Tauroursodeoxycholate dihydrate

Product Name: Tauroursodeoxycholate dihydrate
CAS No.: 117609-50-4
Chemical Name: Tauroursodeoxycholate dihydrate
Synonyms: UR 906 dihydrate;Taurolite dihydrate);Tauroursodeoxycholate dihydrate;Tauroursodeoxycholic Acid Dihydrate in Methanol;Tauroursodeoxycholate dihydrate (TUDCA dihydrate;TAUROURSODEOXYCHOLATE DIHYDRATE (TUDCA DIHYDRATE; UR 906 DIHYDRATE; TAUROLITE DIHYDRATE);2-((R)-4-((3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethane-1-sulfonic acid dihydrate
CBNumber: CB15419862
Molecular Formula: C26H47NO7S
Formula Weight: 517.72
MOL File: 117609-50-4.mol

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Tauroursodeoxycholate dihydrate Property

storage temp.: Store at -20°C
solubility: DMSO : 83.33 mg/mL (155.54 mM) ,Water:12.5mg/mL(25.02 mM)
form: Solid
color: White to off-white
InChIKey: XOSBJJOXVSXOFR-UWHYVWSJNA-N
SMILES: C[C@]12CC[C@]3([H])[C@]4(CC[C@@H](O)C[C@@]4([H])C[C@H](O)[C@@]3([H])[C@]1([H])CC[C@]2([H])[C@H](C)CCC(=O)NCCS(O)(=O)=O)C.O |&1:1,4,6,9,12,15,17,19,23,25,r|

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0094057
Product name: Tauroursodeoxycholatedihydrate
Purity: >98.0%
Packaging: 50mg
Price: $60
Updated: 2021/12/16

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Tauroursodeoxycholate dihydrate Chemical Properties,Usage,Production

Uses

Tauroursodeoxycholate (Tauroursodeoxycholic acid; TDUCA) dihydrate is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK[1][2].

IC 50

Human Endogenous Metabolite

References

[1] Kim SY, et al. Tauroursodeoxycholate (TUDCA) inhibits neointimal hyperplasia by suppression of ERK viaPKCα-mediated MKP-1 induction. Cardiovasc Res. 2011 Nov 1;92(2):307-16. DOI:10.1093/cvr/cvr219
[2] Qin Y, et al. Tauroursodeoxycholic Acid Attenuates Angiotensin II Induced Abdominal Aortic Aneurysm Formation in Apolipoprotein E-deficient Mice by Inhibiting Endoplasmic Reticulum Stress. Eur J Vasc Endovasc Surg. 2017 Mar;53(3):337-345. DOI:10.1016/j.ejvs.2016.10.026

Tauroursodeoxycholate dihydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Tauroursodeoxycholate dihydrate Suppliers

China 32 United States 4 Global 36

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117609-50-4, Tauroursodeoxycholate dihydrateRelated Search:

Tauroursodeoxycholate dihydrate

Taurolite dihydrate)

Tauroursodeoxycholate dihydrate (TUDCA dihydrate

TAUROURSODEOXYCHOLATE DIHYDRATE (TUDCA DIHYDRATE; UR 906 DIHYDRATE; TAUROLITE DIHYDRATE)

UR 906 dihydrate

Tauroursodeoxycholic Acid Dihydrate in Methanol

2-((R)-4-((3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethane-1-sulfonic acid dihydrate

117609-50-4