4,6-DIAMINO-5-(FORMYLAMINO)-PYRIMIDINE

Product Name: 4,6-DIAMINO-5-(FORMYLAMINO)-PYRIMIDINE
CAS No.: 5122-36-1
Chemical Name: 4,6-DIAMINO-5-(FORMYLAMINO)-PYRIMIDINE
Synonyms: FAPy-adenine;DIAMINO-15N2);DIAMINO-15N2, 98%);Adenosine Impurity 33;FAPYADENINE(FORMYL-13C;4,6-diamino-5-n-formamidopyrimidine;4,6-DIAMONO-5-(FORMYLAMINO)PYRIMIDNE;4,6-DIAMINO-5-(FORMYLAMINO)-PYRIMIDINE;N-(4,6-Diaminopyrimidin-5-yl)formamide;4,6 diamino-5-formamide pyrimidine HCl
CBNumber: CB1484939
Molecular Formula: C5H7N5O
Formula Weight: 153.14
MOL File: 5122-36-1.mol

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4,6-DIAMINO-5-(FORMYLAMINO)-PYRIMIDINE Property

Melting point:: 224-226 °C
Boiling point:: 536.1±50.0 °C(Predicted)
Density: 1.575±0.06 g/cm3(Predicted)
storage temp.: −20°C
pka: 12.35±0.70(Predicted)
form: Solid
color: Off-white to light yellow

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0059551
Product name: FAPy-adenine
Purity: 99.93%
Packaging: 10mg
Price: $100
Updated: 2021/12/16

ChemScene

Product number: CS-0059551
Product name: FAPy-adenine
Purity: 99.93%
Packaging: 25mg
Price: $180
Updated: 2021/12/16

ChemScene

Product number: CS-0059551
Product name: FAPy-adenine
Purity: 99.93%
Packaging: 50mg
Price: $280
Updated: 2021/12/16

ChemScene

Product number: CS-0059551
Product name: FAPy-adenine
Purity: 99.93%
Packaging: 100mg
Price: $420
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0310353
Product name: 4,6-DIAMINO-5-(FORMYLAMINO)-PYRIMIDINE
Purity: 95.00%
Packaging: 5MG
Price: $501.22
Updated: 2021/12/16

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4,6-DIAMINO-5-(FORMYLAMINO)-PYRIMIDINE Chemical Properties,Usage,Production

Uses

FAPy-adenine is an oxidized DNA base. Fapy-adenine shows an increased trend levels in the Alzheimer's disease brain. Oxidized nucleosides are biochemical markers for tumors, aging, and neurodegenerative diseases[1][2][3].

Definition

ChEBI: A member of the class of aminopyrimidines that is 4,6-diaminopyrimidine bearing an additional formamido substituent at position 5. A DNA lesion formed when DNA exposed to ionising radiation.

in vivo

The nuclear DNA damage by oxygen-derived radicals is increased in Alzheimer's disease and support the concept that the brain is under increased oxidative stress in Alzheimer's disease^[1].

IC 50

Human Endogenous Metabolite

References

[1] Gabbita SP, et al. Increased nuclear DNA oxidation in the brain in Alzheimer's disease. DOI:10.1046/j.1471-4159.1998.71052034.x
[2] Cysewski P, et al. Theoretical description of the coding potential of diamino-5-formamidopyrimidines. Z Naturforsch C J Biosci. 1999 Mar-Apr;54(3-4):239-45. DOI:10.1515/znc-1999-3-414
[3] Lee SH, et al. A rapid and sensitive method for quantitation of nucleosides in human urine using liquid chromatography/mass spectrometry with direct urine injection. Rapid Commun Mass Spectrom. 2004;18(9):973-7. DOI:10.1046/j.1471-4159.1998.71052034.x

4,6-DIAMINO-5-(FORMYLAMINO)-PYRIMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4,6-DIAMINO-5-(FORMYLAMINO)-PYRIMIDINE Suppliers

China 31 Switzerland 1 United Kingdom 2 United States 12 Global 46

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Alfa Chemistry

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View Lastest Price from 4,6-DIAMINO-5-(FORMYLAMINO)-PYRIMIDINE manufacturers

Career Henan Chemical Co

Product: FAPy-adenine 5122-36-1
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 1ton
Release date: 2020-01-10

5122-36-1, 4,6-DIAMINO-5-(FORMYLAMINO)-PYRIMIDINERelated Search:

4-Amino-2,6-dimethoxypyrimidine 2,4,6-Triaminopyrimidine 4,6-DIAMINO-5-FORMAMIDOPYRIMIDINE (FORMYL-13C, DIAMINO-15N2) 4,6-DIAMINO-5-(FORMYLAMINO)-PYRIMIDINE 8-OXO-DA CEP 8-OXO-2'-DEOXYADENOSINE-5'-TRIPHOSPHATE LITHIUM SALT 8-HYDROXYADENINE 2'-deoxy-7,8-dihydro-8-oxoadenosine

4,6-diamino-5-n-formamidopyrimidine

4,6-Diaminobenzene-5-formamidopyrimide-formyl-13C, diamino-15N2

4,6-DIAMONO-5-(FORMYLAMINO)PYRIMIDNE

FAPy-adenine

DIAMINO-15N2)

FAPYADENINE(FORMYL-13C

DIAMINO-15N2, 98%)

4,6-Diamino-5-(Formylamino)-Pyrimidine HCl

N-(4,6-Diaminopyrimidin-5-yl)formamide

4,6-DIAMINO-5-(FORMYLAMINO)-PYRIMIDINE

Formamide, N-(4,6-diamino-5-pyrimidinyl)-

Adenosine Impurity 33

4,6 diamino-5-formamide pyrimidine HCl

5122-36-1

CC4H7N2N3O

C5H7N5OHCl

CC4H7N2N30

Biochemicals and Reagents

BioChemical

Nucleosides, Nucleotides, Oligonucleotides

Nucleoside Analogs

Biochemicals and Reagents

Nucleoside Analogs

Nucleosides, Nucleotides, Oligonucleotides