Hydroxyecdysone
- Product Name
- Hydroxyecdysone
- CAS No.
- 5289-74-7
- Chemical Name
- Hydroxyecdysone
- Synonyms
- ECDYSTERONE;20-HYDROXYECDYSONE;β-Ecdysterone;BETA-ECDYSTERONE;crustecdysone;ecdysteron;BETA-ECDYSONE;β-Ecdysone;B-ECDYSONE;the-7
- CBNumber
- CB1692996
- Molecular Formula
- C27H44O7
- Formula Weight
- 480.64
- MOL File
- 5289-74-7.mol
Hydroxyecdysone Property
- Melting point:
- 242-244 °C
- Boiling point:
- 498.63°C (rough estimate)
- Density
- 1.0760 (rough estimate)
- refractive index
- 1.5800 (estimate)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- alcohol: soluble
- form
- powder
- pka
- 14.13±0.70(Predicted)
- color
- white
- Merck
- 13,3525
- BRN
- 1917578
- InChI
- InChI=1/C27H44O7/c1-23(2,32)9-8-22(31)26(5,33)21-7-11-27(34)16-12-18(28)17-13-19(29)20(30)14-24(17,3)15(16)6-10-25(21,27)4/h12,15,17,19-22,29-34H,6-11,13-14H2,1-5H3/t15-,17-,19+,20-,21-,22+,24+,25+,26+,27+/s3
- InChIKey
- NKDFYOWSKOHCCO-YPVLXUMRSA-N
- SMILES
- O[C@@]12CC[C@]([H])([C@](O)(C)[C@H](O)CCC(O)(C)C)[C@]1(CC[C@]1([H])[C@]3(C[C@H](O)[C@H](O)C[C@@]3([H])C(=O)C=C21)C)C |&1:1,4,6,9,17,20,22,24,26,29,r|
- LogP
- -0.270 (est)
- CAS DataBase Reference
- 5289-74-7(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 22-24/25-36-26
- WGK Germany
- 2
- RTECS
- FZ8060000
- F
- 10
- HS Code
- 29372900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P273Avoid release to the environment.
P391Collect spillage. Hazardous to the aquatic environment
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- H5142
- Product name
- 20-Hydroxyecdysone
- Purity
- ≥93% (HPLC), powder
- Packaging
- 5mg
- Price
- $196
- Updated
- 2024/03/01
- Product number
- H5142
- Product name
- 20-Hydroxyecdysone
- Purity
- ≥93% (HPLC), powder
- Packaging
- 10mg
- Price
- $357
- Updated
- 2024/03/01
- Product number
- J63091
- Product name
- Ecdysterone
- Packaging
- 10mg
- Price
- $213.65
- Updated
- 2024/03/01
- Product number
- J63091
- Product name
- Ecdysterone
- Packaging
- 50mg
- Price
- $768.65
- Updated
- 2024/03/01
- Product number
- 16145
- Product name
- 20-hydroxy Ecdysone
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $49
- Updated
- 2024/03/01
Hydroxyecdysone Chemical Properties,Usage,Production
Chemical Properties
White or off-white powder, odorless, hygroscopic, the color gradually becomes darker when exposed to light. Soluble in ethanol, slightly soluble in acetone, slightly soluble in hot water, ethyl acetate, chloroform, almost insoluble in ether, derived from Leulu, Achyranthes bidentata, Cyanotis, arachnoidea, Pfaffia glomerata.
Uses
20-Hydroxyecdysone has been used:
in Leibovitz′s dissecting medium for culturing sorting zone and neuropil-associated glia and antennal lobes of Manduca sexta
in Schneider′s medium to reproduce ex-vivo imaginal disc eversion
as a supplement in Mcl8 medium for culturing Drosophila wing imaginal discs
as an insect molting hormone
Definition
ChEBI: 20-hydroxyecdysone is an ecdysteroid that is ecdysone substituted by a hydroxy group at position 20. It has a role as a plant metabolite and an animal metabolite. It is a 20-hydroxy steroid, an ecdysteroid, a 14alpha-hydroxy steroid, a 3beta-sterol, a 2beta-hydroxy steroid, a 22-hydroxy steroid, a 25-hydroxy steroid and a phytoecdysteroid. It is functionally related to an ecdysone.
Biochem/physiol Actions
20-Hydroxyecdysone is an ecdysteroid hormone that plays a key role in insect development, cell proliferaton, growth and apoptosis by controlling gene expression involved in molting and metamorphosis. It acts through a heterodimeric receptor comprising the ecdysone receptor and the ultraspiracle proteins (USP).
storage
+4°C
Purification Methods
Crystallise -ecdyson from water, tetrahydrofuran/pet ether, MeOH and EtOAc after chromatographic purification. It has max (EtOH) at 240nm ( 12,670 M-1cm-1). [Also IR & NMR: Hüppi & Siddall J Am Chem Soc 89 6799 1967, Kametani et al. Tetrahedron Lett 21 4855 1980, Beilstein 8 IV 343.]
Hydroxyecdysone Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Hydroxyecdysone manufacturers
- Product
- 20-Hydroxyecdysone 5289-74-7
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1Kg
- Purity
- 98%HPLC
- Supply Ability
- 1 ton
- Release date
- 2024-11-07
- Product
- Ecdysone / Ecdysterone 5289-74-7
- Price
- US $180.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-04-23
- Product
- Hydroxyecdysone 5289-74-7
- Price
- US $0.00/KG
- Min. Order
- 2KG
- Purity
- 98% up, High Density
- Supply Ability
- 20 tons
- Release date
- 2024-02-29