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Amino-PEG5-t-butyl acetate

Product Name
Amino-PEG5-t-butyl acetate
CAS No.
2231845-67-1
Chemical Name
Amino-PEG5-t-butyl acetate
Synonyms
NH2-PEG5-C1-Boc;H2N-PEG5-CH2COOtBu;NH2-PEG5-CH2COOtBu;Amino-PEG5-CH2COOtBu;Amino-PEG5-t-butyl acetate;tert-butyl 17-amino-3,6,9,12,15-pentaoxaheptadecanoate;3,6,9,12,15-Pentaoxaheptadecanoic acid,17-amino-, 1,1-dimethylethyl ester;H2N-PEG5-CH2COOtBu/3,6,9,12,15-Pentaoxaheptadecanoic acid, 17-amino-, 1,1-dimethylethyl ester
CBNumber
CB14858565
Molecular Formula
C16H33NO7
Formula Weight
351.44
MOL File
2231845-67-1.mol
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Acrotein
Product number
B-1410
Product name
H2N-PEG5-CH2COOtBu
Purity
97%
Packaging
1g
Price
$421.7
Updated
2021/12/16
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Amino-PEG5-t-butyl acetate Chemical Properties,Usage,Production

Biological Activity

NH2-PEG5-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Amino-PEG5-t-butyl acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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Amino-PEG5-t-butyl acetate Suppliers

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2231845-67-1, Amino-PEG5-t-butyl acetateRelated Search:


  • Amino-PEG5-t-butyl acetate
  • 3,6,9,12,15-Pentaoxaheptadecanoic acid,17-amino-, 1,1-dimethylethyl ester
  • H2N-PEG5-CH2COOtBu
  • NH2-PEG5-C1-Boc
  • NH2-PEG5-CH2COOtBu
  • tert-butyl 17-amino-3,6,9,12,15-pentaoxaheptadecanoate
  • H2N-PEG5-CH2COOtBu/3,6,9,12,15-Pentaoxaheptadecanoic acid, 17-amino-, 1,1-dimethylethyl ester
  • Amino-PEG5-CH2COOtBu
  • 2231845-67-1