ChemicalBook > CAS DataBase List > STAT3-IN-1
STAT3-IN-1
- Product Name
- STAT3-IN-1
- CAS No.
- 2059952-75-7
- Chemical Name
- STAT3-IN-1
- Synonyms
- STAT3-IN-1;STAT3-IN-1, 10 mM in DMSO;Inhibitor,STAT-3-IN-1,Apoptosis,inhibit,STAT3IN1,STAT,STAT3 IN 1;(E)-N-(4-((E)-3,5-Dimethoxystyryl)phenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide;2-Propenamide, N-[4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]phenyl]-3-(3,4,5-trimethoxyphenyl)-, (2E)-
- CBNumber
- CB15821188
- Molecular Formula
- C28H29NO6
- Formula Weight
- 475.53
- MOL File
- 2059952-75-7.mol
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STAT3-IN-1 Property
- Boiling point:
- 689.3±55.0 °C(Predicted)
- Density
- 1.205±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO: 125 mg/mL (262.86 mM)
- pka
- 12.63±0.70(Predicted)
- form
- Solid
- color
- Light yellow to orange
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0020241
- Product name
- STAT3-IN-1
- Purity
- 96.54%
- Packaging
- 5mg
- Price
- $150
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0020241
- Product name
- STAT3-IN-1
- Purity
- 96.54%
- Packaging
- 10mg
- Price
- $240
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0020241
- Product name
- STAT3-IN-1
- Purity
- 96.54%
- Packaging
- 50mg
- Price
- $680
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0020241
- Product name
- STAT3-IN-1
- Purity
- 96.54%
- Packaging
- 100mg
- Price
- $980
- Updated
- 2021/12/16
DC Chemicals
- Product number
- 020426
- Product name
- STAT3-IN-1
- Packaging
- 008
- Price
- $1900
- Updated
- 2021/12/16
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STAT3-IN-1 Chemical Properties,Usage,Production
Uses
STAT3-IN-1 is a STAT3 inhibitor. Antitumor activity.
in vivo
STAT3-IN-1 (compound 7d: 10, 20 mg/kg, two weeks) arrests tumor growth with low toxicity in mouse-xenograft model[1].
| Animal Model: | Mouse-xenograft model bearing inoculation of mice breast cancer 4T1 cells[1]. |
| Dosage: | 10, 20 mg/kg. |
| Administration: | Oral administration once every other day for two weeks. |
| Result: | Arrested tumor growth with no obvious body weight loss. |
IC 50
Stat-3: 1.82 μM (IC50, in HT29 cells); Stat-3: 2.14 μM (IC50, in MDA-MB 231 cells)
STAT3-IN-1 Preparation Products And Raw materials
Raw materials
Preparation Products
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STAT3-IN-1 Suppliers
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