3,4-DIMETHOXYCHALCONE

Product Name: 3,4-DIMETHOXYCHALCONE
CAS No.: 5416-71-7
Chemical Name: 3,4-DIMETHOXYCHALCONE
Synonyms: AKOS 220-38;3,4-DIMETHOXYCHALCONE;DIMETHOXYCHALCONE,3,4-;LABOTEST-BB LT00454345;3,4-Dimethoxychalcone, 10 mM in DMSO;3,4 Dimethoxychalcone,3,4Dimethoxychalcone;3-(3,4-Dimethoxyphenyl)-1-phenyl-2-propen-1-one;3-(3,4-DIMETHOXYPHENYL)-1-PHENYLPROP-2-EN-1-ONE;2-Propen-1-one, 3-(3,4-dimethoxyphenyl)-1-phenyl-;(E)-3-(3,4-DIMETHOXYPHENYL)-1-PHENYLPROP-2-EN-1-ONE
CBNumber: CB1738924
Molecular Formula: C17H16O3
Formula Weight: 268.31
MOL File: 5416-71-7.mol

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3,4-DIMETHOXYCHALCONE Property

Melting point:: 88°C
Boiling point:: 421.8±45.0 °C(Predicted)
Density: 1.128±0.06 g/cm3(Predicted)
form: Solid
color: Light yellow to green yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S798126
Product name: 3,4-DIMETHOXYCHALCONE
Purity: Aldrich<sup>CPR</sup>
Packaging: 1 unit
Price: $152
Updated: 2026/03/19

Sigma-Aldrich

Product number: S798126
Product name: 3,4-DIMETHOXYCHALCONE
Purity: AldrichCPR
Packaging: 10MG
Price: $134
Updated: 2023/06/20

Adipogen Life Sciences

Product number: AG-CN2-0531-M010
Product name: 3,4-Dimethoxychalcone
Purity: ≥98%(HPLC)
Packaging: 10mg
Price: $30
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD137917
Product name: 3,4-Dimethoxychalcone
Packaging: 10g
Price: $42
Updated: 2021/12/16

Adipogen Life Sciences

Product number: AG-CN2-0531-M050
Product name: 3,4-Dimethoxychalcone
Purity: ≥98%(HPLC)
Packaging: 50mg
Price: $55
Updated: 2021/12/16

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3,4-DIMETHOXYCHALCONE Chemical Properties,Usage,Production

Uses

3,4-Dimethoxychalcone is a Caloric restriction mimetics (CRMs). 3,4-Dimethoxychalcone induces the deacetylation of cytoplasmic proteins and stimulates autophagy flux. 3,4-Dimethoxychalcone can be used for cardiac and cancer diseases research[1].

in vivo

3,4-Dimethoxychalcone (230 mg/kg for intraperitoneal injection) induces the nuclear translocation of TFEB and TFE3 of liver and heart tissues in Female C57/BL6 mice^[1].

References

[1] Okolo EN, et al. New chalcone derivatives as potential antimicrobial and antioxidant agent. Sci Rep. 2021 Nov 5;11(1):21781. DOI:10.1038/s41598-021-01292-5
[2] Chen G, et al. 3,4-Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB. EMBO Mol Med. 2019 Nov 7;11(11):e10469. DOI:10.15252/emmm.201910469

3,4-DIMETHOXYCHALCONE Preparation Products And Raw materials

Raw materials

Preparation Products

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3,4-DIMETHOXYCHALCONE Suppliers

China 39 Germany 2 India 3 United Kingdom 3 United States 4 Global 51

Meryer (Shanghai) Chemical Technology Co., Ltd.

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5416-71-7, 3,4-DIMETHOXYCHALCONERelated Search:

3,4-DIMETHOXYCHALCONE,DIMETHOXYCHALCONE,3,4- 2',4-DIHYDROXY-4',6'-DIMETHOXYCHALCONE 2'-HYDROXY-2,3-DIMETHOXYCHALCONE 4,4'-DIMETHOXYCHALCONE,DIMETHOXYCHALCONE,4,4'-,DIMETHOXYCHALCONE,4,4'-(RG),4,4'-Dimethoxychalcone,99% 2',6'-DIHYDROXY-4,4'-DIMETHOXYCHALCONE,DIHYDROXY-4,4'-DIMETHOXYCHALCONE, 2',6'- Pashanone DIMETHOXYCHALCONE,3,4-(RG),3,4'-DIMETHOXYCHALCONE 2''-HYDROXY-4,4''-DIMETHOXYCHALCONE 4'-CHLORO-2,5-DIMETHOXYCHALCONE 4'-CHLORO-3,4-DIMETHOXYCHALCONE 2'-HYDROXY-3,4-DIMETHOXYCHALCONE 2''-HYDROXY-5''-METHYL-2,4-DIMETHOXYCHALCONE 2'-HYDROXY-2,4'-DIMETHOXYCHALCONE 5-BROMO-2,2'-DIHYDROXY-4',6'-DIMETHOXYCHALCONE 4-CHLORO-3',4'-DIMETHOXYCHALCONE 2''-HYDROXY2.5''-DIMETHOXYCHALCONE 2,2'-DIHYDROXY-4',6'-DIMETHOXYCHALCONE (E)-2',6'-dihydroxy-4,4'-dimethoxychalcone

LABOTEST-BB LT00454345

DIMETHOXYCHALCONE,3,4-

(E)-3-(3,4-DIMETHOXYPHENYL)-1-PHENYLPROP-2-EN-1-ONE

AKOS 220-38

3,4-DIMETHOXYCHALCONE

3-(3,4-DIMETHOXYPHENYL)-1-PHENYLPROP-2-EN-1-ONE

2-Propen-1-one, 3-(3,4-dimethoxyphenyl)-1-phenyl-

3,4 Dimethoxychalcone,3,4Dimethoxychalcone

3-(3,4-Dimethoxyphenyl)-1-phenyl-2-propen-1-one

3,4-Dimethoxychalcone, 10 mM in DMSO

5416-71-7

Chalcones