BSJ-03-123

Product Name: BSJ-03-123
CAS No.: 2361493-16-3
Chemical Name: BSJ-03-123
Synonyms: BSJ-03-123;Inhibitor,CDK,PROTACs,Cyclin dependent kinase,inhibit,BSJ03123,BSJ 03 123;N-(2-(2-(2-(2-(4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)ethoxy)ethoxy)ethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide;Acetamide, N-[2-[2-[2-[2-[4-[6-[(6-acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinyl]ethoxy]ethoxy]ethoxy]ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-
CBNumber: CB14818336
Molecular Formula: C47H56N10O11
Formula Weight: 937.01
MOL File: 2361493-16-3.mol

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BSJ-03-123 Property

Density: 1.375±0.06 g/cm3(Predicted)
storage temp.: 4°C, protect from light
solubility: DMSO : 100 mg/mL (106.72 mM; ultrasonic and adjust pH to 3 with HCl)
pka: 10.68±0.40(Predicted)
form: Solid
color: White to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Tocris

Product number: 6921
Product name: BSJ-03-123
Purity: ≥98%(HPLC)
Packaging: 5
Price: $352
Updated: 2021/12/16

ChemScene

Product number: CS-0087154
Product name: BSJ-03-123
Purity: 99.45%
Packaging: 5mg
Price: $250
Updated: 2021/12/16

ChemScene

Product number: CS-0087154
Product name: BSJ-03-123
Purity: 99.45%
Packaging: 10mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0087154
Product name: BSJ-03-123
Purity: 99.45%
Packaging: 100mg
Price: $1200
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573021
Product name: BSJ-03-123
Purity: >98%
Packaging: 100mg
Price: $1283.5
Updated: 2021/12/16

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BSJ-03-123 Chemical Properties,Usage,Production

Uses

BSJ-03-123 is a PROTAC connected by ligands for Cereblon and CDK as a potent and novel CDK6-selective small-molecule degrader.

IC 50

CDK6; Cereblon

storage

Store at -20°C

References

[1] Brand M, et al. Homolog-Selective Degradation as a Strategy to Probe the Function of CDK6 in AML. Cell Chem Biol. 2019 Feb 21;26(2):300-306.e9. DOI:10.1016/j.chembiol.2018.11.006

BSJ-03-123 Preparation Products And Raw materials

Raw materials

Preparation Products

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BSJ-03-123 Suppliers

China 38 United States 6 Global 44

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
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BOC Sciences

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Email: info@bocsci.com
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Shanghai YuanYe Biotechnology Co., Ltd.

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Aikon International Limited

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Jilin Province Woda Biotechnology Co., Ltd.

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TargetMol Chemicals Inc.

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InvivoChem

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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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Shanghai hongqu biomedical technology co. LTD

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2361493-16-3, BSJ-03-123Related Search:

BSJ-03-123

Acetamide, N-[2-[2-[2-[2-[4-[6-[(6-acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinyl]ethoxy]ethoxy]ethoxy]ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-

Inhibitor,CDK,PROTACs,Cyclin dependent kinase,inhibit,BSJ03123,BSJ 03 123

N-(2-(2-(2-(2-(4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)ethoxy)ethoxy)ethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide

2361493-16-3

C47H56N10O11