METHYL 5-FLUORO-2-HYDROXYBENZOATE

Synthesis

Product Name: METHYL 5-FLUORO-2-HYDROXYBENZOATE
CAS No.: 391-92-4
Chemical Name: METHYL 5-FLUORO-2-HYDROXYBENZOATE
Synonyms: Methyl 5-Fluorosalicylate;Methyl 2-hydroxy-5-fluorobenzoate;4-Fluoro-2-(methoxycarbonyl)phenol;Methyl5-fluoro-2-hydroxybenzoate98%;Methyl 5-fluoro-2-hydroxybenzoate 98%;Methyl 5-fluoro-2-hydroxybenzoate,97%;Methyl 5-fluoro-2-hydroxybenzoate, 97% 5GR;5-FLUORO-2-HYDROXY-BENZOIC ACID METHYL ESTER;Benzoic acid, 5-fluoro-2-hydroxy-, methyl ester;JR-13536, Methyl 5-fluoro-2-hydroxybenzoate, 96%
CBNumber: CB1501195
Molecular Formula: C8H7FO3
Formula Weight: 170.14
MOL File: 391-92-4.mol

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METHYL 5-FLUORO-2-HYDROXYBENZOATE Property

Melting point:: 30-34
Boiling point:: 50/0.15mm
Density: 1.309±0.06 g/cm3(Predicted)
Flash point:: 105
storage temp.: Sealed in dry,Room Temperature
pka: 9.77±0.18(Predicted)
form: Low Melting Solid
color: Pale yellow
CAS DataBase Reference: 391-92-4

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
Hazard Note: Irritant
HS Code: 29182900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: M320073
Product name: Methyl5-Fluoro-2-hydroxybenzoate
Packaging: 500mg
Price: $155
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0014226
Product name: METHYL 5-FLUORO-2-HYDROXYBENZOATE
Purity: 95.00%
Packaging: 1G
Price: $684.92
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0014226
Product name: METHYL 5-FLUORO-2-HYDROXYBENZOATE
Purity: 95.00%
Packaging: 5G
Price: $1130.75
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0014226
Product name: METHYL 5-FLUORO-2-HYDROXYBENZOATE
Purity: 95.00%
Packaging: 25G
Price: $2130.98
Updated: 2021/12/16

Apolloscientific

Product number: PC10377
Product name: Methyl5-fluoro-2-hydroxybenzoate
Purity: 98%
Packaging: 1g
Price: $50
Updated: 2021/12/16

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METHYL 5-FLUORO-2-HYDROXYBENZOATE Chemical Properties,Usage,Production

Synthesis

Methyl 5-fluoro-2-hydroxybenzoate is synthesized by esterification of 5-fluorosalicylic acid with methanol.

Chemical Properties

Pale yellow low melting solid

Uses

Methyl 5-fluoro-2-hydroxybenzoate can be used as pharmaceutical intermediates and organic synthesis intermediates, for laboratory research.

References

[1] Patent: EP2813495, 2014, A1. Location in patent: Paragraph 0016
[2] Patent: US2015/18542, 2015, A1. Location in patent: Paragraph 0063; 0064; 0065
[3] Journal of Medicinal Chemistry, 2014, vol. 57, # 13, p. 5579 - 5601
[4] Patent: WO2016/96686, 2016, A1. Location in patent: Page/Page column 83
[5] Patent: WO2017/211759, 2017, A1. Location in patent: Page/Page column 46

METHYL 5-FLUORO-2-HYDROXYBENZOATE Preparation Products And Raw materials

Raw materials

Preparation Products

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METHYL 5-FLUORO-2-HYDROXYBENZOATE Suppliers

China 114 India 1 Switzerland 1 United Kingdom 1 United States 11 Global 128

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391-92-4, METHYL 5-FLUORO-2-HYDROXYBENZOATERelated Search:

2-NITRO-5-FLUOROBENZOIC ACID, METHYL ESTER Hyaluronic acid 5-Fluoro-2-hydroxy-3-nitro-benzoic acid methyl ester methyl 5-fluoro-6-methylnicotinate Methyl 5-fluoro-2-methyl-3-nitrobenzoate Methyl 5-fluoro-2-iodobenzoate Methyl 5-fluoro-2-(MethylaMino)benzoate 5-FLUORO-2-HYDROXYBENZOIC ACID ETHYL ESTER METHYL 5-FLUORO-2-HYDROXYBENZOATE 2,3-DIFLUORO-6-HYDROXYBENZOIC ACID ETHYL ESTER methyl 4,5-difluoro-2-methoxybenzoate 3,5-DIFLUORO-2-HYDROXY-BENZOIC ACID METHYL ESTER RARECHEM AL BF 1426 RARECHEM AL BI 1275 RARECHEM AL BI 1422 RARECHEM AL BI 1426 RARECHEM AL BF 1311 5-FLUORO-2-METHOXYBENZOIC ACID METHYL ESTER

JR-13536, Methyl 5-fluoro-2-hydroxybenzoate, 96%

5-FLUORO-2-HYDROXY-BENZOIC ACID METHYL ESTER

Methyl 5-fluoro-2-hydroxybenzoate,97%

4-Fluoro-2-(methoxycarbonyl)phenol

Methyl 5-fluoro-2-hydroxybenzoate, 97% 5GR

4-Fluoro-2-(methoxycarbonyl)phenol, Methyl 5-fluorosalicylate

Methyl 5-fluoro-2-hydroxybenzoate 98%

Methyl5-fluoro-2-hydroxybenzoate98%

Methyl 5-Fluorosalicylate

Benzoic acid, 5-fluoro-2-hydroxy-, methyl ester

Methyl 2-hydroxy-5-fluorobenzoate

391-92-4

FC6H3OHCO2CH3

Benzoic acid

C8 to C9

Carbonyl Compounds

Esters