT Transcription Factor Regulator;NFAT Transcription Factor Regulator-1;NFAT Transcription Factor Regulator-1, 10 mM in DMSO;NFAT Transcription Factor Regulator 1,NFAT Transcription Factor Regulator1;N-(4-(5-(Difluoromethoxy)-3-(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)-3-fluoroisonicotinamide;4-Pyridinecarboxamide, N-[4-[5-(difluoromethoxy)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-
CBNumber
CB14797086
Molecular Formula
C17H10F6N4O2
Formula Weight
416.28
MOL File
245747-71-1.mol
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NFAT Transcription Factor Regulator Property

Boiling point:
408.4±45.0 °C(Predicted)
Density 
1.53±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : ≥ 150 mg/mL (360.33 mM);Water : < 0.1 mg/mL (insoluble)
form 
Solid
pka
9.85±0.70(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0063874
Product name
NFATTranscriptionFactorRegulator-1
Purity
99.37%
Packaging
5mg
Price
$175
Updated
2021/12/16
ChemScene
Product number
CS-0063874
Product name
NFATTranscriptionFactorRegulator-1
Purity
99.37%
Packaging
10mg
Price
$295
Updated
2021/12/16
ChemScene
Product number
CS-0063874
Product name
NFATTranscriptionFactorRegulator-1
Purity
99.37%
Packaging
50mg
Price
$880
Updated
2021/12/16
Biorbyt Ltd
Product number
orb572897
Product name
NFAT Transcription Factor Regulator
Packaging
100mg
Price
$1431.4
Updated
2021/12/16
ChemScene
Product number
CS-0063874
Product name
NFATTranscriptionFactorRegulator-1
Purity
99.37%
Packaging
100mg
Price
$1500
Updated
2021/12/16
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NFAT Transcription Factor Regulator Chemical Properties,Usage,Production

Biological Activity

NFAT Transcription Factor Regulator-1 is an inhibitor of IL-2 synthesis with IC50 of 182 nM.

in vitro

NFAT Transcription Factor Regulator-1 (compound example 19) inhibits IL-2 synthesis with an IC 50 of 182 nM. NFAT Transcription Factor Regulator-1 inhibits human and rat PBMC proliferation with IC 50 s of 82 and 146 nM, respectively. NFAT Transcription Factor Regulator-1 is able to inhibit IL-4 and IL-5 production in human T-cell lines with similar potency to its effects on IL -2 release.

target

IL-2

< span> 182 nM (IC 50 )

NFAT Transcription Factor Regulator Preparation Products And Raw materials

Raw materials

Preparation Products

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NFAT Transcription Factor Regulator Suppliers

China 17 United States 4 Global 21
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9804
Advantage
58
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
5998
Advantage
55
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29764
Advantage
68
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32159
Advantage
58
DC Chemicals
Tel
021-58447131 13564518121
Email
sales@dcchemicals.com
Country
China
ProdList
9409
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Shanghai hongqu biomedical technology co. LTD
Tel
88888888888
Email
hongquchem@qq.com
Country
China
ProdList
5132
Advantage
58
cjbscvictory
Tel
13348960310 13348960310
Email
3003867561@qq.com
Country
China
ProdList
10524
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
62072
Advantage
58

245747-71-1, NFAT Transcription Factor RegulatorRelated Search:


  • NFAT Transcription Factor Regulator
  • NFAT Transcription Factor Regulator-1
  • 4-Pyridinecarboxamide, N-[4-[5-(difluoromethoxy)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-
  • NFAT Transcription Factor Regulator 1,NFAT Transcription Factor Regulator1
  • N-(4-(5-(Difluoromethoxy)-3-(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)-3-fluoroisonicotinamide
  • NFAT Transcription Factor Regulator-1, 10 mM in DMSO
  • 245747-71-1