PROTAC BRD4 ligand-1

Product Name: PROTAC BRD4 ligand-1
CAS No.: 2313230-51-0
Chemical Name: PROTAC BRD4 ligand-1
Synonyms: PROTAC BRD4 ligand-1;PROTAC BRD4 ligand 1,PROTAC BRD4 ligand1,PROTAC BRD-4 ligand-1;7-(3,5-difluoropyridin-2-yl)-2-methyl-10-((methylsulfonyl)methyl)-3-oxo-3,4,6,7-tetrahydro-2H-2,4,7-triazadibenzo[cd,f]azulene-9-carboxylic acid;2H-2,4,7-Triazadibenz[cd,f]azulene-9-carboxylic acid, 7-(3,5-difluoro-2-pyridinyl)-3,4,6,7-tetrahydro-2-methyl-10-[(methylsulfonyl)methyl]-3-oxo-;7-(3,5-Difluoro-2-pyridyl)-2-methyl-10-[(methylsulfonyl)methyl]-3-oxo-3,4,6,7-tetrahydro-2H-pyrido[3',4':6,7]azepino[3,4,5-cd]isoindole-9-carboxylic Acid;8-(3,5-difluoropyridin-2-yl)-15-methyl-4-(methylsulfonylmethyl)-14-oxo-8,12,15-triazatetracyclo[8.6.1.02,7.013,17]heptadeca-1(16),2(7),3,5,10,13(17)-hexaene-5-carboxylic acid;8-(3,5-difluoropyridin-2-yl)-4-(methanesulfonylmethyl)-15-methyl-14-oxo-8,12,15-triazatetracyclo[8.6.1.02,?.013,1?]heptadeca-1(16),2(7),3,5,10,13(17)-hexaene-5-carboxylic acid
CBNumber: CB15821289
Molecular Formula: C23H18F2N4O5S
Formula Weight: 500.47
MOL File: 2313230-51-0.mol

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PROTAC BRD4 ligand-1 Property

Boiling point:: 874.1±65.0 °C(Predicted)
Density: 1.68±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 5 mg/mL (9.99 mM)
form: Solid
pka: 3.28±0.20(Predicted)
color: Light yellow to yellow
InChIKey: BSYGSSMAXOMCQE-UHFFFAOYSA-N
SMILES: C1=C2C3C(=CN(C)C(=O)C=3N1)C1=CC(CS(C)(=O)=O)=C(C(O)=O)C=C1N(C1=NC=C(F)C=C1F)C2

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0108581
Product name: PROTACBRD4ligand-1
Purity: 99.50%
Packaging: 5mg
Price: $450
Updated: 2021/12/16

ChemScene

Product number: CS-0108581
Product name: PROTACBRD4ligand-1
Purity: 99.50%
Packaging: 10mg
Price: $750
Updated: 2021/12/16

ChemScene

Product number: CS-0108581
Product name: PROTACBRD4ligand-1
Purity: 99.50%
Packaging: 50mg
Price: $2250
Updated: 2021/12/16

ChemScene

Product number: CS-0108581
Product name: PROTACBRD4ligand-1
Purity: 99.50%
Packaging: 100mg
Price: $3350
Updated: 2021/12/16

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PROTAC BRD4 ligand-1 Chemical Properties,Usage,Production

Uses

PROTAC BRD4 ligand-1 is a potent BET inhibitor and a ligand for target BRD4 protein for PROTACT GNE-987 (HY-129937A)[1].

References

[1] Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2019 Oct 31. DOI:10.1002/cmdc.201900497

PROTAC BRD4 ligand-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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PROTAC BRD4 ligand-1 Suppliers

China 27 United States 2 Global 29

Xirui Biotech (Suzhou) Co., Ltd

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2313230-51-0, PROTAC BRD4 ligand-1Related Search:

PROTAC BRD4 ligand-1

2H-2,4,7-Triazadibenz[cd,f]azulene-9-carboxylic acid, 7-(3,5-difluoro-2-pyridinyl)-3,4,6,7-tetrahydro-2-methyl-10-[(methylsulfonyl)methyl]-3-oxo-

8-(3,5-difluoropyridin-2-yl)-15-methyl-4-(methylsulfonylmethyl)-14-oxo-8,12,15-triazatetracyclo[8.6.1.02,7.013,17]heptadeca-1(16),2(7),3,5,10,13(17)-hexaene-5-carboxylic acid

PROTAC BRD4 ligand 1,PROTAC BRD4 ligand1,PROTAC BRD-4 ligand-1

7-(3,5-difluoropyridin-2-yl)-2-methyl-10-((methylsulfonyl)methyl)-3-oxo-3,4,6,7-tetrahydro-2H-2,4,7-triazadibenzo[cd,f]azulene-9-carboxylic acid

8-(3,5-difluoropyridin-2-yl)-4-(methanesulfonylmethyl)-15-methyl-14-oxo-8,12,15-triazatetracyclo[8.6.1.02,?.013,1?]heptadeca-1(16),2(7),3,5,10,13(17)-hexaene-5-carboxylic acid

7-(3,5-Difluoro-2-pyridyl)-2-methyl-10-[(methylsulfonyl)methyl]-3-oxo-3,4,6,7-tetrahydro-2H-pyrido[3',4':6,7]azepino[3,4,5-cd]isoindole-9-carboxylic Acid

2313230-51-0

C23H18F2N4O5S