3-PHENYLPROPIONITRILE

ChemicalBook > CAS DataBase List > 3-PHENYLPROPIONITRILE

3-PHENYLPROPIONITRILE

Product Name: 3-PHENYLPROPIONITRILE
CAS No.: 645-59-0
Chemical Name: 3-PHENYLPROPIONITRILE
Synonyms: NSC 16936;phenethylcyanide;Phenethyl cyanide;Benzylacetonitrile;Phenylpropionitrile;HYDROCINNAMONITRILE;Benzenepropionitrile;2-Phenylethylcyanide;benzenepropanenitrile;(2-Cyanoethyl)benzene
CBNumber: CB1733015
Molecular Formula: C9H9N
Formula Weight: 131.17
MOL File: 645-59-0.mol

Less

3-PHENYLPROPIONITRILE Property

Melting point:: −2-−1 °C(lit.)
Boiling point:: 113 °C9 mm Hg(lit.)
Density: 1.001 g/mL at 25 °C(lit.)
refractive index: n20/D 1.521(lit.)
Flash point:: >230 °F
storage temp.: Sealed in dry,Room Temperature
solubility: 1.68g/l (calculated)
form: Liquid
Specific Gravity: 1
color: Clear colorless to light yellow
Odor: powerful nasturtium
BRN: 636348
Exposure limits: NIOSH: IDLH 25 mg/m3
CAS DataBase Reference: 645-59-0(CAS DataBase Reference)
EPA Substance Registry System: Benzenepropanenitrile (645-59-0)

Less

Safety

Hazard Codes: T,C
Risk Statements: 23/24/25-36-34
Safety Statements: 36/37/39-45-27-26
RIDADR: UN 3276 6.1/PG 3
WGK Germany: 3
RTECS: MW5604750
TSCA: Yes
HazardClass: 6.1
PackingGroup: II
HS Code: 29269095

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 171573
Product name: 3-Phenylpropionitrile
Purity: 99%
Packaging: 10g
Price: $182
Updated: 2024/03/01

TCI Chemical

Product number: P0611
Product name: 3-Phenylpropionitrile
Purity: >98.0%(GC)
Packaging: 25g
Price: $76
Updated: 2024/03/01

Alfa Aesar

Product number: L06483
Product name: 3-Phenylpropionitrile, 98%
Packaging: 10g
Price: $44.65
Updated: 2024/03/01

Alfa Aesar

Product number: L06483
Product name: 3-Phenylpropionitrile, 98%
Packaging: 50g
Price: $147.65
Updated: 2024/03/01

TRC

Product number: P336205
Product name: 3-Phenylpropionitrile
Packaging: 1g
Price: $120
Updated: 2021/12/16

Less

3-PHENYLPROPIONITRILE Chemical Properties,Usage,Production

Chemical Properties

clear colorless to light yellow liquid

Uses

3-Phenylpropionitrile was used to study the free enzyme activity of nitrilase AtNIT1.

Uses

A glucosinolate enzymic hydrolosis product with potential antibacterial activities against plant pathogenic bacteria. 3-Phenylpropionitrile is occasionally used in perfume compositions, mainly as a minor ingredient in artificial flower absolutes, etc. The material can also be used in certain types of exotic or very heavy floral fragrance, e. g. Stephanotis, Pikake, Keora, Ginger Lily, Tiare, Coffee flower, etc. Its warm and piquant, vegetable pungency is utilized in flavor compositions for seasonings, etc. and in various spice blends. Normal use concentration is equivalent to about 1 to 3 ppm in the finished product.

Definition

ChEBI: A nitrile that is propionitrile in which one of the methyl hydrogens has been replaced by a phenyl group.

Preparation

To a stirred solution of 3-phenylpropanamide (50 mg, 0.34 mmol) in acetonitrile (0.8 mL) at room temperature were successively added formic acid (0.2 mL) and paraformaldehyde (50 mg, 1.67 mmol). The reaction mixture was then refluxed for 12 h, and the solution obtained was cooled to room temperature.
Work-up A: The crude mixture was concentrated under reduced pressure, and the residue was subjected to flash chromatography on silica gel (230–240 mesh) eluting with hexane/ethyl acetate (7:3) to yield 3-phenylpropanonitrile (37 mg, 85%).
Work-up B: The reaction mixture was diluted with ethyl acetate (10 mL) and washed successively with saturated sodium hydrogen carbonate solution (5 mL) and water (5 mL). The combined aqueous layers were extracted with ethyl acetate (2 × 10 mL). The combined organic layers were dried over Na2SO4, filtered, and concentrated. The crude 3-phenylpropanonitrile was purified as described above (Work-up A).

Synthesis Reference(s)

Journal of the American Chemical Society, 98, p. 4685, 1976 DOI: 10.1021/ja00431a078
Chemical and Pharmaceutical Bulletin, 10, p. 427, 1962 DOI: 10.1248/cpb.10.427

General Description

The effect of 3-Phenylpropionitrile on the growth and survival of woodlouse Porcellio scaber has been studied.

3-PHENYLPROPIONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

3-PHENYLPROPIONITRILE Suppliers

Americas 1 Belgium 2 Canada 2 China 62 Europe 1 Germany 6 India 8 Japan 5 Singapore 1 Switzerland 1 Ukraine 1 United Kingdom 7 United States 20 USA 1 Global 118

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14103
Advantage: 59

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 19185
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
Advantage: 64

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15402
Advantage: 60

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Maya High Purity Chemicals

Tel: +86 (573) 82222445 (0)18006601000 452520369
Fax: +86 (573) 82222643
Email: sales@maya-r.com
Country: China
ProdList: 11707
Advantage: 57

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

Beijing innoChem Science & Technology Co.,Ltd.

Tel: 400-810-7969 010-59572699
Fax: 010-59572688
Email: ningzi.li@inno-chem.com.cn
Country: China
ProdList: 6134
Advantage: 55

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66099280 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19915
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41457
Advantage: 60

Shanghai Xingui Biotechnology Co., Ltd.

Tel: 17501653713
Email: xingui2022@126.com
Country: China
ProdList: 9997
Advantage: 58

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 16166
Advantage: 55

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

parabiochem

Tel: 025-83453382-8005
Fax: 025-83453382
Email: sale@parabiochem.com
Country: China
ProdList: 9595
Advantage: 55

Shandong Xiya Chemical Co., Ltd.

Tel: 4009903999 13395398332
Fax: 0539-6365991
Email: sales@xiyashiji.com
Country: China
ProdList: 20806
Advantage: 60

Guangdong wengjiang Chemical Reagent Co., Ltd.

Tel: 0751-2886750 13927877953
Fax: 0751-2886750
Email: 3005811397@qq.com
Country: China
ProdList: 13320
Advantage: 58

Guangzhou Jhd Chemical Reagent Co., Ltd.

Tel: 020-84383047
Fax: 020-84380294
Email: sales@jhd.com.cn
Country: China
ProdList: 9186
Advantage: 65

JinJin Le Chemical Co., Ltd

Tel: 10106090
Email: jjlchem2@163.com
Country: China
ProdList: 9981
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718 +86-13336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29730
Advantage: 60

Rhawn Reagent

Tel: 400-400-1332688 18019345275
Fax: 400-133-2688
Email: amy@rhawn.cn
Country: China
ProdList: 15497
Advantage: 58

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400-6387771-6039 18920564737
Email: sales@heowns.com
Country: China
ProdList: 23388
Advantage: 60

Chengdu Forest Science and Technology Development Co,. Ltd

Tel: 028-87925786 18010564218
Fax: 028-61777050
Email: vendi@cdforestchem.com
Country: China
ProdList: 1992
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418671 +8618949823763
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34563
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: 571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52849
Advantage: 58

Hubei Jusheng Technology Co.,Ltd.

Tel: 18871490254
Fax: 027-59599243
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 28172
Advantage: 58

Nanjing jinheyou Trading Co., Ltd.

Tel: 15705188088
Email: admin@jheyou.com
Country: CHINA
ProdList: 1268
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49732
Advantage: 58

Hubei huizepu Pharmaceutical Technology Co., Ltd

Tel: 027-0185-0185-07139096-265 19371278702
Fax: QQ:1925957016
Email: 18507139096@163.com
Country: China
ProdList: 3006
Advantage: 58

Nanjing shengyilai Chemical Co., Ltd

Tel: 19951936396
Email: 3158688292@qq.com
Country: China
ProdList: 4856
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: 029-81024372 15029046529
Fax: 029-88380327
Email: 1027@dideu.com
Country: China
ProdList: 10005
Advantage: 58

Henan Weitesi Chemical Technology Co. LTD

Tel: 0371-0371-55135753 18003832934
Fax: QQ：2853979818
Email: 2853979818@qq.com
Country: China
ProdList: 9984
Advantage: 58

Huaian Jiamu Biotechnology Co., Ltd.

Tel: 0517-83187139 18205232085
Email: cai@jiamu-bio.com
Country: China
ProdList: 2926
Advantage: 58

Hebei Zhenjia new material Co., LTD

Tel: 0319-5925599 13315915972
Email: 13313090628@163.com
Country: China
ProdList: 2916
Advantage: 58

Rhawn Reagent

Tel: 400-1332688 18019345275
Fax: 400-133-2688
Email: amy@rhawn.cn
Country: China
ProdList: 1438
Advantage: 58

Suzhou Daolan Biomedical Technology Co., Ltd.

Tel: 15952404857
Email: sales@dolanpharm.com
Country: China
ProdList: 1980
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39665
Advantage: 58

Shanghai Yingxin laboratory equipment Co., Ltd

Tel: 021-021-59178156 15300768757
Email: 359382369@qq.com
Country: China
ProdList: 10674
Advantage: 58

Shanghai Haohong Scientific Co., Ltd.

Tel: 400-400-8210725 17717813675;
Email: malulu@leyan.com
Country: China
ProdList: 39988
Advantage: 58

Shanghai Guchen Biotechnology Co., LTD

Tel: 021-34675735 19147740836
Email: 1986399151@qq.com
Country: China
ProdList: 9844
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50464
Advantage: 58

Shanghai Aladdin Biochemical Technology Co.,Ltd.

Tel: 400-6206333 1316706386
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 48459
Advantage: 58

Chengdu Peter-like Biotechnology Co., Ltd.

Tel: 028-81700200 13308200041
Email: 2851167782@qq.com
Country: China
ProdList: 11183
Advantage: 58

XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.

Tel: +8618950047208
Email: ellena@amitychem.com
Country: China
ProdList: 43416
Advantage: 58

Less

View Lastest Price from 3-PHENYLPROPIONITRILE manufacturers

Nanjing jinheyou Trading Co., Ltd.

Product: 3-PHENYLPROPIONITRILE 645-59-0
Price: US $0.00/g
Min. Order: 1g
Purity: 95%min
Supply Ability: 20kg/month
Release date: 2019-11-19

645-59-0, 3-PHENYLPROPIONITRILERelated Search:

Benzoylacetonitrile 1-Benzocyclobutenecarbonitrile 3-CYANOCHROMONE METHYL 4-(CYANOACETYL)BENZOATE 4-CHLOROBENZOYLACETONITRILE 3-PHENYLPROPIONITRILE 3-CHLOROBENZOYLACETONITRILE 4-(TRIFLUOROMETHOXY)BENZOYL ACETONITRILE 3-(TRIFLUOROMETHYL)BENZOYLACETONITRILE 3-(2-CHLOROPHENYL)PROPIONITRILE 2-CHLOROBENZOYLACETONITRILE 3-(4-HYDROXYPHENYL)PROPIONITRILE 4-Methoxybenzoylacetonitrile PHENYLSUCCINONITRILE 2-alpha-Phenylpropionitrile,2-PHENYLPROPIONITRILE 3-PHENYLPROPIONITRILE 2,3-diphenylpropiononitrile ethyl 2-cyano-3-phenyl-propanoate

(2-Cyanoethyl)benzene

3-Phenylpropanenitrile

3-Phenylpropiononitrile

HydrocinnaMonitrile, 99+% 10GR

1-Cyano-2-phenylethane

1-Phenyl-2-cyanoethane

3-Phenylpropanonitrile

DihydrocinnaMonitrile

NSC 16936

3-Phenylpropionitrile 99%

benzenepropanenitrile

Benzenepropionitrile

beta-Phenylethyl cyanide

Hydrocinnamique nitrile

hydrocinnamiquenitrile

Phenethyl cyanide

phenethylcyanide

Phenylpropionitrile

HYDROCINNAMONITRILE

BETA-PHENYL PROPIONITRILE

B-PHENYLETHYL CYANIDE

2-Phenylethylcyanide

3-PHENYLPROPIONITRILE

Hydrocinnamonitrile, 99+%

Benzenepropiononitrile

Benzylacetonitrile

3-Phenylpropionitrile,98%

3-Phenylpropionitrile&gt

Benzenepropanenitrile (9CI, ACI)

645-59-0

C6H5CH22CN

C9H9N1

C6H5CH2CH2CN

Building Blocks

C8 to C9

Cyanides/Nitriles

Nitrogen Compounds

Organic Building Blocks

Intermediates & Fine Chemicals

Pharmaceuticals

Aromatics