FAPI-4

Product Name: FAPI-4
CAS No.: 2374782-02-0
Chemical Name: FAPI-4
Synonyms: FAPI;187366;FAPI-4;FAPI04;G-1002;DOTA-FAPI4;DOTA-FAPI 04;FAPI-4 Chemical Structure;1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, 10-[2-[4-[3-[[4-[[[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]amino]carbonyl]-6-quinolinyl]oxy]propyl]-1-piperazinyl]-2-oxoethyl]-;(S)-2,2’,2’’-[10-[2-[4-[3-[[4-[[2-(2-Cyano-4,4-difluoro-1-pyrrolidinyl)-2-oxoethyl]carbamoyl]-6-quinolyl]oxy]propyl]-1-piperazinyl]-2-oxoethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triyl]triacetic Acid
CBNumber: CB15849362
Molecular Formula: C40H54F2N10O10
Formula Weight: 872.93
MOL File: 2374782-02-0.mol

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FAPI-4 Property

Boiling point:: 1144.1±65.0 °C(Predicted)
Density: 1.46±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 100 mg/mL (114.56 mM)
pka: 1.83±0.10(Predicted)
form: Solid
color: White to off-white
InChIKey: ICWDAESAANBIGG-NNFJEGBSNA-N
SMILES: C(C1=CC=NC2C=CC(OCCCN3CCN(C(=O)CN4CCN(CCN(CC(=O)O)CCN(CC(=O)O)CC4)CC(=O)O)CC3)=CC1=2)(=O)NCC(N1CC(F)(F)C[C@H]1C#N)=O |&1:58,r|

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Hazard and Precautionary Statements (GHS)

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FAPI-4 Chemical Properties,Usage,Production

Uses

FAPI-4 is a substituted pyrrolidinyloxoethyl quinolinecarboxamides and one type of theranostic ligand for fibroblast activation protein (FAP). FAPI-4 is a FAP inhibitor (FAPI) and has been studied for its pharmaceutical properties in the diagnose or treatment of diseases driven by the overexpression of FAPs.

in vivo

FAPI-4 (Intravenous injection; 30 nmol per mouse; once) shows excellent tumor uptake in BALB/c nu/nu mice^[2].

Animal Model:	8-week-old BALB/c nu/nu mice inoculated with HT-1080-FAP cells^[2]
Dosage:	30 nmol per mouse
Administration:	Intravenous injection; 30 nmol per mouse; once
Result:	Revealed the high overall tumor uptake (9.44%ID/g 4 h after injection).

FAPI-4 Preparation Products And Raw materials

Raw materials

Preparation Products

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FAPI-4 Suppliers

China 40 United States 4 Global 44

Nanchang Tianzhen Biotechnology Co., Ltd

Tel: 13758194781 13173652190
Email: 522013271@qq.com
Country: China
ProdList: 2395
Advantage: 58

Hangzhou Baige Pharmaceutical Technology Co. , Ltd.

Tel: 0571-85350119 15888826472
Email: 15888826472@163.com
Country: China
ProdList: 2729
Advantage: 58

Hangzhou Beiputai Biopharmaceutical Co., Ltd

Tel: 0571-85350119 15888826472
Email: bptsales@163.com
Country: China
ProdList: 3834
Advantage: 58

Tetranov Biopharm

Tel: 13526569071
Email: sales@leadmedpharm.com
Country: China
ProdList: 7892
Advantage: 64

YangZhou Ruihong Biotech Co., Ltd.

Tel: 0514-015380367604 15380367604
Fax: 0514-83828236
Email: sales@ruibobiotech.com
Country: China
ProdList: 511
Advantage: 55

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3506
Advantage: 58

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 15873
Advantage: 55

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4769
Advantage: 55

Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
Fax: 022-23754520
Email: klq@cw-bio.com
Country: China
ProdList: 8011
Advantage: 55

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 9125
Advantage: 58

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View Lastest Price from FAPI-4 manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: FAPI-4 2374782-02-0
Price: US $0.00/mg
Min. Order: 10mg
Purity: >95.00%
Supply Ability: 10mg
Release date: 2024-04-01

2374782-02-0, FAPI-4Related Search:

FAPI-4

187366

(S)-2,2',2''-(10-(2-(4-(3-((4-((2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamoyl)quinolin-6-yl)oxy)propyl)piperazin-1-yl)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetic acid

FAPI04

(S)-2,2’,2’’-[10-[2-[4-[3-[[4-[[2-(2-Cyano-4,4-difluoro-1-pyrrolidinyl)-2-oxoethyl]carbamoyl]-6-quinolyl]oxy]propyl]-1-piperazinyl]-2-oxoethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triyl]triacetic Acid

FAPI

G-1002

FAPI-4 Chemical Structure

1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, 10-[2-[4-[3-[[4-[[[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]amino]carbonyl]-6-quinolinyl]oxy]propyl]-1-piperazinyl]-2-oxoethyl]-

DOTA-FAPI4

DOTA-FAPI 04

2374782-02-0

C40H54F2N10O10