Uses In vitro Storage
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Doxorubicin-SMCC

Uses In vitro Storage
Product Name
Doxorubicin-SMCC
CAS No.
400647-59-8
Chemical Name
Doxorubicin-SMCC
Synonyms
Doxorubicin-SMCC;N-(4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexane)-Doxorubicin;5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[[[4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]cyclohexyl]carbonyl]amino]-α-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)-
CBNumber
CB14919822
Molecular Formula
C39H42N2O14
Formula Weight
762.76
MOL File
400647-59-8.mol
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Doxorubicin-SMCC Property

Melting point:
162-172 °C
Boiling point:
1022.5±65.0 °C(Predicted)
Density 
1.56±0.1 g/cm3(Predicted)
solubility 
Soluble in DMSO, DMF
form 
Solid
pka
7.35±0.60(Predicted)
color 
Orange to red
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-24433
Product name
N-(4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexane)-Doxorubicin
Purity
98%
Packaging
50mg
Price
$780
Updated
2021/12/16
BroadPharm
Product number
BP-24433
Product name
N-(4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexane)-Doxorubicin
Purity
98%
Packaging
100mg
Price
$1400
Updated
2021/12/16
BroadPharm
Product number
BP-24433
Product name
N-(4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexane)-Doxorubicin
Purity
98%
Packaging
250mg
Price
$2500
Updated
2021/12/16
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Doxorubicin-SMCC Chemical Properties,Usage,Production

Uses

Doxorubicin-SMCC is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

In vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Description

N-(4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexane)-Doxorubicin is a maleimide attached Doxorubicin. It can conjugate with thiol containing molecules.

Doxorubicin-SMCC Preparation Products And Raw materials

Raw materials

Preparation Products

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Doxorubicin-SMCC Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52924
Advantage
58
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
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58

400647-59-8, Doxorubicin-SMCCRelated Search:


  • Doxorubicin-SMCC
  • N-(4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexane)-Doxorubicin
  • 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[[[4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]cyclohexyl]carbonyl]amino]-α-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)-
  • 400647-59-8
  • C39H42N2O14
  • ADC LINKER