5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE

Product Name: 5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE
CAS No.: 27406-31-1
Chemical Name: 5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE
Synonyms: MHY-1685;IFLAB-BB F1208-0006;MHY-1685, 10 mM in DMSO;5-(4-HYDROXYBENZYLIDENE)BARBITURIC ACID;5-(4-HYDROXYBENZYLIDENE)BARBUTIRIC ACID;5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE;5-(4-HYDROXYBENZYLIDENE)PYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE;5-(4-hydroxyphenyl)methylenehexahydropyrimidine-2,4,6-trione;2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(4-hydroxyphenyl)methylene]-;MHY-1685,MHY1685,MHY 1685,inhibit,mTOR,Inhibitor,Mammalian target of Rapamycin
CBNumber: CB1669325
Molecular Formula: C11H8N2O4
Formula Weight: 232.19
MOL File: Mol file

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5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE Property

storage temp.: Store at -20°C
solubility: DMSO : 62.5 mg/mL (269.18 mM; Need ultrasonic)
form: Solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S135925
Product name: 5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE
Purity: Aldrich<sup>CPR</sup>
Packaging: 1 unit
Price: $30.7
Updated: 2025/07/31

Sigma-Aldrich

Product number: S135925
Product name: 5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE
Purity: Aldrich
Packaging: 50mg
Price: $29.8
Updated: 2024/03/01

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5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE Chemical Properties,Usage,Production

Uses

MHY-1685, a novel mammalian target of rapamycin (mTOR) inhibitor, provides opportunities to improve hCSC-based myocardial regeneration.

Biological Activity

MHY-1685, a novel mammalian target of rapamycin (mTOR) inhibitor, provides opportunities to improve hCSC-based myocardial regeneration.

References

[1]. Park JH, et al. Human cardiac stem cells rejuvenated by modulating autophagy with MHY-1685 enhance the therapeutic potential for cardiac repair. Exp Mol Med. 2021 Sep;53(9):1423-1436.

5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE Suppliers

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27406-31-1, 5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONERelated Search:

IFLAB-BB F1208-0006

5-(4-HYDROXYBENZYLIDENE)BARBITURIC ACID

5-(4-HYDROXYBENZYLIDENE)PYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE

5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE

5-(4-HYDROXYBENZYLIDENE)BARBUTIRIC ACID

2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(4-hydroxyphenyl)methylene]-

5-(4-hydroxyphenyl)methylenehexahydropyrimidine-2,4,6-trione

MHY-1685

MHY-1685,MHY1685,MHY 1685,inhibit,mTOR,Inhibitor,Mammalian target of Rapamycin

MHY-1685, 10 mM in DMSO

27406-31-1