AZ7550 hydrochloride

Product Name: AZ7550 hydrochloride
CAS No.: 2309762-40-9
Chemical Name: AZ7550 hydrochloride
Synonyms: RMA-291;AZ7550 hydrochloride;EGFR,ErbB-1,Epidermal growth factor receptor,HER1,Drug Metabolite,AZ7550 hydrochloride,inhibit,AZ7550,AZ-7550,AZ 7550,Inhibitor,IGF-1R,AZ-7550 hydrochloride
CBNumber: CB15419680
Molecular Formula: C??H??ClN?O?
Formula Weight: 522.05
MOL File: 2309762-40-9.mol

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AZ7550 hydrochloride Property

storage temp.: Store at -20°C
solubility: DMSO : 1.88 mg/mL (3.60 mM)
form: Solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0034377
Product name: AZ7550hydrochloride
Purity: 98.66%
Packaging: 5mg
Price: $280
Updated: 2021/12/16

ChemScene

Product number: CS-0034377
Product name: AZ7550hydrochloride
Purity: 98.66%
Packaging: 10mg
Price: $440
Updated: 2021/12/16

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AZ7550 hydrochloride Chemical Properties,Usage,Production

Uses

AZ7550 hydrochloride is an active metabolite of AZD9291 and inhibits the activity of IGF1R with an IC50 of 1.6 μM.

References

[1] Finlay MR, et al. Discovery of a potent and selective EGFR inhibitor (AZD9291) of both sensitizing and T790M resistance mutations that spares the wild type form of the receptor. J Med Chem. 2014 Oct 23;57(20):8249-67. DOI:10.1021/jm500973a

AZ7550 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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AZ7550 hydrochloride Suppliers

China 23 United States 5 Global 28

Daicel Chiral Technologies (China)CO.,LTD

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2309762-40-9, AZ7550 hydrochlorideRelated Search:

AZ7550 hydrochloride

EGFR,ErbB-1,Epidermal growth factor receptor,HER1,Drug Metabolite,AZ7550 hydrochloride,inhibit,AZ7550,AZ-7550,AZ 7550,Inhibitor,IGF-1R,AZ-7550 hydrochloride

RMA-291

2309762-40-9