ChemicalBook > CAS DataBase List > 5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE

5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE

Product Name
5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE
CAS No.
27406-31-1
Chemical Name
5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE
Synonyms
MHY-1685;IFLAB-BB F1208-0006;5-(4-HYDROXYBENZYLIDENE)BARBITURIC ACID;5-(4-HYDROXYBENZYLIDENE)BARBUTIRIC ACID;5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE;5-(4-HYDROXYBENZYLIDENE)PYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE;5-(4-hydroxyphenyl)methylenehexahydropyrimidine-2,4,6-trione;2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(4-hydroxyphenyl)methylene]-;MHY-1685,MHY1685,MHY 1685,inhibit,mTOR,Inhibitor,Mammalian target of Rapamycin
CBNumber
CB1669325
Molecular Formula
C11H8N2O4
Formula Weight
232.19
MOL File
Mol file
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5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE Property

storage temp. 
Store at -20°C
solubility 
DMSO : 62.5 mg/mL (269.18 mM; Need ultrasonic)
form 
Solid
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S135925
Product name
5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE
Purity
Aldrich
Packaging
50mg
Price
$29.8
Updated
2024/03/01
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5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE Chemical Properties,Usage,Production

Biological Activity

MHY-1685, a novel mammalian target of rapamycin (mTOR) inhibitor, provides opportunities to improve hCSC-based myocardial regeneration.

References

[1]. Park JH, et al. Human cardiac stem cells rejuvenated by modulating autophagy with MHY-1685 enhance the therapeutic potential for cardiac repair. Exp Mol Med. 2021 Sep;53(9):1423-1436.

5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE Suppliers

Canada 1 China 18 India 1 United Kingdom 1 United States 5 Global 26
Nanjing Chalf-Pharm Technology Co., Ltd.
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27406-31-1, 5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONERelated Search:


  • IFLAB-BB F1208-0006
  • 5-(4-HYDROXYBENZYLIDENE)BARBITURIC ACID
  • 5-(4-HYDROXYBENZYLIDENE)PYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE
  • 5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE
  • 5-(4-HYDROXYBENZYLIDENE)BARBUTIRIC ACID
  • 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(4-hydroxyphenyl)methylene]-
  • 5-(4-hydroxyphenyl)methylenehexahydropyrimidine-2,4,6-trione
  • MHY-1685
  • MHY-1685,MHY1685,MHY 1685,inhibit,mTOR,Inhibitor,Mammalian target of Rapamycin
  • 27406-31-1