ETHYL 3,5-DIMETHYL-1H-4-PYRAZOLECARBOXYLATE
- Product Name
- ETHYL 3,5-DIMETHYL-1H-4-PYRAZOLECARBOXYLATE
- CAS No.
- 35691-93-1
- Chemical Name
- ETHYL 3,5-DIMETHYL-1H-4-PYRAZOLECARBOXYLATE
- Synonyms
- Ethyl 3,5-Dimethylpyrazole-4-carboxylate;3,5-dimethylpyrazole-4-ethyl carboxylate;Ethyl 3,5-dimethyl-1H-pyrazol-4-carboxylate;ETHYL 3,5-DIMETHYL-1H-4-PYRAZOLECARBOXYLATE;3,5-Dimethyl-4-(ethoxycarbonyl)-1H-pyrazole;ETHYL 3,5-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLATE;ETHYL 3,5-DIMETHYL-1H-PYRRAZOLE-4-CARBOXYLATE;3,5-dimethyl-4-pyrazolecarboxylicaciethylester;3,5-dimethylpyrazole-4-carboxylicacidethylester;Ethyl 3,5-dimethyl-1H-pyrazole-4-carboxylate
- CBNumber
- CB1737992
- Molecular Formula
- C8H12N2O2
- Formula Weight
- 168.19
- MOL File
- 35691-93-1.mol
ETHYL 3,5-DIMETHYL-1H-4-PYRAZOLECARBOXYLATE Property
- Melting point:
- 66 °C
- Boiling point:
- 284.8±35.0 °C(Predicted)
- Density
- 1.136±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- form
- solid
- pka
- 12.82±0.50(Predicted)
- Appearance
- White to off-white Solid
- CAS DataBase Reference
- 35691-93-1
Safety
- HazardClass
- IRRITANT
- HS Code
- 2933199090
- Toxicity
- LDLo oral in mouse: 250mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- E917423
- Product name
- Ethyl3,5-dimethyl-1h-4-pyrazolecarboxylate
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- OR9878
- Product name
- Ethyl 3,5-dimethyl-1H-pyrazole-4-carboxylate
- Packaging
- 1g
- Price
- $26
- Updated
- 2021/12/16
- Product number
- 4H23-1-V4
- Product name
- Ethyl 3,5-dimethyl-1H-pyrazole-4-carboxylate
- Packaging
- 1g
- Price
- $32
- Updated
- 2021/12/16
- Product number
- 042828
- Product name
- Ethyl 3,5-dimethyl-1H-pyrazole-4-carboxylate
- Purity
- >95%
- Packaging
- 1g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- 4H23-1-V4
- Product name
- Ethyl 3,5-dimethyl-1H-pyrazole-4-carboxylate
- Packaging
- 5G
- Price
- $128
- Updated
- 2021/12/16
ETHYL 3,5-DIMETHYL-1H-4-PYRAZOLECARBOXYLATE Chemical Properties,Usage,Production
Synthesis
603-69-0
35691-93-1
General procedure for the synthesis of ethyl 3,5-dimethyl-1H-4-pyrazolecarboxylate from ethyl bisacetoacetate: To a solution of ethyl bisacetoacetate (4.6 g, 26.7 mmol) in ethanol (50 mL) was added hydrazine hydrochloride (1.8 g, 26.7 mmol). The reaction mixture was heated to reflux and kept for 2 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. The resulting residue was washed with ethyl acetate to afford ethyl 3,5-dimethyl-1H-4-pyrazolecarboxylate as a colorless solid (3.1 g, 69% yield), which was pure enough to be used directly in the subsequent reaction.
References
[1] Patent: WO2014/49133, 2014, A1. Location in patent: Page/Page column 44
[2] Justus Liebigs Annalen der Chemie, 1894, vol. 279, p. 237
[3] Archiv der Pharmazie (Weinheim, Germany), 1926, p. 346
[4] Zeitschrift fur Physikalische Chemie, 2013, vol. 227, # 6-7, p. 841 - 856
[5] Journal of Organic Chemistry, 2018, vol. 83, # 12, p. 6454 - 6465
ETHYL 3,5-DIMETHYL-1H-4-PYRAZOLECARBOXYLATE Preparation Products And Raw materials
Raw materials
Preparation Products
ETHYL 3,5-DIMETHYL-1H-4-PYRAZOLECARBOXYLATE Suppliers
- Tel
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- Country
- Belgium
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View Lastest Price from ETHYL 3,5-DIMETHYL-1H-4-PYRAZOLECARBOXYLATE manufacturers
- Product
- ETHYL 3,5-DIMETHYL-1H-4-PYRAZOLECARBOXYLATE 35691-93-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-25