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APF

Product Name
APF
CAS No.
359010-70-1
Chemical Name
APF
Synonyms
APF;AMINOPHENYL FLUORESCEIN;3-(p-Aminophenyl)fluorescein;3-(p-Aminophenyl)fluorescein , APF;2-[3-(4-aminophenoxy)-6-oxoxanthen-9-yl]benzoic acid;2-[6-(4'-AMINO)PHENOXY-3H-XANTHEN-3-ON-9-YL]BENZOIC ACID;2-[6-(4-AMINOPHENOXY)-3-OXO-3H-XANTHEN-9-YL]-BENZOIC ACID;3'-(4-aminophenoxy)-6'-hydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one;Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3'-(4-aminophenoxy)-6'-hydroxy-
CBNumber
CB1488937
Molecular Formula
C26H17NO5
Formula Weight
423.42
MOL File
Mol file
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APF Property

Boiling point:
677.7±55.0 °C(Predicted)
Density 
1.52±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF:20.0(Max Conc. mg/mL);47.23(Max Conc. mM)
DMSO:10.0(Max Conc. mg/mL);23.62(Max Conc. mM)
Ethanol:10.0(Max Conc. mg/mL);23.62(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:3):0.5(Max Conc. mg/mL);1.18(Max Conc. mM)
form 
Pale yellow liquid.
pka
9.61±0.20(Predicted)
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10157
Product name
APF
Purity
≥98%
Packaging
500μg
Price
$152
Updated
2024/03/01
Cayman Chemical
Product number
10157
Product name
APF
Purity
≥98%
Packaging
1mg
Price
$288
Updated
2024/03/01
Cayman Chemical
Product number
10157
Product name
APF
Purity
≥98%
Packaging
5mg
Price
$1204
Updated
2024/03/01
AK Scientific
Product number
1619AH
Product name
2-[6-(4-Aminophenoxy)-3-oxo-3H-xanthen-9-yl]-benzoicacid
Packaging
1mg
Price
$418
Updated
2021/12/16
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APF Chemical Properties,Usage,Production

Description

APF is an aromatic amino-fluorescein derivative and fluorescent probe for highly reactive radicals. It has low intrinsic fluorescence, however, upon oxidation by hydroxyl radical, hypochlorite ion, and certain peroxidase intermediates, it is converted to the highly fluorescent molecule fluorescein, facilitating the detection of highly reactive biological radicals. APF is not oxidized by nitric oxide (NO), hydrogen peroxide (H2O2), or other oxidants. Fluorescein displays excitation/emission maxima of 490/515 nm, respectively.

Uses

APF is a fluorescence probe that can selectively, and dose dependently detect certain species among ROS and that are highly resistant to autoxidation. APF can be used in enzymatic and cellular systems[1].

References

[1] Setsukinai K, et al. Development of novel fluorescence probes that can reliably detect reactive oxygen species and distinguish specific species. J Biol Chem. 2003;278(5):3170-3175. DOI:10.1074/jbc.M209264200

APF Preparation Products And Raw materials

Raw materials

Preparation Products

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APF Suppliers

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359010-70-1, APFRelated Search:

ROS Probe, HPF

  • 3'-(4-aminophenoxy)-6'-hydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one
  • APF
  • 2-[6-(4'-AMINO)PHENOXY-3H-XANTHEN-3-ON-9-YL]BENZOIC ACID
  • 2-[6-(4-AMINOPHENOXY)-3-OXO-3H-XANTHEN-9-YL]-BENZOIC ACID
  • AMINOPHENYL FLUORESCEIN
  • 2-[3-(4-aminophenoxy)-6-oxoxanthen-9-yl]benzoic acid
  • Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3'-(4-aminophenoxy)-6'-hydroxy-
  • 3-(p-Aminophenyl)fluorescein , APF
  • 3-(p-Aminophenyl)fluorescein
  • 359010-70-1