Metizolam

Metizolam Property

Melting point:

153-154 °C

Boiling point:

527.2±60.0 °C(Predicted)

Density 

1.46±0.1 g/cm3(Predicted)

storage temp. 

-10 to -25°C

solubility 

DMF: 15mg/mL; DMSO: 15mg/mL; DMSO:PBS (pH 7.2) (1:3): 0.25mg/mL

form 

A crystalline solid

pka

1.99±0.40(Predicted)

InChI

InChI=1S/C16H13ClN4S/c1-2-10-7-12-15(11-5-3-4-6-13(11)17)18-8-14-20-19-9-21(14)16(12)22-10/h3-7,9H,2,8H2,1H3

InChIKey

NQSSWDKQLVBUQN-UHFFFAOYSA-N

SMILES

N12C=NN=C1CN=C(C1=CC=CC=C1Cl)C1C=C(CC)SC=12

Safety

WGK Germany 

WGK 2

Storage Class

3 - Flammable liquids

Hazard Classifications

Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Flam. Liq. 2

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Metizolam Chemical Properties,Usage,Production

Uses

Metizolam can be used as reactant/reagent in in preparation of thienylazole and thienotriazolodiazepine compounds as cholecystokinin antagonists. It can also be used in biological study of platelet-activating factor antagonist.