ChemicalBook > CAS DataBase List > Marilixibat chloride
Marilixibat chloride
- Product Name
- Marilixibat chloride
- CAS No.
- 228113-66-4
- Chemical Name
- Marilixibat chloride
- Synonyms
- SHP625;SHP-625;HP-625);SHP 625;Livmarli;Lopixibat;Maralixibat;Maralixibat?chloride;Marilixibat chloride;Lopixibat chloride (LUM-001
- CBNumber
- CB14844993
- Molecular Formula
- C40H56ClN3O4S
- Formula Weight
- 710.42
- MOL File
- 228113-66-4.mol
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Marilixibat chloride Property
- storage temp.
- Store at -20°C
- form
- Solid
- color
- White to light yellow
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Marilixibat chloride Chemical Properties,Usage,Production
Description
Marilixibat chloride is an oral small-molecule ileal bile acid transporter (IBAT) inhibitor developed by Mirum Pharmaceuticals and approved by the USFDA for cholestatic pruritus in patients with Alagille syndrome (ALGS). IBAT facilitates reabsorption of bile acids from the ileum and is a key facilitator of bile acid enterohepatic recirculation. Similar to surgical interruption of enterohepatic recirculation, it was shown that inhibition of IBAT with 22 reduced pruritis in patients with ALGS.
Marilixibat chloride Preparation Products And Raw materials
Raw materials
Preparation Products
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