8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine dihydrochloride

Product Name: 8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine dihydrochloride
CAS No.: 2250025-93-3
Chemical Name: 8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine dihydrochloride
Synonyms: Clozapine N-oxide 2HCl;Clozapine N-oxide diHCl;Clozapine N-oxide dihydrochloride;Clozapine N-oxide dihydrochloride salt;8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine dihydrochloride
CBNumber: CB14902693
Molecular Formula: C18H21Cl3N4O-
Formula Weight: 415.74454
MOL File: 2250025-93-3.mol

More

Less

8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine dihydrochloride Property

storage temp.: Store at 4°C,stored under nitrogen
solubility: Soluble in DMSO
form: A crystalline solid
color: Orange
Water Solubility: Soluble in water (100 mM). Always store solutions at -20°C.

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H336May cause drowsiness or dizziness

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 25780
Product name: Clozapine N-oxide (hydrochloride)
Purity: ≥98%
Packaging: 5 mg
Price: $55
Updated: 2024/03/01

Cayman Chemical

Product number: 25780
Product name: Clozapine N-oxide (hydrochloride)
Purity: ≥98%
Packaging: 10 mg
Price: $99
Updated: 2024/03/01

Cayman Chemical

Product number: 25780
Product name: Clozapine N-oxide (hydrochloride)
Purity: ≥98%
Packaging: 25 mg
Price: $179
Updated: 2024/03/01

Cayman Chemical

Product number: 25780
Product name: Clozapine N-oxide (hydrochloride)
Purity: ≥98%
Packaging: 50 mg
Price: $330
Updated: 2024/03/01

Tocris

Product number: 6329
Product name: ClozapineN-oxidedihydrochloride
Purity: ≥99%(HPLC)
Packaging: 50
Price: $531
Updated: 2021/12/16

More

Less

8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine dihydrochloride Chemical Properties,Usage,Production

Biological Activity

Clozapine N-oxide dihydrochloride is a major metabolite of Clozapine and an agonist of human muscarinic designer receptors (DREADDs). It activates the DREADD receptors hM3Dq and hM4Di.

in vitro

Clozapine N-oxide (CNO) can bind to non-DREADD receptors at concentrations required for DREADD activation, and undergoes reverse-metabolism to its parent compound clozapine, an atypical antipsychotic that acts at a variety of pharmacological targets and produces numerous physiological and behavioral effects.

target

Human muscarinic designer receptors (DREADDs)

storage

-20°C

8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine dihydrochloride Suppliers

China 16 United Kingdom 1 United States 4 Global 21

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9805
Advantage: 58

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Jinan Jiuli Biotechnology Co. , Ltd.

Tel: 15865264761
Email: 486064515@qq.com
Country: China
ProdList: 4996
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29774
Advantage: 58

InvivoChem

Tel: 13549236410
Email: sales@invivochem.cn
Country: China
ProdList: 6753
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24644
Advantage: 58

Shanghai Tachizaki Biomedical Research Center

Tel: 18014399201
Email: sales@chemlab-tachizaki.com
Country: China
ProdList: 2619
Advantage: 58

Nantong QuanYi Biotechnology Co., Ltd

Tel: 0513-66337626 18051384581
Email: sales@chemhifuture.com
Country: China
ProdList: 5127
Advantage: 58

Shanghai Beiwanta Biotechnology Co., Ltd.

Tel: 021-67187366 19901745723
Email: info@bwtlab.com
Country: China
ProdList: 9367
Advantage: 58

Shandong Mopai Biotechnology Co., Ltd

Tel: 13070690626
Email: admin@mopaikeji.com
Country: China
ProdList: 3786
Advantage: 58

Shanghai Aladdin Biochemical Technology Co.,Ltd.

Tel: 400-6206333 18021050169
Email: market@aladdin-e.com
Country: China
ProdList: 48461
Advantage: 58

Shanghai Qianhao Biotechnology Co., LTD

Tel: 13524877553
Email: 13524877553@163.com
Country: China
ProdList: 52
Advantage: 58

R&D Systems, Inc

Tel: 18003437475
Email: rdname@qq.com
Country: CHINA
ProdList: 35705
Advantage: 58

Tel
Email: sangon@qq.com
Country: CHINA
ProdList: 47239
Advantage: 58

Biorbyt Ltd.

Tel: --
Fax: --
Email: info@biorbyt.com
Country: CHINA
ProdList: 6579
Advantage: 58

2250025-93-3, 8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine dihydrochlorideRelated Search:

8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine dihydrochloride

Clozapine N-oxide dihydrochloride

Clozapine N-oxide dihydrochloride salt

Clozapine N-oxide diHCl

Clozapine N-oxide 2HCl

2250025-93-3