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BENZYL CIS-4-AMINOCYCLOHEXYLCARBAMATE

Product Name
BENZYL CIS-4-AMINOCYCLOHEXYLCARBAMATE
CAS No.
149423-70-1
Chemical Name
BENZYL CIS-4-AMINOCYCLOHEXYLCARBAMATE
Synonyms
Benzyl (cis-4-aminocyclohexyl);cis-N-Cbz-1,4-cyclohexanediaMine;N-Cbz-cis-1,4-cyclohexanediamine;CIS-1-N-CBZ-1,4-CYCLOHEXYLDIAMINE;1-N-CBZ-CIS-1,4-CYCLOHEXYLDIAMINE;Trans-1N-Cbz-cyclohexane-1,4-diaMine;BENZYL CIS-4-AMINOCYCLOHEXYLCARBAMATE;benzyl (1s,4s)-4-aminocyclohexylcarbamate;cis-4-(Benzyloxycarbonylamino)cyclohexylamine;cis-4-(BenzyloxycarbonylaMino)cyclohexylaMine, 97%
CBNumber
CB1691616
Molecular Formula
C14H20N2O2
Formula Weight
248.32
MOL File
149423-70-1.mol
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BENZYL CIS-4-AMINOCYCLOHEXYLCARBAMATE Property

Boiling point:
409.5±44.0 °C(Predicted)
Density 
1.13±0.1 g/cm3(Predicted)
pka
12.23±0.40(Predicted)
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Safety

HS Code 
2924297099
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

TRC
Product number
B233800
Product name
Benzylcis-4-aminocyclohexylcarbamate
Packaging
250mg
Price
$60
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB56992
Product name
Benzyl (cis-4-aminocyclohexyl)carbamate
Packaging
50mg
Price
$63
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB56992
Product name
Benzyl (cis-4-aminocyclohexyl)carbamate
Packaging
100mg
Price
$101
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB56992
Product name
Benzyl (cis-4-aminocyclohexyl)carbamate
Packaging
250mg
Price
$125
Updated
2021/12/16
Matrix Scientific
Product number
089463
Product name
Benzyl cis-4-aminocyclohexylcarbamate
Packaging
1g
Price
$198
Updated
2021/12/16
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BENZYL CIS-4-AMINOCYCLOHEXYLCARBAMATE Chemical Properties,Usage,Production

Synthesis

509143-03-7

149423-70-1

Step B: Synthesis of cis-(4-amino-cyclohexyl)-carbamic acid benzyl ester. To a solution of cis-(4-tert-butoxycarbonylamino-cyclohexyl)-carbamic acid benzyl ester (6.2 g, 0.018 mol) in dichloromethane (40 mL) was added trifluoroacetic acid (2.7 mL, 0.36 mol). The reaction mixture was stirred at room temperature for 4 hours. Upon completion of the reaction, the excess solvent was removed by rotary evaporation and the resulting oil was dissolved in dichloromethane (30 mL). The organic layer was extracted with dilute aqueous sodium hydroxide/aqueous sodium bicarbonate solution (30 mL). The aqueous layer was back-extracted twice with dichloromethane, and the organic layers were combined, dried over anhydrous magnesium sulfate, and concentrated to give cis-(4-amino-cyclohexyl)-carbamic acid benzyl ester (4.3 g, 97%) as a colorless oil. The product was used directly in the next reaction without further purification.ESI MS m/z 249.2 [M + H]+.

References

[1] Patent: EP1464335, 2004, A2. Location in patent: Page/Page column 293

BENZYL CIS-4-AMINOCYCLOHEXYLCARBAMATE Preparation Products And Raw materials

Raw materials

Preparation Products

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BENZYL CIS-4-AMINOCYCLOHEXYLCARBAMATE Suppliers

J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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China
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Alfa Aesar
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400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
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Tel
+86 (0) 571 85 58 67 18
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Tetranov Biopharm
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Shanghai Sunway Pharmaceutical Technology Co., Ltd
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021 51613951
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Nanjing Norris-Pharm Technology Co., Ltd
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Shanghai Yolne Chemical Co., Ltd.
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149423-70-1, BENZYL CIS-4-AMINOCYCLOHEXYLCARBAMATERelated Search:


  • BENZYL CIS-4-AMINOCYCLOHEXYLCARBAMATE
  • 1-N-CBZ-CIS-1,4-CYCLOHEXYLDIAMINE
  • cis-N-Cbz-1,4-cyclohexanediaMine
  • cis-4-(BenzyloxycarbonylaMino)cyclohexylaMine, 97%
  • Trans-1N-Cbz-cyclohexane-1,4-diaMine
  • Benzyl (cis-4-aminocyclohexyl)
  • CIS-1-N-CBZ-1,4-CYCLOHEXYLDIAMINE
  • benzyl (1s,4s)-4-aminocyclohexylcarbamate
  • N-(4-aminocyclohexyl)carbamic acid (phenylmethyl) ester
  • Carbamic acid, N-(cis-4-aminocyclohexyl)-, phenylmethyl ester
  • N-Cbz-cis-1,4-cyclohexanediamine
  • cis-4-(Benzyloxycarbonylamino)cyclohexylamine
  • 149423-70-1
  • Heterocycles series