ChemicalBook > CAS DataBase List > 2-(1H-IMIDAZOL-2-YL)-PYRIDINE

2-(1H-IMIDAZOL-2-YL)-PYRIDINE

Product Name
2-(1H-IMIDAZOL-2-YL)-PYRIDINE
CAS No.
18653-75-3
Chemical Name
2-(1H-IMIDAZOL-2-YL)-PYRIDINE
Synonyms
DK7401;2-(2-Pyridyl)imidazole;2-(2′-Pyridyl)imidazole;2-(2-Imidazolyl)pyridine;2-(Pyridin-2-yl)imidazole;2-(Imidazol-2-yl)pyridine;2-(Pyridyl-2-yl)imidazole;2-(imidazole-2-yl)pyridine;2-(1H-lmidazol-2-yl)pyridine;2-(1H-IMIDAZOL-2-YL)-PYRIDINE
CBNumber
CB1667169
Molecular Formula
C8H7N3
Formula Weight
145.16
MOL File
18653-75-3.mol
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2-(1H-IMIDAZOL-2-YL)-PYRIDINE Property

Melting point:
135-140°C
Boiling point:
382.8±15.0 °C(Predicted)
Density 
1.214±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Slightly), DMSO (Slightly)
pka
pK1:8.98(+1) (25°C,μ=0.005)
form 
solid
color 
Light brown to yellow
InChI
InChI=1S/C8H7N3/c1-2-4-9-7(3-1)8-10-5-6-11-8/h1-6H,(H,10,11)
InChIKey
SZXUTTGMFUSMCE-UHFFFAOYSA-N
SMILES
C1(C2NC=CN=2)=NC=CC=C1
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Safety

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
739405
Product name
2-(1H-Imidazol-2-yl)pyridine
Purity
97%
Packaging
5g
Price
$277.2
Updated
2025/07/31
TCI Chemical
Product number
I1203
Product name
2-(1H-Imidazol-2-yl)pyridine
Purity
min. 98.0 %
Packaging
1G
Price
$91
Updated
2025/07/31
TRC
Product number
P995380
Product name
2-(2-Pyridyl)imidazole
Packaging
250mg
Price
$45
Updated
2021/12/16
TRC
Product number
P995380
Product name
2-(2-Pyridyl)imidazole
Packaging
5g
Price
$370
Updated
2021/12/16
Apolloscientific
Product number
OR962208
Product name
2-(1H-Imidazol-2-yl)pyridine
Purity
98%
Packaging
1g
Price
$85
Updated
2021/12/16
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2-(1H-IMIDAZOL-2-YL)-PYRIDINE Chemical Properties,Usage,Production

Uses

2-(2-Pyridyl)imidazole is a useful reagent in substitution reaction with bromobenzene.

Synthesis

7471-05-8

18653-75-3

General procedure for the synthesis of 2-(imidazol-2-yl)pyridine from 2-(4,5-dihydro-1H-imidazol-2-yl)pyridine: a generalized method of [Mn(TPP)Cl]-catalyzed dehydrogenation of imidazolines with NaIO4 was used. All reactions were carried out at room temperature and air atmosphere in a 25 mL round bottom flask equipped with a magnetic stir bar. To a solution of CH3CN (5 mL) containing 2-imidazoline (1 mmol) and [Mn(TPP)Cl] (0.05 mmol), a solution of NaIO4 (2 mmol) in H2O (10 mL) was added. The reaction process was monitored by thin layer chromatography (TLC) (eluent: EtOAc/MeOH, 4:1). After completion of the reaction, water (30 mL) was added and the target product imidazole was extracted with CH2Cl2 (2 x 20 mL). After evaporation of the solvent, the imidazole derivative was obtained. The structure of the product was confirmed by infrared spectroscopy (IR) and 1H nuclear magnetic resonance (1H NMR) data.

References

[1] Synlett, 2004, # 15, p. 2803 - 2805
[2] Transition Metal Chemistry, 2013, vol. 38, # 1, p. 1 - 5
[3] Canadian Journal of Chemistry, 2005, vol. 83, # 2, p. 110 - 114
[4] Tetrahedron Letters, 2004, vol. 45, # 47, p. 8687 - 8690
[5] Polyhedron, 2011, vol. 30, # 9, p. 1463 - 1468

2-(1H-IMIDAZOL-2-YL)-PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-(1H-IMIDAZOL-2-YL)-PYRIDINE manufacturers

Career Henan Chemical Co
Product
2-(1H-IMIDAZOL-2-YL)-PYRIDINE 18653-75-3
Price
US $3.00/KG
Min. Order
1KG
Purity
90%-99.9%
Supply Ability
1000kg
Release date
2019-07-04

18653-75-3, 2-(1H-IMIDAZOL-2-YL)-PYRIDINERelated Search:


  • 2-(1H-IMIDAZOL-2-YL)-PYRIDINE
  • 2-(1H-imidazol-2-yl)pyridine(SALTDATA: FREE)
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  • Pyridine, 2-(1H-iMidazol-2-yl)-
  • 2-(1<I>H</I>-<WBR>IMidazol-<WBR>2-<WBR>yl)<WBR>pyridine
  • 2-(2′-Pyridyl)imidazole
  • 2-(2-Pyridyl)imidazole
  • 2-(Pyridin-2-yl)imidazole
  • Pyridine,2-imidazol-2-yl- (8Cl)
  • 2-(2-Imidazolyl)pyridine
  • 2-(1<I>H</I>-Imidazol-2-yl)pyridine
  • 2-(Pyridyl-2-yl)imidazole
  • 2-(1H-lmidazol-2-yl)pyridine
  • 2-(1H-Imidazol-2-yl)pyridine 97%
  • DK7401
  • 2-(imidazole-2-yl)pyridine
  • 18653-75-3