Hydroxyecdysone

Product Name: Hydroxyecdysone
CAS No.: 5289-74-7
Chemical Name: Hydroxyecdysone
Synonyms: ECDYSTERONE;20-HYDROXYECDYSONE;β-Ecdysterone;BETA-ECDYSTERONE;crustecdysone;ecdysteron;BETA-ECDYSONE;β-Ecdysone;B-ECDYSONE;the-7
CBNumber: CB1692996
Molecular Formula: C27H44O7
Formula Weight: 480.64
MOL File: 5289-74-7.mol

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Hydroxyecdysone Property

Melting point:: 242-244 °C
Boiling point:: 498.63°C (rough estimate)
Density: 1.0760 (rough estimate)
refractive index: 1.5800 (estimate)
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: alcohol: soluble
form: powder
pka: 14.13±0.70(Predicted)
color: white
Merck: 13,3525
BRN: 1917578
InChI: InChI=1/C27H44O7/c1-23(2,32)9-8-22(31)26(5,33)21-7-11-27(34)16-12-18(28)17-13-19(29)20(30)14-24(17,3)15(16)6-10-25(21,27)4/h12,15,17,19-22,29-34H,6-11,13-14H2,1-5H3/t15-,17-,19+,20-,21-,22+,24+,25+,26+,27+/s3
InChIKey: NKDFYOWSKOHCCO-YPVLXUMRSA-N
SMILES: O[C@@]12CC[C@]([H])([C@](O)(C)[C@H](O)CCC(O)(C)C)[C@]1(CC[C@]1([H])[C@]3(C[C@H](O)[C@H](O)C[C@@]3([H])C(=O)C=C21)C)C |&1:1,4,6,9,17,20,22,24,26,29,r|
LogP: -0.270 (est)
CAS DataBase Reference: 5289-74-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 22-24/25-36-26
WGK Germany: 2
RTECS: FZ8060000
F: 10
HS Code: 29372900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: H5142
Product name: 20-Hydroxyecdysone
Purity: ≥93% (HPLC), powder
Packaging: 5mg
Price: $196
Updated: 2024/03/01

Sigma-Aldrich

Product number: H5142
Product name: 20-Hydroxyecdysone
Purity: ≥93% (HPLC), powder
Packaging: 10mg
Price: $357
Updated: 2024/03/01

Alfa Aesar

Product number: J63091
Product name: Ecdysterone
Packaging: 10mg
Price: $213.65
Updated: 2024/03/01

Alfa Aesar

Product number: J63091
Product name: Ecdysterone
Packaging: 50mg
Price: $768.65
Updated: 2024/03/01

Cayman Chemical

Product number: 16145
Product name: 20-hydroxy Ecdysone
Purity: ≥98%
Packaging: 5mg
Price: $49
Updated: 2024/03/01

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Hydroxyecdysone Chemical Properties,Usage,Production

Chemical Properties

White or off-white powder, odorless, hygroscopic, the color gradually becomes darker when exposed to light. Soluble in ethanol, slightly soluble in acetone, slightly soluble in hot water, ethyl acetate, chloroform, almost insoluble in ether, derived from Leulu, Achyranthes bidentata, Cyanotis, arachnoidea, Pfaffia glomerata.

Uses

20-Hydroxyecdysone has been used:
in Leibovitz′s dissecting medium for culturing sorting zone and neuropil-associated glia and antennal lobes of Manduca sexta
in Schneider′s medium to reproduce ex-vivo imaginal disc eversion
as a supplement in Mcl8 medium for culturing Drosophila wing imaginal discs
as an insect molting hormone

Definition

ChEBI: 20-hydroxyecdysone is an ecdysteroid that is ecdysone substituted by a hydroxy group at position 20. It has a role as a plant metabolite and an animal metabolite. It is a 20-hydroxy steroid, an ecdysteroid, a 14alpha-hydroxy steroid, a 3beta-sterol, a 2beta-hydroxy steroid, a 22-hydroxy steroid, a 25-hydroxy steroid and a phytoecdysteroid. It is functionally related to an ecdysone.

Biochem/physiol Actions

20-Hydroxyecdysone is an ecdysteroid hormone that plays a key role in insect development, cell proliferaton, growth and apoptosis by controlling gene expression involved in molting and metamorphosis. It acts through a heterodimeric receptor comprising the ecdysone receptor and the ultraspiracle proteins (USP).

storage

+4°C

Purification Methods

Crystallise -ecdyson from water, tetrahydrofuran/pet ether, MeOH and EtOAc after chromatographic purification. It has max (EtOH) at 240nm ( 12,670 M-1cm-1). [Also IR & NMR: Hüppi & Siddall J Am Chem Soc 89 6799 1967, Kametani et al. Tetrahedron Lett 21 4855 1980, Beilstein 8 IV 343.]

Hydroxyecdysone Preparation Products And Raw materials

Raw materials

Preparation Products

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Hydroxyecdysone Suppliers

Canada 3 China 443 Czech Republic 1 Europe 3 France 2 Germany 3 India 4 Japan 2 Poland 1 Switzerland 3 United Kingdom 16 United States 48 Global 529

Kono Chem Co.,Ltd

Tel: 029-86107037-8009 13279399072
Fax: 13279399072
Email: info@konochemical.com
Country: China
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Advantage: 58

Shaanxi Pioneer Biotech Co.,Ltd

Tel: 18629309720
Email: sales@pioneerbiotech.com
Country: China
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Shaanxi Pioneer Biotech Co.,Ltd

Tel: 029-84385017-8007 17602929471
Email: sales11@pioneerbiotech.com
Country: China
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Shaanxi Pioneer Biotech Co.,Ltd.

Tel: 029-84385017-8011 15202491660
Fax: QQ3502078241
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Country: China
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Shaanxi Pioneer Biotech Co., Ltd.

Tel: 13720616393；029-84385017-8003 13720616393
Fax: 029-84385017
Email: sales@pioneerbiotech.com
Country: China
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Xi'an Jianglin Biotechnology Co., Ltd

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Email: JLSW00@163.com
Country: China
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Hubei Chenghai Chemical Co., Ltd

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Country: China
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J & K SCIENTIFIC LTD.

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Jiangsu Huayu Chemical Co., Ltd.

Tel: 25-83241163
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3B Pharmachem (Wuhan) International Co.,Ltd.

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Fax: 86-21-50328109
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View Lastest Price from Hydroxyecdysone manufacturers

Hebei Dangtong Import and export Co LTD

Product: Hydroxyecdysone 5289-74-7
Price: US $2470.00-2460.00/kg
Min. Order: 1kg
Purity: 99.99%
Supply Ability: 100Tons
Release date: 2023-03-03

Wuhan Haorong Biotechnology Co.,Ltd

Product: Hydroxyecdysone 5289-74-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000
Release date: 2023-08-11

ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD

Product: Hydroxyecdysone 5289-74-7
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5ton/month
Release date: 2023-08-21

5289-74-7, HydroxyecdysoneRelated Search:

β-Ecdysone[20-Hydroxyecdysone] 4'-Hydroxyacetophenone Dehydroepiandrosterone 2'-Hydroxyacetophenone 1-Decen-3-ol 3,7-DIMETHYL-1-OCTEN-3-OL 4-Methyl-3-decen-5-ol 2-Methyl-3-buten-2-ol turkesterone 1-N-PROPYLCYCLOPENTANOL 5-METHYL-2-HEPTEN-4-ONE 2-METHYL-1-PENTEN-3-OL TRANS-2-METHYLCYCLOPENTANOL (S)-1,2-DECANEDIOL 4-METHYL-4-HEPTEN-3-OL (S)-1,2-OCTANEDIOL Ponesterone A Hydroxyecdysone Ecdysterone

BETA-ECDYSONE

BETA-ECDYSONE,2,3,14,20,22,25-HEXAHYDROXY-7-CHOLESTEN-6-ONE

BETA-ECDYSTERONE

7,(5B)-CHOLESTEN-2BETA, 3BETA, 14ALPHA, 20BETA, 22R, 25-HEXOL-6-ONE

2B,3B,14A,20,22[R],25-HEXAHYDROXY-7-CHOLESTEN-6-ONE

2b,3b,14a,20b,22,25-hexahydroxycholest-7-en-6-one

2BETA,3BETA,14ALPHA,20BETA,22,25-HEXAHYDROXY-7-CHOLESTEN-6-ONE

(2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-TRIHYDROXY-10,13-DIMETHYL-17-((1R,2R)-1,2,5-TRIHYDROXY-1,5-DIMETHYL-HEXYL)-1,2,3,4,5,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-6-ONE

20-HYDROXYECDYSON

20-HYDROXYECDYSONE

POLYPODINE A

2,3,14,20,22,25-hexahydroxy-,(2-beta,3-beta,5-beta,22r)-cholest-7-en-6-on

2-beta,3-beta,14,20,22,25-hexahydroxy-5-beta-cholet-7-en-6-one

3-beta,14,20,22,25-hexahydroxy-2-bet(22r)-5-beta-cholest-7-en-6-on

commisterone

crustecdyson

SS-ECDYSONE,2,3,14,20,22,25-HEXAHYDROXY-7-CHOLESTEN-6-ONE

20-HYDROXYECDYSONE (B-ECDYSTERONE)

β-Ecdysone, Ecdysterone, Insect moulting hormone, Polypodine A, 2β,3β,14α,20β,22,25-Hexahydroxy-7-cholesten-6-one

Beta Ecdysterone 95% UV, with 70% 20-hydroxyecdysterone

Cholest-7-en-6-one, 2,3,14,20,22,25-hexahydroxy-, (2b,3b,5b,22R)-

Polypodin A

Viticosterone

20-beta-ecdysterone

2β,3β,14α,20β,22,25-Hexahydroxy-7-cholesten-6-one

β-Ecdysone, Ecdysterone, Insect moulting hormone

ECDYSONE, BETA-(RG)(PLEASE CALL)

Edysterone

Ecdysten

20-Hydroxyecdysone, 98%, from Arachnoides C. B. Clarke

20-Hydroxyecdysone,β-Ecdysone, 2β,3β,14α,20β,22,25-Hexahydroxy-7-cholesten-6-one, Ecdysterone, Insect moulting hormone, Polypodine A

ECDYSONE, B-(P)

20-Hydroxyedysone

(2β,3β,5β,22R)-2,3,14,20,22,25-Hexahydroxycholest-7-en-6-one

(2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-diMethyl-17-((2R,3R)-2,3,6-trihydroxy-6-Methylheptan-2-yl)-2,3,4,5,9,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6(10H)-one

20-Hydroxyecdysone, froM Arachnoides C. B. Clarke

B-ecdysone,Commisterone

(2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-((2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl)-1,2,3,4,5,10,11,12,13,15,16,17-dodecahydro-9H-cyclopenta[a]phenanthren-6(14H)-one

2β,3β,14α,20β,22,25-Hexahydroxycholest-7-en-6-one

20-Hydroxyecdysone, >=95%

hydroxyecdysone

HYDROXYECDYSONE, 20-

INSECT MOULTING HORMONE

ECDYSONE, BETA-

ECDYSTERONE

B-ECDYSONE

BETA-ECDYSON

Hydroxyecdysterone

professional manufacturer Ecdysterone 5289-74-7

Cyanotis Arachnoidea Extract (Ecdysone、Beta-ecdysterone)

crustecdysone

ecdysteron

isoinokosterone

the-7

BETA-ECDYSONE, 99% HPLC

BETA-ECDYSONE, 90% UV

BETA-ECDYSONE, 95+%

β-ECDYSONE,2,3,14,20,22,25-HEXAHYDROXY-7-CHOLESTEN-6-ONE