(S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5- yl)methyl)formamide

Product Name: (S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5- yl)methyl)formamide
CAS No.: 168828-65-7
Chemical Name: (S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5- yl)methyl)formamide
Synonyms: Linezolid-7;Demethyl linezolid;Linezolid Impurity 86;(T)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)formamide;(S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5- yl)methyl)formamide;Formamide, N-[[(5S)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-;Linezolid impurity 20/(S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5- yl)methyl)formamide
CBNumber: CB14845329
Molecular Formula: C15H18FN3O4
Formula Weight: 323.32
MOL File: 168828-65-7.mol

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(S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5- yl)methyl)formamide Property

Boiling point:: 580.6±50.0 °C(Predicted)
Density: 1.332±0.06 g/cm3(Predicted)
pka: 15.40±0.23(Predicted)

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Hazard and Precautionary Statements (GHS)

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(S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5- yl)methyl)formamide Chemical Properties,Usage,Production

Uses

Demethyl linezolid is a impurity of linezolid. Demethyl linezolid is a useful antimicrobial agent extracted from patent WO1995007271A1, example 9, effective against a number of human and veterinary pathogens[1].

in vivo

Demethyl linezolid inhibits the activity of Staphylococcus aureus bacteria in mice with an ED₅₀ of 4.4 mg/kg by oral intubation^[1].

References

[1] Michael R, et, al. Substituted oxazine and thiazine oxazolidinone antimicrobials. WO1995007271A1

(S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5- yl)methyl)formamide Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5- yl)methyl)formamide Suppliers

China 15 India 1 United States 1 Global 17

Wuxi Zhongkun Biochemical Technology Co., Ltd.

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Shanghai Payne Pharmaceutical Technology Co.Ltd

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Wuxi Helen Biotechnology Co., Ltd.,

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Guangzhou Juntang Technology Co., Ltd

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168828-65-7, (S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5- yl)methyl)formamideRelated Search:

DEMETON S

(S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5- yl)methyl)formamide

(T)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)formamide

Linezolid Impurity 86

Linezolid-7

Linezolid impurity 20/(S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5- yl)methyl)formamide

Formamide, N-[[(5S)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-

Demethyl linezolid

168828-65-7

C15H18FN3O4