5,?8,?11,?14-?Tetraoxa-?2-?azaheptadecanedioic acid, 1-?[(1α,?8α,?9β)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl] ester

Product Name: 5,?8,?11,?14-?Tetraoxa-?2-?azaheptadecanedioic acid, 1-?[(1α,?8α,?9β)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl] ester
CAS No.: 1881221-47-1
Chemical Name: 5,?8,?11,?14-?Tetraoxa-?2-?azaheptadecanedioic acid, 1-?[(1α,?8α,?9β)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl] ester
Synonyms: BCN-PEG4-acid;BCN-endo-PEG4-COOH;BCN-PEG4-ACID (ENDO);1-[(1α,8α,9β)-Bicyclo[6.1.0]non-4-yn-9-ylmethyl] 5,8,11,14-tetraoxa-2-azaheptade;1-((1R,8S)-bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid;rel-1-((1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid;5,?8,?11,?14-?Tetraoxa-?2-?azaheptadecanedioic acid, 1-?[(1α,?8α,?9β)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl] ester
CBNumber: CB14809471
Molecular Formula: C22H35NO8
Formula Weight: 441.52
MOL File: 1881221-47-1.mol

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5,?8,?11,?14-?Tetraoxa-?2-?azaheptadecanedioic acid, 1-?[(1α,?8α,?9β)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl] ester Property

Boiling point:: 608.2±55.0 °C(Predicted)
Density: 1.20±0.1 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
form: Viscous Liquid
pka: 4.28±0.10(Predicted)
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0119067
Product name: BCN-PEG4-acid
Packaging: 50mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0119067
Product name: BCN-PEG4-acid
Packaging: 250mg
Price: $950
Updated: 2021/12/16

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5,?8,?11,?14-?Tetraoxa-?2-?azaheptadecanedioic acid, 1-?[(1α,?8α,?9β)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl] ester Chemical Properties,Usage,Production

Uses

endo-BCN-PEG4-acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. endo-BCN-PEG4-acid is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC 50

Cleavable Linker

References

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268

5,?8,?11,?14-?Tetraoxa-?2-?azaheptadecanedioic acid, 1-?[(1α,?8α,?9β)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl] ester Preparation Products And Raw materials

Raw materials

Preparation Products

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5,?8,?11,?14-?Tetraoxa-?2-?azaheptadecanedioic acid, 1-?[(1α,?8α,?9β)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl] ester Suppliers

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View Lastest Price from 5,?8,?11,?14-?Tetraoxa-?2-?azaheptadecanedioic acid, 1-?[(1α,?8α,?9β)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl] ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: endo BCN-PEG4-acid 1881221-47-1
Price: US $0.00/mg
Min. Order: 50mg
Purity: >95.00%
Supply Ability: 250mg
Release date: 2024-03-20

1881221-47-1, 5,?8,?11,?14-?Tetraoxa-?2-?azaheptadecanedioic acid, 1-?[(1α,?8α,?9β)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl] esterRelated Search:

BCN-endo-PEG4-COOH

BCN-PEG4-ACID (ENDO)

BCN-PEG4-acid

rel-1-((1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid

5,?8,?11,?14-?Tetraoxa-?2-?azaheptadecanedioic acid, 1-?[(1α,?8α,?9β)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl] ester

1-((1R,8S)-bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid

1-[(1α,8α,9β)-Bicyclo[6.1.0]non-4-yn-9-ylmethyl] 5,8,11,14-tetraoxa-2-azaheptade

1881221-47-1

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