1H-PYRAZOLO[4,3-B]PYRIDINE
- Product Name
- 1H-PYRAZOLO[4,3-B]PYRIDINE
- CAS No.
- 272-52-6
- Chemical Name
- 1H-PYRAZOLO[4,3-B]PYRIDINE
- Synonyms
- PYRAZOLOPYRIDINE;4-Aza-1H-indazole;Pyrazolo[4,3-b]pyridine;1H-PYRAZOLO[4,3-B]PYRIDINE;7aH-pyrazolo[4,3-b]pyridine;1H-pyrazolo[4,3-b]pyridin...;1H-Pyrazolo[4,3-b]pyridine
- CBNumber
- CB1694536
- Molecular Formula
- C6H5N3
- Formula Weight
- 119.12
- MOL File
- 272-52-6.mol
1H-PYRAZOLO[4,3-B]PYRIDINE Property
- Boiling point:
- 294.5±13.0 °C(Predicted)
- Density
- 1.348±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- form
- Solid
- pka
- 10.94±0.30(Predicted)
- Appearance
- Off-white to light yellow Solid
- InChI
- InChI=1S/C6H5N3/c1-2-5-6(7-3-1)4-8-9-5/h1-4H,(H,8,9)
- InChIKey
- AMFYRKOUWBAGHV-UHFFFAOYSA-N
- SMILES
- C12C=NNC1=CC=CN=2
- CAS DataBase Reference
- 272-52-6(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- BLN00003
- Product name
- 1H-Pyrazolo[4,3-b]pyridine
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $320
- Updated
- 2024/03/01
- Product number
- W5033
- Product name
- 1H-Pyrazolo[4,3-b]pyridine
- Packaging
- 5g
- Price
- $252
- Updated
- 2021/12/16
- Product number
- 068760
- Product name
- 1H-Pyrazolo[4,3-b]pyridine
- Purity
- >95%
- Packaging
- 1g
- Price
- $416
- Updated
- 2021/12/16
- Product number
- OR30695
- Product name
- 1H-Pyrazolo[4,3-b]pyridine
- Packaging
- 250mg
- Price
- $54
- Updated
- 2021/12/16
- Product number
- 3H32-1-G2
- Product name
- 1H-Pyrazolo[4,3-b]pyridine
- Packaging
- 250mg
- Price
- $60
- Updated
- 2021/12/16
1H-PYRAZOLO[4,3-B]PYRIDINE Chemical Properties,Usage,Production
Synthesis
52090-62-7
272-52-6
1-(1H-pyrazolo[4,3-b]pyridin-1-yl)ethanone (973 mg, 6.04 mmol) was used as a raw material, which was dissolved in a solvent mixture of THF/MeOH (1:1, 16 mL). 10% NaOH aqueous solution (1.8 mL) was added. The reaction mixture was stirred at room temperature for 30 min, followed by neutralization of the reaction solution with 1.0 M HCl, dilution with water and extraction with EtOAc (2×). The organic phases were combined, washed with brine, dried over MgSO4 and concentrated to give 687 mg (96% yield) of 1H-pyrazolo[4,3-b]pyridine as a light yellow solid.1H NMR (DMSO-d6, 300 MHz) δ (ppm): 13.29 (br.s, 1H), 8.50 (d, J = 4.5 Hz, 1H), 8.27 (s , 1H), 8.00 (d, J = 8.7 Hz, 1H), 7.34 (dd, J = 8.7, 4.5 Hz, 1H).
References
[1] Patent: WO2013/30138, 2013, A1. Location in patent: Page/Page column 253
[2] Patent: EP1510516, 2005, A1. Location in patent: Page/Page column 135
1H-PYRAZOLO[4,3-B]PYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1H-PYRAZOLO[4,3-B]PYRIDINE manufacturers
- Product
- 1H-PYRAZOLO[4,3-B]PYRIDINE 272-52-6
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 97.5%
- Supply Ability
- 100 tons
- Release date
- 2022-02-22
- Product
- 1H-PYRAZOLO[4,3-B]PYRIDINE 272-52-6
- Price
- US $8.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10tons
- Release date
- 2018-12-24