3-NITROPHENETHYL ALCOHOL
- Product Name
- 3-NITROPHENETHYL ALCOHOL
- CAS No.
- 52022-77-2
- Chemical Name
- 3-NITROPHENETHYL ALCOHOL
- Synonyms
- Einecs 257-611-2;2-(3-Nitrophenyl);TIMTEC-BB SBB008558;3-Nitrobenzeneethanol;3-nitro-benzeneethano;2-(3-Nitrophnyl)ethanol;3-NITROPHENETHYL ALCOHOL;2-(3-Nitrophenyl)ethanol;m-nitrophenethyl alcohol;Benzeneethanol, 3-nitro-
- CBNumber
- CB1736157
- Molecular Formula
- C8H9NO3
- Formula Weight
- 167.16
- MOL File
- 52022-77-2.mol
3-NITROPHENETHYL ALCOHOL Property
- Melting point:
- 47-50 °C (lit.)
- Boiling point:
- 141-146 °C/4 mmHg (lit.)
- Density
- 1.2917 (rough estimate)
- refractive index
- 1.5570 (estimate)
- Flash point:
- >230 °F
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 14.65±0.10(Predicted)
- form
- solid
- Appearance
- Light yellow to yellow Solid
- InChI
- InChI=1S/C8H9NO3/c10-5-4-7-2-1-3-8(6-7)9(11)12/h1-3,6,10H,4-5H2
- InChIKey
- PWZWTSYUZQZFKE-UHFFFAOYSA-N
- SMILES
- C1(CCO)=CC=CC([N+]([O-])=O)=C1
- EPA Substance Registry System
- Benzeneethanol, 3-nitro- (52022-77-2)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 281794
- Product name
- 3-Nitrophenethyl alcohol
- Purity
- 98%
- Packaging
- 1g
- Price
- $112
- Updated
- 2025/07/31
- Product number
- 281794
- Product name
- 3-Nitrophenethyl alcohol
- Purity
- 98%
- Packaging
- 5g
- Price
- $499
- Updated
- 2023/06/20
- Product number
- 153294
- Product name
- 3-Nitrophenethyl alcohol
- Purity
- 95%
- Packaging
- 5g
- Price
- $574
- Updated
- 2021/12/16
- Product number
- CHM0007243
- Product name
- 2-(3-NITROPHENYL) ETHANOL
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $702.06
- Updated
- 2021/12/16
- Product number
- 153294
- Product name
- 3-Nitrophenethyl alcohol
- Purity
- 95%
- Packaging
- 10g
- Price
- $1036
- Updated
- 2021/12/16
3-NITROPHENETHYL ALCOHOL Chemical Properties,Usage,Production
Uses
3-Nitrophenethyl alcohol has been employed as substrate to engineer nitrobenzene dioxygenase for the production of the highly potent antioxidant, hydroxytyrosol.
Synthesis
1877-73-2
52022-77-2
Under nitrogen protection, 200 mg of 3-nitrophenylacetic acid was dissolved in 2 mL of anhydrous tetrahydrofuran and 1 mL of borane-tetrahydrofuran solution (1 M) was added slowly and dropwise. The reaction mixture was stirred at room temperature for 12 h, during which the progress of the reaction was monitored by thin layer chromatography (TLC). Upon completion of the reaction, a small amount of water was carefully added dropwise to quench the reaction. Subsequently, the reaction system was adjusted to alkaline by adding excess saturated sodium bicarbonate solution. Extraction was carried out with ethyl acetate and the organic layer was separated, dried over anhydrous sodium sulfate and filtered. The filtrate was concentrated under reduced pressure to give the crude product. Finally, purification by column chromatography afforded 125 mg of 3-nitrophenylethanol (Intermediate XVI) in 68% yield.
References
[1] Patent: CN103787992, 2016, B. Location in patent: Paragraph 0309-0312
[2] Patent: WO2014/182829, 2014, A1. Location in patent: Page/Page column 55
[3] Patent: WO2016/191172, 2016, A1. Location in patent: Page/Page column 78
[4] Helvetica Chimica Acta, 1973, vol. 56, p. 2460 - 2479
[5] Journal of the American Chemical Society, 1982, vol. 104, # 7, p. 1937 - 1951
3-NITROPHENETHYL ALCOHOL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-NITROPHENETHYL ALCOHOL manufacturers
- Product
- 3-NITROPHENETHYL ALCOHOL 52022-77-2
- Price
- US $6.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1kg, 5kg, 50kg
- Release date
- 2020-01-09