ChemicalBook > CAS DataBase List > DL-THREO-BETA-HYDROXYASPARTIC ACID

DL-THREO-BETA-HYDROXYASPARTIC ACID

Product Name
DL-THREO-BETA-HYDROXYASPARTIC ACID
CAS No.
4294-45-5
Chemical Name
DL-THREO-BETA-HYDROXYASPARTIC ACID
Synonyms
THA;DL-THYA;NSC-119128;3-HYDROXY-D-ASPARTIC ACID;DL-threo-β-Hydroxyaspartate;D,L-threo-β-HydroxyAsparticAcid;threo-3-hydroxy-DL-aspartic acid;D,L-THREO-B-HYDROXYASPARTIC ACID;threo-3-Hydroxy-DL-asparatic acid;5β-Pregnane-3α,21-diol-11,20-dione
CBNumber
CB1697638
Molecular Formula
C4H7NO5
Formula Weight
149.1
MOL File
4294-45-5.mol
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DL-THREO-BETA-HYDROXYASPARTIC ACID Property

Melting point:
>230°C dec
Boiling point:
368.7±42.0 °C(Predicted)
Density 
1.738±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Aqueous Base (Slightly)
pka
2.13±0.27(Predicted)
form 
Solid
color 
White to Pale Beige
Stability:
Hygroscopic
InChIKey
YYLQUHNPNCGKJQ-JCYAYHJZSA-N
CAS DataBase Reference
4294-45-5
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H2775
Product name
DL-threo-β-Hydroxyaspartic acid
Packaging
50mg
Price
$174
Updated
2024/03/01
Sigma-Aldrich
Product number
H2775
Product name
DL-threo-β-Hydroxyaspartic acid
Packaging
250mg
Price
$370.8
Updated
2024/03/01
Usbiological
Product number
290162
Product name
D,L-threo-b-hydroxy aspartic acid
Packaging
50mg
Price
$386
Updated
2021/12/16
Usbiological
Product number
H9035-98
Product name
D,L-threo-b-Hydroxyaspartic Acid
Packaging
250mg
Price
$418
Updated
2021/12/16
TRC
Product number
H828525
Product name
DL-threo-β-Hydroxyaspartic acid
Packaging
100mg
Price
$180
Updated
2021/12/16
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DL-THREO-BETA-HYDROXYASPARTIC ACID Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

A glutamate uptake inhibitor

Uses

L-aspartate beta-carboxylase inhibitor, neurotoxic

Uses

DL-threo-β-Hydroxyaspartic acid (THA) has been used to block glutamate transport in cannulated sprague dawley rat.

Definition

ChEBI: (3S)-3-hydroxy-L-aspartic acid is the (3S)-diastereomer of 3-hydroxy-L-aspartic acid. It has a role as a metabolite. It is a conjugate acid of a (3S)-3-hydroxy-L-aspartate(2-) and a (3S)-3-hydroxy-L-aspartate(1-). It is an enantiomer of a (3R)-3-hydroxy-D-aspartic acid.

General Description

DL-threo-β-hydroxyaspartic acid (THA) is a glutamate uptake inhibitor.

DL-THREO-BETA-HYDROXYASPARTIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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DL-THREO-BETA-HYDROXYASPARTIC ACID Suppliers

3B Scientific (Wuhan) Corporation Limited
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0086-27-88063677 18186135292
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027-88063656
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sales@3bsc.com
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China
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J & K SCIENTIFIC LTD.
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86-10-82849933
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jkinfo@jkchemical.com
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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021-61259108 18621169109
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86-21-61259102
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China
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3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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86-21-50328109
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3bsc@sina.com
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China
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Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
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China
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Chemsky(shanghai)International Co.,Ltd.
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Beijing HuaMeiHuLiBiological Chemical
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Guangzhou Isun Pharmaceutical Co., Ltd
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Shanghai TaoSu Biochemical Technology Co., Ltd.
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Sigma-Aldrich
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021-61415566 800-8193336
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orderCN@merckgroup.com
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4294-45-5, DL-THREO-BETA-HYDROXYASPARTIC ACIDRelated Search:


  • DL-threo-β-Hydroxyaspartate
  • rac-(2S*,3S*)-2-Amino-3-hydroxybutanedioic acid
  • threo-3-Hydroxy-DL-asparatic acid
  • 5β-Pregnane-3α,21-diol-11,20-dione
  • D,L-THREO-B-HYDROXYASPARTIC ACID
  • DL-THREO-BETA-HYDROXYASPARTIC ACID
  • DL-THYA
  • THA
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  • threo-3-hydroxy-DL-aspartic acid
  • (2S,3S)-2-amino-3-hydroxy-succinic acid
  • DL-tHya, threo-2-Amino-3-hydroxysuccinic Acid
  • 3-HYDROXY-D-ASPARTIC ACID
  • D-Aspartic acid, 3-hydroxy-, (3R)-rel-
  • D,L-threo-β-HydroxyAsparticAcid
  • rel-(2S,3S)-2-Amino-3-hydroxysuccinic acid
  • NSC-119128
  • 4294-45-5
  • Amino Acids & Derivatives
  • Inhibitors
  • Neurochemicals