ChemicalBook > CAS DataBase List > METHYL ALPHA-BROMOACRYLATE 95

METHYL ALPHA-BROMOACRYLATE 95

Product Name: METHYL ALPHA-BROMOACRYLATE 95
CAS No.: 4519-46-4
Chemical Name: METHYL ALPHA-BROMOACRYLATE 95
Synonyms: methyl α-bromoacrylate;Methyl α-bromoacrylate;Methyl 2-bromoprop-2-enoate;METHYL ALPHA-BROMOACRYLATE 95;Methyl alpha-bromoacrylate 95%;2-Bromopropenoic acid methyl ester;Methyl α-bromoacrylate, CAS 4519-46-4;2-Propenoic acid, 2-broMo-, Methyl ester
CBNumber: CB1505148
Molecular Formula: C4H5BrO2
Formula Weight: 164.99
MOL File: 4519-46-4.mol

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METHYL ALPHA-BROMOACRYLATE 95 Property

Boiling point:: 70-75 °C48 mm Hg(lit.)
Density: 1.556 g/mL at 25 °C(lit.)
Flash point:: 134 °F
storage temp.: -20°C
Appearance: Colorless to light yellow Liquid
InChI: InChI=1S/C4H5BrO2/c1-3(5)4(6)7-2/h1H2,2H3
InChIKey: HVJXPDPGPORYKY-UHFFFAOYSA-N
SMILES: C(OC)(=O)C(Br)=C
CAS DataBase Reference: 4519-46-4

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
RIDADR: UN 1993 3/PG 3
WGK Germany: 3
HazardClass: 3
PackingGroup: Ⅲ
HS Code: 2916199590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 588466
Product name: Methyl α-bromoacrylate
Purity: 95%
Packaging: 1g
Price: $237.5
Updated: 2025/07/31

TRC

Product number: M219780
Product name: Methyl2-Bromoacrylate
Packaging: 100mg
Price: $60
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0098802
Product name: METHYL ALPHA-BROMOACRYLATE
Purity: 98.00%
Packaging: 1G
Price: $937.46
Updated: 2021/12/16

Ambeed

Product number: A817668
Product name: Methyl2-bromoacrylate
Purity: 98%(stabilizedwithMEHQ)
Packaging: 25g
Price: $950
Updated: 2021/12/16

Ambeed

Product number: A817668
Product name: Methyl2-bromoacrylate
Purity: 98%(stabilizedwithMEHQ)
Packaging: 250mg
Price: $37
Updated: 2021/12/16

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METHYL ALPHA-BROMOACRYLATE 95 Chemical Properties,Usage,Production

Uses

Methyl α-bromoacrylate can undergo radical copolymerization with vinyl triacetoxysilane (VTAS) in the presence of azobisisobutyronitrile as the initiator. Dibromocyclopropanation of methyl α-bromoacrylate can yield methyl 1,1,2-tribromocyclopropanecarboxylate. It may be reduced with zinc dust and deuterium oxide to synthesize. Methyl acrylate-α-d with a high isotopic purity. These may undergo conjugate addition with methoxide, thiolates, oxime anions, hydrazones and EtZnCl to afford ester enolates.

Synthesis

292638-85-8

4519-46-4

Example-1 Preparation of α-bromo methyl acrylate: methyl acrylate (100 g) was mixed with dichloromethane (300 mL) and cooled to 0-5°C. Bromine (60 mL) was slowly added dropwise at 0-5°C and the dropwise process lasted for 1 hour. After completion of the reaction, the reaction mixture was stirred at 25-30 °C for 4-5 hours. Subsequently, 10% NaHCO3 solution (100 mL) was added, stirred for 30 minutes and left to stratify. Sodium carbonate (250 g) and triethylamine (160 mL) were added to the dichloromethane layer and stirred at 25-30 °C for 1 hour. The mixture was kept at the same temperature for 2 hours and then filtered. To the filtrate, 20% HCl solution (100 mL) was added, stirred for 30 minutes and left to stratify. The organic layer was washed with 20% HCl solution (100 mL). Finally, the solvent was removed by distillation under reduced pressure at less than 30 °C to give α-bromoacrylic acid methyl ester. Yield: 140 g.

References

[1] Journal of Organic Chemistry, 2004, vol. 69, # 24, p. 8561 - 8563
[2] Patent: WO2012/25936, 2012, A2. Location in patent: Page/Page column 8-9
[3] Patent: US2013/184469, 2013, A1. Location in patent: Paragraph 0027
[4] Patent: US2016/287726, 2016, A1. Location in patent: Paragraph 0079; 0080

METHYL ALPHA-BROMOACRYLATE 95 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from METHYL ALPHA-BROMOACRYLATE 95 manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: Methyl 2-bromoacrylate 4519-46-4
Price: US $22.00-88.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20kg
Release date: 2025-06-25

Shaanxi Dideu Medichem Co. Ltd

Product: METHYL ALPHA-BROMOACRYLATE 95 4519-46-4
Price: US $25.00-11.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200000KG
Release date: 2024-08-12

Career Henan Chemical Co

Product: Methyl 2-bromoacrylate 4519-46-4
Price: US $1.00/g
Min. Order: 1g
Purity: 95--99%
Supply Ability: 1ton
Release date: 2020-01-09

4519-46-4, METHYL ALPHA-BROMOACRYLATE 95Related Search:

Methacrylic acid

methyl α-bromoacrylate

2-Bromopropenoic acid methyl ester

Methyl 2-bromoprop-2-enoate

2-Propenoic acid, 2-broMo-, Methyl ester

Methyl alpha-bromoacrylate 95%

METHYL ALPHA-BROMOACRYLATE 95

Methyl α-bromoacrylate, CAS 4519-46-4

Methyl α-bromoacrylate

4519-46-4

AcrylateCarbonyl Compounds

Acrylic Monomers

C2 to C5

Esters

Monomers