Chymotrypsin Substrate II, Fluorogenic

Product Name: Chymotrypsin Substrate II, Fluorogenic
CAS No.: 88467-45-2
Chemical Name: Chymotrypsin Substrate II, Fluorogenic
Synonyms: SUC-AAPF-AMC;FACTOR XIIA SUBSTRATE;Z-LYS-PHE-ARG-PNA 2HCL;SUC-ALA-ALA-PRO-PHE-MCA;SUC-ALA-ALA-PRO-PHE-AMC;Z-LYS-PHE-ARG-PNA DIHYDROCHLORIDE;Suc-Ala-Ala-Pro-Phe-AMC≥ 99% (HPLC);FACTOR XIIA SUBSTRATE DIHYDROCHLORIDE;CHYMOTRYPSIN SUBSTRATE II, FLUOROGENIC;5:PN:WO0197794 SEQID:34 claimed protein
CBNumber: CB1701335
Molecular Formula: C34H39N5O9
Formula Weight: 661.7
MOL File: 88467-45-2.mol

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Chymotrypsin Substrate II, Fluorogenic Property

Boiling point:: 1093.0±65.0 °C(Predicted)
Density: 1.347±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: Clear, colorless solution (10 mg/mL in Methanol)
form: White lyophilized solid
pka: 4.69±0.10(Predicted)
color: White to off-white

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S9761
Product name: N-Succinyl-Ala-Ala-Pro-Phe-7-amido-4-methylcoumarin
Purity: Leucine aminopeptidase substrate
Packaging: 1mg
Price: $94
Updated: 2024/03/01

Sigma-Aldrich

Product number: 230914
Product name: Chymotrypsin Substrate II, Fluorogenic
Packaging: 25mg
Price: $142
Updated: 2024/03/01

Sigma-Aldrich

Product number: S9761
Product name: N-Succinyl-Ala-Ala-Pro-Phe-7-amido-4-methylcoumarin
Purity: Leucine aminopeptidase substrate
Packaging: 5mg
Price: $315
Updated: 2024/03/01

TRC

Product number: C432958
Product name: Chymotrypsin Substrate II, Fluorogenic
Packaging: 50mg
Price: $255
Updated: 2021/12/16

Chem-Impex

Product number: 04643
Product name: Suc-Ala-Ala-Pro-Phe-AMC,99%(HPLC)
Purity: 99%(HPLC)
Packaging: 50MG
Price: $436.8
Updated: 2021/12/16

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Chymotrypsin Substrate II, Fluorogenic Chemical Properties,Usage,Production

Description

Chymotrypsin Substrate II, Fluorogenic finds widespread utility across diverse scientific research applications, encompassing the exploration of protein-protein interactions, enzyme kinetics, and receptor binding. Notably, its cost-effectiveness and user-friendly nature render it an appealing choice for researchers. Additionally, this peptide has been instrumental in delving into the intricate world of cell signaling pathways and unraveling the mechanisms governing gene expression regulation. It is postulated to function as a substrate for enzymes while also engaging with receptors. The prevailing belief suggests that the peptide effectively binds to specific receptors, subsequently triggering their activation and instigating consequential alterations in cellular signaling pathways.

Chemical Properties

White powder

Uses

Chymotrypsin Substrate II, Fluorogenic (cas# 88467-45-2) is a useful compound in organic synthesis and acts as a substrate for chymotrypsin enzyme.

Biological Activity

Sensitive fluorogenic substrate for the quantitative determination of chymotrypsin activity (excitation maximum: ~380 nm; emission maximum: ~460 nm).

References

[1] G B IRVINE C H W M Ennis. Visual detection of peptidase activity using fluorogenic substrates in a microtiter plate assay.[J]. Analytical biochemistry, 1990, 185 2: 304-307. DOI:10.1016/0003-2697(90)90298-n.
[2] LASZLO GRAF. Selective alteration of substrate specificity by replacement of aspartic acid-189 with lysine in the binding pocket of trypsin[J]. Biochemistry Biochemistry, 1987, 26 9: 2616-2623. DOI:10.1021/bi00383a031.
[3] OSHIMA G. Interaction of alpha-chymotrypsin with dimyristoyl phosphatidylcholine vesicles.[J]. Journal of biochemistry, 1984, 95 4: 1131-1136. DOI:10.1093/oxfordjournals.jbchem.a134701.
[4] OSHIMA G. Stimulation by phospholipid vesicles of proteolysis of egg white lysozyme by chymotrypsin.[J]. Journal of biochemistry, 1983, 5 1: 1615-1620. DOI:10.1093/OXFORDJOURNALS.JBCHEM.A134509.

Chymotrypsin Substrate II, Fluorogenic Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Chymotrypsin Substrate II, Fluorogenic manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: FACTOR XIIA SUBSTRATE DIHYDROCHLORIDE 88467-45-2
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-11

88467-45-2, Chymotrypsin Substrate II, FluorogenicRelated Search:

SUC-ALA-GLU-PRO-PHE-AMC SUC-ALA-LEU-PRO-PHE-AMC succinimidyl-alanyl-phenylalanyl-prolyl-phenylalanine 4-nitroanilide SUC-ALA-ALA-PRO-LYS-PNA SUC-ALA-ALA-PRO-ASP-PNA SUC-ALA-ILE-PRO-PHE-PNA SUC-GLY-PHE-GLY-PNA CHYMOTRYPSIN SUBSTRATE I, COLORIMETRIC SUC-ALA-ALA-PRO-VAL-AMC SUC-ALA-PRO-PNA SUC-ALA-PHE-LYS-AMC SUC-PHE-PRO-PHE-PNA SUC-ALA-VAL-PRO-PHE-PNA SUC-ALA-GLU-PRO-PHE-PNA Suc-Phe-Gly-Leu-βNA SUC-PHE-ALA-ALA-PHE-PNA SUC-ALA-ALA-VAL-AMC SUC-ALA-ALA-PRO-NVA-PNA

SUCCINYL-L-ALANYL-L-ALANYL-L-PROLYL-L-PHENYLALANINE 4-METHYLCOUMARYL-7-AMIDE

SUC-AAPF-AMC

SUC-ALA-ALA-PRO-PHE-MCA

SUC-ALA-ALA-PRO-PHE-7-AMINO-4-METHYLCOUMARIN

SUC-ALA-ALA-PRO-PHE-AMC

N-SUCCINYL-ALA-ALA-PRO-PHE 7-AMIDO-4-METHYLCOUMARIN

Z-LYS-PHE-ARG-PNA 2HCL

Chymotrypsin Substrate II, Fluorogenic - CAS 88467-45-2 - Calbiochem

CHYMOTRYPSIN SUBSTRATE II, FLUOROGENIC

FACTOR XIIA SUBSTRATE DIHYDROCHLORIDE

N-SUCCINYL-ALA-ALA-PRO-PHE 7-AMIDO-4-*ME THYLCOUMARI

FACTOR XIIA SUBSTRATE

succinylalanylalanyl-prolyl-phenylalanine-4-methylcoumaryl-7-amide

Z-LYS-PHE-ARG-PNA DIHYDROCHLORIDE

Suc-Ala-Ala-Pro-Phe-AMC≥ 99% (HPLC)

L-Phenylalaninamide, N-(3-carboxy-1-oxopropyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-

5:PN:WO0197794 SEQID:34 claimed protein

4-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-2-[(4-methyl-2-oxochromen-7-yl)amino]-3-phenylpropanoyl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoic acid

N-(3-Carboxy-1-oxopropyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-Phenylalaninamide

88467-45-2

C34H39N5O9

Enzymes, Inhibitors, and Substrates

Enzyme Substrates

Leucine Aminopeptidase

Substrates by Enzyme

BioChemical

Biochemicals and Reagents

Chymotrypsin, alphaEnzyme Substrates

Leucine aminopeptidase

Leucine AminopeptidaseEnzyme Substrates

Enzyme Substrates

Protease Substrates

Substrates by Enzyme