GLP-26
- Product Name
- GLP-26
- CAS No.
- 2133017-36-2
- Chemical Name
- GLP-26
- Synonyms
- GLP-26;GLP-26;GLP 26;GLP26;GLP-26, 10 mM in DMSO;inhibit,GLP26,GLP 26,Inhibitor,GLP-26,Hepatitis B virus,HBV;1H-Pyrrole-3-acetamide, 5-[[(3,4-difluorophenyl)amino]carbonyl]-1,2,4-trimethyl-α-oxo-N-2-propyn-1-yl-;N-(3,4-difluorophenyl)-1,3,5-trimethyl-4-(2-oxo-2-(prop-2-yn-1-ylamino)acetyl)-1H-pyrrole-2-carboxamide
- CBNumber
- CB15466174
- Molecular Formula
- C19H17F2N3O3
- Formula Weight
- 373.36
- MOL File
- 2133017-36-2.mol
GLP-26 Property
- Density
- 1.26±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 125 mg/mL (334.81 mM)
- form
- Solid
- pka
- 10.99±0.46(Predicted)
- color
- Light yellow to brown
N-Bromosuccinimide Price
- Product number
- CS-0087130
- Product name
- GLP-26
- Purity
- 98.13%
- Packaging
- 5mg
- Price
- $285
- Updated
- 2021/12/16
- Product number
- CS-0087130
- Product name
- GLP-26
- Purity
- 98.13%
- Packaging
- 10mg
- Price
- $385
- Updated
- 2021/12/16
- Product number
- CS-0087130
- Product name
- GLP-26
- Purity
- 98.13%
- Packaging
- 25mg
- Price
- $595
- Updated
- 2021/12/16
- Product number
- CS-0087130
- Product name
- GLP-26
- Purity
- 98.13%
- Packaging
- 50mg
- Price
- $980
- Updated
- 2021/12/16
- Product number
- CS-0087130
- Product name
- GLP-26
- Purity
- 98.13%
- Packaging
- 100mg
- Price
- $1580
- Updated
- 2021/12/16
GLP-26 Chemical Properties,Usage,Production
Description
GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system (IC50=3 nM), and reduces cccDNA by >90% at 1 μM.GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools[1].
GLP-26 (0.7-1.7 μM; 3 days) reduces secreted HBeAg in HepNTCP-DL cells transfected with HBVwild type, with EC50 values of 0.7 μM[2]. Cell Viability Assay[2] Cell Line: HepNTCP-DL cells
References
[1]. Nijampatnam B, et al. Recent advances in the development of HBV capsid assembly modulators. Curr Opin Chem Biol. 2019 Jun;50:73-79.
GLP-26 Preparation Products And Raw materials
Raw materials
Preparation Products
GLP-26 Suppliers
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- +1-781-999-5354 +1-00000000000
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- Country
- United States
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