A-381393
- Product Name
- A-381393
- CAS No.
- 726174-00-1
- Chemical Name
- A-381393
- Synonyms
- A-381393;A-381393, 10 mM in DMSO;A-381393;A 381393;A381393;inhibit,Dopamine Receptor,A381393,Inhibitor,A-381393,A 381393;1H-Benzimidazole, 2-[[4-(3,4-dimethylphenyl)-1-piperazinyl]methyl]-;2-{[4-(3,4-dimethylphenyl)piperazin-1-yl]methyl}-1H-1,3-benzodiazole;2-((4-(3,4-Dimethylphenyl)piperazin-1-yl)methyl)-1H-benzo[d]imidazole
- CBNumber
- CB14844423
- Molecular Formula
- C20H24N4
- Formula Weight
- 320.43
- MOL File
- 726174-00-1.mol
A-381393 Property
- storage temp.
- Store at -20°C
- solubility
- DMSO:51.67(Max Conc. mg/mL);161.25(Max Conc. mM)
- form
- Solid
- color
- Light yellow to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- Axon2944
- Product name
- A 381393
- Packaging
- 10mg
- Price
- $137.5
- Updated
- 2026/05/19
- Product number
- Axon2944
- Product name
- A 381393
- Packaging
- 50mg
- Price
- $467.5
- Updated
- 2026/05/19
- Product number
- S89748
- Product name
- A 381393
- Purity
- 98%
- Packaging
- 25MG
- Price
- $100
- Updated
- 2026/05/27
- Product number
- S89748
- Product name
- A 381393
- Purity
- 98%
- Packaging
- 100MG
- Price
- $260
- Updated
- 2026/05/27
- Product number
- S89748
- Product name
- A 381393
- Purity
- 98%
- Packaging
- 1G
- Price
- $815
- Updated
- 2026/05/27
A-381393 Chemical Properties,Usage,Production
Uses
A-381393 is a potent, selective, brain penetrate dopamine D4 receptor antagonist, with Kis of 1.5, 1.9 and 1.6 nM for human dopamine D4.4, D4.2, and D4.7 receptor, respectively, >2700-fold selectivity over D1, D2, D3 and D5 dopamine receptors. A-381393 shows moderate affinity for 5-HT2A (Ki, 370 nM)[1].
IC 50
D3 Receptor; D4 Receptor
References
[1] Nakane M, et al. 2-[4-(3,4-Dimethylphenyl)piperazin-1-ylmethyl]-1H benzoimidazole (A-381393), a selective dopamine D4 receptor antagonist. Neuropharmacology. 2005 Jul;49(1):112-21. DOI:10.1016/j.neuropharm.2005.02.004
A-381393 Preparation Products And Raw materials
Raw materials
Preparation Products
A-381393 Suppliers
- Tel
- 1-631-485-4226; 16314854226
- info@bocsci.com
- Country
- United States
- ProdList
- 12952
- Advantage
- 65
- Tel
- 021-52996696，15000506266 15000506266
- Fax
- +86-21-52996696
- Country
- China
- ProdList
- 4846
- Advantage
- 55
- Tel
- 021-65675885 18964387627
- Fax
- 021-65675885
- info@efebio.com
- Country
- China
- ProdList
- 9803
- Advantage
- 58
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 89686
- Advantage
- 60
- Tel
- 15076683720
- Fax
- 022-23754520
- klq@cw-bio.com
- Country
- China
- ProdList
- 9710
- Advantage
- 55
- Tel
- 177-54423994 17754423994
- Fax
- QQ:2853530913
- 2853530910@QQ.com
- Country
- China
- ProdList
- 7999
- Advantage
- 62
- Tel
- QQ：65489617 19372819560
- Fax
- 21-5161 9052
- Sales@ATKchemical.com
- Country
- China
- ProdList
- 9625
- Advantage
- 58
- Tel
- 0-2022843681 15618226720
- Fax
- +86-21-51601218
- chaolaichem@foxmail.com
- Country
- China
- ProdList
- 9798
- Advantage
- 58
- Tel
- +1-708-310-1919 +1-13798911105
- Fax
- 708-557-7486
- sales@invivochem.cn
- Country
- United States
- ProdList
- 6391
- Advantage
- 58
- Tel
- +86-0371-86658258 +8613203830695
- Fax
- 0371-86658258
- laboratory@coreychem.com
- Country
- China
- ProdList
- 30225
- Advantage
- 58