Remdesivir impurity
- Product Name
- Remdesivir impurity
- CAS No.
- 1911578-74-9
- Chemical Name
- Remdesivir impurity
- Synonyms
- Remdesivir impurity;Remdesivir Impurity 40;Remdesivir Impurity 46;GS-441524 monophosphate;1,3-dimethyl-7-nitrosourea;RemdesivirImpurity18-13C-d3-15N2;Remdesivir nucleoside monophosphate;Remdesivir Nucleoside Monophosphate Ammonium salt;Remdesivir Impurity 29(Remdesivir nucleoside monophosphate);D-Altrononitrile, 2-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-, 6-(dihydrogen phosphate)
- CBNumber
- CB15832496
- Molecular Formula
- C12H14N5O7P
- Formula Weight
- 371.25
- MOL File
- 1911578-74-9.mol
Remdesivir impurity Property
- Density
- 2.07±0.1 g/cm3(Predicted)
- pka
- 1.86±0.10(Predicted)
- form
- Solid
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- CS-0113740
- Product name
- Remdesivirnucleosidemonophosphate
- Purity
- 99.0%
- Packaging
- 5mg
- Price
- $1200
- Updated
- 2021/12/16
Remdesivir impurity Chemical Properties,Usage,Production
Uses
Remdesivir nucleoside monophosphate is a metabolite of Remdesivir[1]. Remdesivir is a nucleoside analogue with effective antiviral activity against SARS-CoV and MERS-CoV[2].
Definition
ChEBI: GS-441524 monophosphate is a C-nucleoside phosphate that is GS-441524 in which the 5'-hydroxy group has been replaced by a phosphate group. In cells, GS-441524 monophosphate gets converted into the pharmacologically active triphosphate form (GS-443902). It has a role as an anticoronaviral agent, an antiviral drug and a drug metabolite. It is a C-nucleoside phosphate, an aromatic amine, a nitrile and a pyrrolotriazine. It is functionally related to a GS-441524.
References
[1] Byoung Kwon Chun, et al. or treating filoviridae virus infections. US20160122374.
[2] Agostini ML, et al. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease. MBio. 2018 Mar 6;9(2). pii: e00221-18. DOI:10.1128/mBio.00221-18
Remdesivir impurity Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Remdesivir impurity manufacturers
- Product
- Remdesivir Impurity 24 1911578-74-9
- Price
- US $0.00-0.00/mg
- Min. Order
- 10mg
- Purity
- 98
- Supply Ability
- 100000
- Release date
- 2025-02-13