Remdesivir impurity

Product Name: Remdesivir impurity
CAS No.: 1911578-74-9
Chemical Name: Remdesivir impurity
Synonyms: Remdesivir impurity;Remdesivir Impurity 40;Remdesivir Impurity 46;GS-441524 monophosphate;1,3-dimethyl-7-nitrosourea;RemdesivirImpurity18-13C-d3-15N2;Remdesivir nucleoside monophosphate;Remdesivir Nucleoside Monophosphate Ammonium salt;Remdesivir Impurity 29（Remdesivir nucleoside monophosphate）;D-Altrononitrile, 2-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-, 6-(dihydrogen phosphate)
CBNumber: CB15832496
Molecular Formula: C12H14N5O7P
Formula Weight: 371.25
MOL File: 1911578-74-9.mol

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Remdesivir impurity Property

Density: 2.07±0.1 g/cm3(Predicted)
pka: 1.86±0.10(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0113740
Product name: Remdesivirnucleosidemonophosphate
Purity: 99.0%
Packaging: 5mg
Price: $1200
Updated: 2021/12/16

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Remdesivir impurity Chemical Properties,Usage,Production

Uses

Remdesivir nucleoside monophosphate is a metabolite of Remdesivir[1]. Remdesivir is a nucleoside analogue with effective antiviral activity against SARS-CoV and MERS-CoV[2].

Definition

ChEBI: GS-441524 monophosphate is a C-nucleoside phosphate that is GS-441524 in which the 5'-hydroxy group has been replaced by a phosphate group. In cells, GS-441524 monophosphate gets converted into the pharmacologically active triphosphate form (GS-443902). It has a role as an anticoronaviral agent, an antiviral drug and a drug metabolite. It is a C-nucleoside phosphate, an aromatic amine, a nitrile and a pyrrolotriazine. It is functionally related to a GS-441524.

References

[1] Byoung Kwon Chun, et al. or treating filoviridae virus infections. US20160122374.
[2] Agostini ML, et al. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease. MBio. 2018 Mar 6;9(2). pii: e00221-18. DOI:10.1128/mBio.00221-18

Remdesivir impurity Preparation Products And Raw materials

Raw materials

Preparation Products

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Remdesivir impurity Suppliers

China 34 India 3 Global 37

Daicel Chiral Technologies (China)CO.,LTD

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View Lastest Price from Remdesivir impurity manufacturers

Moxin Chemicals

Product: Remdesivir Impurity 24 1911578-74-9
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 98
Supply Ability: 100000
Release date: 2025-02-13

1911578-74-9, Remdesivir impurityRelated Search:

(2S,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol Remdesivir impurity-1 2-ethylbutyl ((R)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate Remdesivir R-18 Remdesivir Impurity 44 R-20 impurity 5 (2R,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol R-19-impurity 4 N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester Remdesivir Impurity 39 (2S)-2-ethylbutyl 2-(((((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate

Remdesivir Impurity 40

Remdesivir nucleoside monophosphate

Remdesivir impurity

D-Altrononitrile, 2-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-, 6-(dihydrogen phosphate)

Remdesivir Impurity 46

Remdesivir Nucleoside Monophosphate Ammonium salt

Remdesivir Phosphate ImpurityQ: What is Remdesivir Phosphate Impurity Q: What is the CAS Number of Remdesivir Phosphate Impurity

Remdesivir Impurity 29（Remdesivir nucleoside monophosphate）

RemdesivirImpurity18-13C-d3-15N2

GS-441524 monophosphate

((2R,3S,4R,5R)-5-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate

1,3-dimethyl-7-nitrosourea

(1R)-1-[(3Ar,4R,6R,6Ar)-6-{4-Amino-7H-Pyrrolo[2,3-D]Pyrimidin-7-Yl}-2,2,6A-Trimethyl-Tetrahydro-2H-Furo[3,4-D][1,3]Dioxol-4-Yl]Ethan-1-Ol

1911578-74-9

2257421-79-6

73486-81-5