4-ANDROSTEN-3,17-DIONE-2,2,4,6,6,16,16-D7

4-ANDROSTEN-3,17-DIONE-2,2,4,6,6,16,16-D7 Property

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Solid

color 

Pale Yellow to Light Orange

Appearance

off-white solid

InChI

InChI=1S/C19H26O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-16H,3-10H2,1-2H3/t14-,15-,16-,18-,19-/m0/s1/i3D2,6D2,7D2,11D

InChIKey

AEMFNILZOJDQLW-NBGHNZKBSA-N

SMILES

C[C@]12CC([2H])([2H])C(C([2H])=C1C([2H])([2H])C[C@@]1([H])[C@]3([H])CC([2H])([2H])C([C@]3(CC[C@@]12[H])C)=O)=O

CAS Number Unlabeled

63-05-8

Hazard and Precautionary Statements (GHS)

4-ANDROSTEN-3,17-DIONE-2,2,4,6,6,16,16-D7 Chemical Properties,Usage,Production

Description

Androstenedione is a steroid hormone produced in testes in the ovary and in the adrenal cortex. Androstenedione is a precursor of testosterone and estrone. Androstenedione originates either from the conversion of dehydroepiandrosterone or from 17-hydroxyprogesterone. Androstenedione (ASD) is a biomarker used in the diagnostic workup of hyperandrogenism, congenital adrenal hyperplasia, premature adrenarche, and polycystic ovary syndrome (PCOS).

Uses

Androst-4-ene-3,17-dione-2,2,4,6,6,16,16-d7 is an intermediate in the synthesis of Dehydroepiandrosterone-d5 which is the labeled analogue of Dehydro Epiandrosterone (D229585). Dehydro Epiandrosterone is a major secretory steroidal product of the adrenal gland