ChemicalBook > CAS DataBase List > N-Caffeoyltryptophan
N-Caffeoyltryptophan
- Product Name
- N-Caffeoyltryptophan
- CAS No.
- 109163-69-1
- Chemical Name
- N-Caffeoyltryptophan
- Synonyms
- N-Caffeoyltryptophan;trans-Caffeoyl-L-tryptophan;trans-Caffeoyl-L-tryptophan sodium salt;N Caffeoyltryptophan,NCaffeoyltryptophan;L-Tryptophan, N-[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]-
- CBNumber
- CB14925397
- Molecular Formula
- C20H18N2O5
- Formula Weight
- 366.37
- MOL File
- 109163-69-1.mol
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N-Caffeoyltryptophan Property
- Boiling point:
- 771.3±60.0 °C(Predicted)
- Density
- 1.460±0.06 g/cm3(Predicted)
- pka
- 3?+-.0.10(Predicted)
- form
- Solid
- color
- White to off-white
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N-Caffeoyltryptophan Chemical Properties,Usage,Production
Uses
Caffeoyltryptophan is a competitive PTP1B inhibitor, with an IC50 of 16.99 μM. Caffeoyltryptophan can also inhibit α-glucosidase, linoleic acid peroxidation and haemolysis. Caffeoyltryptophan can be used for the research of type 2 diabetes[1].
Definition
ChEBI: N-Caffeoyltryptophan is a N-acyl-amino acid.
References
[1] Ha MT, et, al. PTP1B and α-glucosidase inhibitory activities of the chemical constituents from Hedera rhombea fruits: Kinetic analysis and molecular docking simulation. Phytochemistry. 2022 May:197:113100. DOI:10.1016/j.phytochem.2022.113100
[2] Ohnishi M, et, al. Inhibition in vitro linoleic acid peroxidation and haemolysis by caffeoyltryptophan. Phytochemistry. 1998 Apr;47(7):1215-8. DOI:10.1016/s0031-9422(97)00754-1
N-Caffeoyltryptophan Preparation Products And Raw materials
Raw materials
Preparation Products
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