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ISOMITRAPHYLLINE

Product Name
ISOMITRAPHYLLINE
CAS No.
4963-01-3
Chemical Name
ISOMITRAPHYLLINE
Synonyms
ISOMITRAPHYLLINE;7-Isomitraphylline;Isomitraphylline-RM;AJMALICIN OXINDOLE A;ISOMITRAPHYLLINE(SH);Ajmalicine oxindole A;(7S)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester;Spiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid, 1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2-oxo-, methyl ester, (1'S,3S,4'aS,5'aS,10'aR)-
CBNumber
CB1490378
Molecular Formula
C21H24N2O4
Formula Weight
368.43
MOL File
4963-01-3.mol
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ISOMITRAPHYLLINE Property

Boiling point:
555.2±50.0 °C(Predicted)
Density 
1.33±0.1 g/cm3(Predicted)
storage temp. 
-20°C
pka
13.56±0.60(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL89718
Product name
Isomitraphylline
Purity
phyproof? Reference Substance
Packaging
10mg
Price
$608
Updated
2024/03/01
TRC
Product number
I821363
Product name
Isomitraphylline
Packaging
10mg
Price
$210
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0003036
Product name
ISOMITRAPHYLLINE
Purity
95.00%
Packaging
5MG
Price
$504
Updated
2021/12/16
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ISOMITRAPHYLLINE Chemical Properties,Usage,Production

Description

This Mitragyna alkaloid has been isolated from the leaves of M. speciosa Korth by Beckett and his colleagues. It is an amorphous solid which cannot be obtained crystalline. The base may be characterized as the picrate which forms pale yellow needles from MeOH, m.p. 223°C (dec.). A methylgroup, a methoxycarbonyl group and one imino group are present. The second nitrogen atom is tertiary.

Uses

Isomitraphylline is an oxoindole alkaloid derivied from amazonian plants and maintain medicinal benefits. Used in the treatment of ulcers, arthritis, etc.

Biological Activity

Isomitraphylline, an oxindole alkaloid, has potent anti-cancer activity.

References

Beckett et al., J. Pharm. Pharmacol., 17,753 (1965) Beckett et ai., Planta Med., 14, 266 (1966) Structure: Finch, Taylor., J. Amer. Chem. Soc., 84,3871 (1962) Prepara tion: Seaton et al., Can. J. Chem., 38, 1035 (1960)

ISOMITRAPHYLLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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ISOMITRAPHYLLINE Suppliers

BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5653
Advantage
65
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7887
Advantage
56
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27313
Advantage
60
Chengdu Push Bio-Technology Co., Ltd.
Tel
028-85370565-229 18080489829
Email
3004654993@qq.com
Country
China
ProdList
8899
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60
Nanjing Digger Medical Technology Co. Ltd.
Tel
025-025-51191215 18013836722
Fax
025-51191215
Email
2399235533@qq.com
Country
China
ProdList
4933
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57412
Advantage
58
Labnetwork lnc.
Tel
+86-27-50766799 +8618062016861
Email
contact@labnetwork.com
Country
China
ProdList
19987
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58
Aktin Chemicals, Inc.
Tel
028-85159085
Fax
86-28-85159085 Ex:604
Email
info@aktinchem.com
Country
CHINA
ProdList
1025
Advantage
58
Shanghai Bohu Biotechnology Co., LTD
Tel
021-57763112 13585886131
Email
3004987436@qq.com
Country
China
ProdList
9693
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58

4963-01-3, ISOMITRAPHYLLINERelated Search:


  • AJMALICIN OXINDOLE A
  • (7S)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester
  • 7-Isomitraphylline
  • Ajmalicine oxindole A
  • ISOMITRAPHYLLINE(SH)
  • ISOMITRAPHYLLINE
  • Spiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid, 1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2-oxo-, methyl ester, (1'S,3S,4'aS,5'aS,10'aR)-
  • Isomitraphylline-RM
  • 4963-01-3