A-18-F-NH2

Product Name: A-18-F-NH2
CAS No.: 99588-52-0
Chemical Name: A-18-F-NH2
Synonyms: A18Famide;A-18-F-NH2;PubChem ID: 16131005;Morphine Modulating Neuropeptide;ALA-GLY-GLU-GLY-LEU-SER-SER-PRO-PHE-TRP-SER-LEU-ALA-ALA-PRO-GLN-ARG-PHE-NH2;H-ALA-GLY-GLU-GLY-LEU-SER-SER-PRO-PHE-TRP-SER-LEU-ALA-ALA-PRO-GLN-ARG-PHE-NH2;ALA-GLY-GLU-GLY-LEU-SER-SER-PRO-PHE-TRP-SER-LEU-ALA-ALA-PRO-GLN-ARG-PHE AMIDE;A-18-F-NH2;H-ALA-GLY-GLU-GLY-LEU-SER-SER-PRO-PHE-TRP-SER-LEU-ALA-ALA-PRO-GLN-ARG-PHE-NH2;L-Phenylalaninamide, L-alanylglycyl-L-α-glutamylglycyl-L-leucyl-L-seryl-L-seryl-L-prolyl-L-phenylalanyl-L-tryptophyl-L-seryl-L-leucyl-L-alanyl-L-alanyl-L-prolyl-L-glutaminyl-L-arginyl-
CBNumber: CB1682771
Molecular Formula: C89H130N24O24
Formula Weight: 1920.13
MOL File: 99588-52-0.mol

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A-18-F-NH2 Property

Density: 1.48±0.1 g/cm3(Predicted)
storage temp.: -15°C
pka: 4.43±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological

Product number: M4675-01A
Product name: Morphine Modulating Neuropeptide
Packaging: 1mg
Price: $531
Updated: 2021/12/16

Usbiological

Product number: M4675-01
Product name: Morphine Modulating Neuropeptide
Packaging: 1mg
Price: $531
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0009156
Product name: A-18-F-NH2
Purity: 95.00%
Packaging: 0.5MG
Price: $599.5
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0009156
Product name: A-18-F-NH2
Purity: 95.00%
Packaging: 1MG
Price: $664.13
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb71317
Product name: Morphine Modulating Neuro peptide
Purity: Greater than 85% affinity purified
Packaging: 5mg
Price: $425
Updated: 2021/12/16

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A-18-F-NH2 Chemical Properties,Usage,Production

Uses

Neuropeptide AF (cattle), an amidated octadecapeptide, is RFamide neuropeptide. Neuropeptide AF (cattle) acts as a ligand of Mas-related gene receptor A4 (MrgprA4) (Mas-related G-protein-coupled Receptor (MRGPR)) (EC50 of ~60 nM) and MrgprC11 (EC50 of ~300 nM). Neuropeptide AF (cattle) also activate to the G protein-coupled receptors NPFF1 (Neuropeptide Y Receptor) (EC50 of ~25-325 nM) and NPFF2 (EC50 of ~1-5 nM). Neuropeptide AF (cattle) shows anti-opiate and related pain modulation effects[1][2].

in vivo

Neuropeptide AF (cattle) (0.25 μg/2 μL; i.c.v.; 30 min prior to the tests) decreases the immobility time and increases the climbing and swimming times in modified mouse forced swimming test (mFST)^[2].

Animal Model:	Male CFLP mice (25-28 g)^[2]
Dosage:	0.25 μg/2 μL
Administration:	i.c.v.; 30 min prior to the tests
Result:	Decreased the immobility time and increased the climbing and swimming times.

References

[1] Nada Abdellah, et al. Neuropeptide AF Induces Piecemeal Degranulation in Murine Mucosal Mast Cells: A New Mediator in Neuro-Immune Communication in the Intestinal Lamina Propria? Anat Rec (Hoboken). 2018 Jun;301(6):1103-1114. DOI:10.1002/ar.23780
[2] Miklós Palotai, et al. Neuropeptide AF induces anxiety-like and antidepressant-like behavior in mice. Behav Brain Res. 2014 Nov 1;274:264-9. DOI:10.1016/j.bbr.2014.08.007

A-18-F-NH2 Preparation Products And Raw materials

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A-18-F-NH2 Suppliers

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99588-52-0, A-18-F-NH2Related Search:

ALA-PRO-GLY-TRP-NH2 ACETATE SALT A-18-F-NH2

A-18-F-NH2

ALA-GLY-GLU-GLY-LEU-SER-SER-PRO-PHE-TRP-SER-LEU-ALA-ALA-PRO-GLN-ARG-PHE AMIDE

ALA-GLY-GLU-GLY-LEU-SER-SER-PRO-PHE-TRP-SER-LEU-ALA-ALA-PRO-GLN-ARG-PHE-NH2

H-ALA-GLY-GLU-GLY-LEU-SER-SER-PRO-PHE-TRP-SER-LEU-ALA-ALA-PRO-GLN-ARG-PHE-NH2

A18Famide

A-18-F-NH2;H-ALA-GLY-GLU-GLY-LEU-SER-SER-PRO-PHE-TRP-SER-LEU-ALA-ALA-PRO-GLN-ARG-PHE-NH2

Morphine Modulating Neuropeptide

PubChem ID: 16131005

L-Phenylalaninamide, L-alanylglycyl-L-α-glutamylglycyl-L-leucyl-L-seryl-L-seryl-L-prolyl-L-phenylalanyl-L-tryptophyl-L-seryl-L-leucyl-L-alanyl-L-alanyl-L-prolyl-L-glutaminyl-L-arginyl-

99588-52-0

C89H130N24O24