1-BROMO-2,5-BIS(3-CARBOXY-4-HYDROXYSTYRYL)BENZENE
- Product Name
- 1-BROMO-2,5-BIS(3-CARBOXY-4-HYDROXYSTYRYL)BENZENE
- CAS No.
- 291766-06-8
- Chemical Name
- 1-BROMO-2,5-BIS(3-CARBOXY-4-HYDROXYSTYRYL)BENZENE
- Synonyms
- BSB;SBS probe;1-BROMO-2,5-BIS(3-CARBOXY-4-HYDROXYSTYRYL)BENZENE;(trans, trans)-1-BroMo-2,5-bis-(3-carboxy-4-hydroxy)styrylbenzene;Benzoic acid, 3,3'-[(2-bromo-1,4-phenylene)di-(1E)-2,1-ethenediyl]bis[6-hydroxy-;5,5'-((1E,1'E)-(2-Bromo-1,4-phenylene)bis(ethene-2,1-diyl))bis(2-hydroxybenzoic acid)
- CBNumber
- CB1511325
- Molecular Formula
- C24H17BrO6
- Formula Weight
- 481.29218
- MOL File
- 291766-06-8.mol
1-BROMO-2,5-BIS(3-CARBOXY-4-HYDROXYSTYRYL)BENZENE Property
- Boiling point:
- 705.5±60.0 °C(Predicted)
- Density
- 1.637±0.06 g/cm3(Predicted)
- storage temp.
- 4°C, protect from light
- solubility
- DMSO : 100 mg/mL (207.77 mM; ultrasonic and warming and heat to 60°C)
- form
- Solid
- pka
- 3.10±0.10(Predicted)
- color
- Light yellow to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
1-BROMO-2,5-BIS(3-CARBOXY-4-HYDROXYSTYRYL)BENZENE Chemical Properties,Usage,Production
Uses
BSB is a Congo red-derived fluorescent probe. BSB binds not only to extracellular amyloid β protein, but also many intracellular lesions composed of abnormal tau and synuclein proteins. BSB acts as a prototype imaging agent for Alzheimer's disease[1].
References
[1] M L Schmidt, et al. The fluorescent Congo red derivative, (trans, trans)-1-bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene (BSB), labels diverse beta-pleated sheet structures in postmortem human neurodegenerative disease brains. Am J Pathol. 2001 Sep;159(3):937-43. DOI:10.1016/s0002-9440(10)61769-5
1-BROMO-2,5-BIS(3-CARBOXY-4-HYDROXYSTYRYL)BENZENE Preparation Products And Raw materials
Raw materials
Preparation Products
1-BROMO-2,5-BIS(3-CARBOXY-4-HYDROXYSTYRYL)BENZENE Suppliers
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 15402
- Advantage
- 60
- Tel
- 027-86697669 13986148687
- Fax
- 86-027-86697669
- sales@tcaschem.com
- Country
- China
- ProdList
- 3997
- Advantage
- 55
- Tel
- 021-QQ：65489617 15618227136
- Fax
- 21-5161 9052
- Sales@ATKchemical.com
- Country
- China
- ProdList
- 9025
- Advantage
- 58
- Tel
- 15971444841
- Fax
- 18327183813
- amber@biochempartner.com
- Country
- China
- ProdList
- 3061
- Advantage
- 58
- Tel
- 18051384581
- sales@chemhifuture.com
- Country
- China
- ProdList
- 2957
- Advantage
- 58
- Tel
- 400-1647117 13681763483
- product02@bidepharm.com
- Country
- China
- ProdList
- 59936
- Advantage
- 58
- Tel
- 4008200310
- marketing@tsbiochem.com
- Country
- China
- ProdList
- 24962
- Advantage
- 58
- Tel
- 18014399201
- sales@chemlab-tachizaki.com
- Country
- China
- ProdList
- 2761
- Advantage
- 58
- Tel
- 025-58906079 17352406906
- sales@bicbiotech.com
- Country
- China
- ProdList
- 5834
- Advantage
- 58
- Tel
- 18168818882 15961169601;
- 877458914@qq.com
- Country
- China
- ProdList
- 8743
- Advantage
- 58