ChemicalBook > CAS DataBase List > ETHYL 3-METHYL-1,2,4-OXADIAZOLE-5-CARBOXYLATE

ETHYL 3-METHYL-1,2,4-OXADIAZOLE-5-CARBOXYLATE

Product Name
ETHYL 3-METHYL-1,2,4-OXADIAZOLE-5-CARBOXYLATE
CAS No.
40019-21-4
Chemical Name
ETHYL 3-METHYL-1,2,4-OXADIAZOLE-5-CARBOXYLATE
Synonyms
ethyl 3-​oxadiazole-​ethyl 3-oxadiazole-;ETHYL 3-METHYL-1,2,4-OXADIAZOLE-5-CARBOXYLATE;3-Methyl-[1,2,4]oxadiazole-5-carboxylic acid ethyl ester;1,2,4-Oxadiazole-5-carboxylic acid, 3-methyl-, ethyl ester
CBNumber
CB1764884
Molecular Formula
C6H8N2O3
Formula Weight
156.14
MOL File
40019-21-4.mol
More
Less

ETHYL 3-METHYL-1,2,4-OXADIAZOLE-5-CARBOXYLATE Property

Boiling point:
238.0±23.0 °C(Predicted)
Density 
1?+-.0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
-2.95±0.30(Predicted)
Appearance
Colorless to light yellow Liquid
More
Less

Safety

HazardClass 
IRRITANT
HS Code 
2934999090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
E939638
Product name
Ethyl3-Methyl-1,2,4-oxadiazole-5-carboxylate
Packaging
50mg
Price
$45
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0379436
Product name
ETHYL-3-METHYL-1,2,4-OXADIAZOLE-5-CARBOXYLATE
Purity
95.00%
Packaging
5MG
Price
$503.18
Updated
2021/12/16
Matrix Scientific
Product number
059158
Product name
3-Methyl-[1,2,4]oxadiazole-5-carboxylic acid ethyl ester
Purity
95+%
Packaging
5g
Price
$1005
Updated
2021/12/16
AK Scientific
Product number
5295AB
Product name
Ethyl3-methyl-1,2,4-oxadiazole-5-carboxylate
Packaging
25g
Price
$1563
Updated
2021/12/16
Matrix Scientific
Product number
059158
Product name
3-Methyl-[1,2,4]oxadiazole-5-carboxylic acid ethyl ester
Purity
95+%
Packaging
1g
Price
$227
Updated
2021/12/16
More
Less

ETHYL 3-METHYL-1,2,4-OXADIAZOLE-5-CARBOXYLATE Chemical Properties,Usage,Production

Synthesis

4755-77-5

22059-22-9

40019-21-4

General procedure for the synthesis of ethyl 3-methyl-1,2,4-oxadiazole-5-carboxylate from ethyl oxalyl chloride monoethyl ester and N'-hydroxyacetimidamide: At room temperature, (E)-N'-hydroxyacetimidamide (2.0 mmol, 1.0 g, 13.50 mmol, 1 equiv.) and pyridine (4.35 mL, 54.0 mmol, 4 equiv.) were dissolved in anhydrous dichloromethane ( 40 mL) and acetyl chloride (2.4 g, 18.0 mmol, 1.3 equiv) was added slowly. The reaction mixture was stirred under reflux conditions for 14 hours. After completion of the reaction, it was cooled to room temperature and the reaction was quenched with saturated ammonium chloride solution (30 mL). The aqueous phase was extracted with dichloromethane (2 x 50 mL). The organic phases were combined, washed with saturated sodium bicarbonate solution (50 mL), dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to afford ethyl 3-methyl-1,2,4-oxadiazole-5-carboxylate (2.2 mmol, 1.32 g, 8.45 mmol, 63% yield) as a yellow oil, which was used directly in the next step of the reaction.LCMS analysis showed a purity of 92%, retention time was 2.0 min, (M + H)+: 157.

References

[1] Patent: WO2013/50424, 2013, A1. Location in patent: Page/Page column 116

ETHYL 3-METHYL-1,2,4-OXADIAZOLE-5-CARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

ETHYL 3-METHYL-1,2,4-OXADIAZOLE-5-CARBOXYLATE Suppliers

China 52 India 2 United Kingdom 1 United States 8 Global 63
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
5000
Advantage
55
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
Advantage
60
Shanghai Litong Chemical Technology Co.,Ltd.
Tel
13598610367 0373-7129549
Fax
0373-8369699
Email
2468833170@qq.com
Country
China
ProdList
932
Advantage
58
Shanghai potentpharm CO.,Ltd
Tel
13524892556
Fax
(86) 21 51969655， QQ： 263541193
Email
sales-cn@potentpharm.com
Country
China
ProdList
1011
Advantage
55
Shanghai Chainpharm Bio-medical Technology Co., Ltd.
Tel
+86-021-61727342 13611721451
Fax
021-61294107
Email
chainpharm@163.com
Country
China
ProdList
980
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
ShangHai AmK Pharmaceutical Technology Co., Ltd.
Tel
微信 17321281695 18019252918
Fax
17321281695
Email
sale@amkchem.com
Country
China
ProdList
15136
Advantage
55
Tianjin Anhao Biological Technology Co., Ltd.
Tel
Email
sales@ahpharmatech.com
Country
China
ProdList
5734
Advantage
55
JW & Y Pharmlab Co., Ltd.
Tel
021-64340559 13651849907;
Fax
021- 64345308
Email
xinyu_shi@jwypharmlab.com.cn
Country
China
ProdList
12000
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shanghai Pingguo Pharmaceutical Co., Ltd.
Tel
021-20432229
Fax
QQ2412110556
Email
2412110556@qq.com
Country
China
ProdList
6017
Advantage
55
Wuxi AppTec
Tel
022-59987777 13552403979
Email
jia_guoqiang@wuxiapptec.com
Country
China
ProdList
22345
Advantage
58
Aikon International Limited
Tel
025-58859352 18068836627
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
16027
Advantage
58
Shanghai WangFa Chemical Technology Co., Ltd.
Tel
13918479294
Fax
-
Email
xiebenfa@163.com
Country
China
ProdList
4090
Advantage
58
Henan Aosman Biotechnology Co., LTD
Tel
0371-0371-61318675 17719817155
Fax
0371-61318675
Email
sales@xlinebio.com
Country
China
ProdList
2857
Advantage
58
Henan Alfachem Co.,Ltd.
Tel
0371-55051623 18137891487
Fax
QQ：2853979817
Email
2853979817@qq.com
Country
China
ProdList
9988
Advantage
58
Yujinpharma(Tianjin) Technology Co.,Ltd.
Tel
13370351217 kungfu1217@1
Fax
QQ1400885609
Email
kungfu1217@163.com
Country
China
ProdList
2720
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57422
Advantage
58
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
Shanghai Chenghe Medical Technology Co. Ltd.
Tel
021-021-54382182 18601603956
Email
18601603956@163.com
Country
China
ProdList
1255
Advantage
58
Shanghai zhigan biotechnology co., LTD
Tel
Email
zhiqianbio@126.com
Country
China
ProdList
19778
Advantage
58
Shanghai Rlavie Technology Co ltd
Tel
+86-021-67759270 +8617717059219
Fax
021-67759270
Email
sales@rlavie.com
Country
China
ProdList
1030
Advantage
58
Blocksynth Pharmaceutical Technology Co.,Ltd
Tel
0086-19817745290; +8619817745290
Email
bd@blocksynth.com
Country
China
ProdList
5661
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
+86-0571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52846
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30229
Advantage
58
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Email
sales@accelachem.com
Country
China
ProdList
10467
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
+86-29-81139210 +86-18192627656
Fax
+86-29-88380327
Email
1059@dideu.com
Country
China
ProdList
3588
Advantage
58
Taizhou Nanfeng Pharmaceutical Research Institute
Tel
nanfengdrug@163.com; 18616377689
Email
nanfengdrug@163.com
Country
China
ProdList
20009
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
029-029-81024372 17792795018
Fax
029-88380327
Email
1027@dideu.com
Country
China
ProdList
10003
Advantage
58
Shanghai Sunmonth Technology Co., LTD
Tel
15216675652
Email
xuanyuelj@163.com
Country
China
ProdList
2864
Advantage
58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.
Tel
021-51816796-820 13611835272
Fax
021-5161 3951
Email
sales2@sunwaypharm.com
Country
China
ProdList
44119
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 4008210725
Email
malulu@leyan.com
Country
China
ProdList
40000
Advantage
58
Bide Pharmatech Ltd.
Tel
400-6005915
Email
sales@picasso-e.com
Country
China
ProdList
39653
Advantage
58
Shanghai YuZn Pharm. Technology Co.,Ltd.
Tel
15921286451; 15921286451
Email
2010681527@qq.com
Country
China
ProdList
5182
Advantage
58
Suzhou Meishi Biotechnology Co., Ltd.
Tel
1173954148q
Email
meishipharma@126.com
Country
China
ProdList
20033
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 17801761073
Email
Gsiyu@solarbio.com
Country
China
ProdList
50464
Advantage
58
Shanghai He-H Chemical Technology Co., Ltd
Tel
18621911604
Email
987025641@qq.com
Country
China
ProdList
1063
Advantage
58
Suzhou Qihang Biotechnology Co., Ltd
Tel
18151111370
Email
1046215251@qq.com
Country
China
ProdList
8718
Advantage
58
Xi'an Ruicheng Pharmaceutical Technology Co., Ltd
Tel
17791728244
Email
3356623179@qq.com
Country
China
ProdList
879
Advantage
58
Shanghai Jieshikai Biotechnology Co. , Ltd.
Tel
021-57520305 13795461237
Email
zhuruyan@jskchem.com
Country
China
ProdList
49234
Advantage
58
Beijing Famozi Pharmaceutical Technology Co., Ltd
Tel
15811073878
Email
2559355526@qq.com
Country
China
ProdList
10000
Advantage
58
Shanghai Titan Enterprise Development Co., Ltd
Tel
16621224781
Email
syy@titansci.com
Country
China
ProdList
2896
Advantage
58
Ningbo Zhenyue Pharmaceutical Technology Co., Ltd
Tel
19817745290
Email
bd@blocksynth.com
Country
China
ProdList
5869
Advantage
58
Biosynth Biological Technology (Suzhou) Co Ltd
Tel
51288865780
Email
sales@biosynth.com
Country
China
ProdList
6051
Advantage
58
Nanjing Xinmeihe Pharmaceutical Co., Ltd.
Tel
025-57672321 13739186949
Fax
025-57672123
Email
yuanming@huashineltd.com
Country
China
ProdList
424
Advantage
58
Suzhou ARTK Medchem Co., Ltd.
Tel
+86-512-68323658 +86-18168183658
Email
sales1@artkmedchem.com
Country
China
ProdList
39002
Advantage
58
HANGZHOU LEAP CHEM CO., LTD.
Tel
+86-571-87711850
Email
market18@leapchem.com
Country
China
ProdList
43339
Advantage
58
Huadong Medicine (Xi'an)Bodyguard Pharmaceutical Co.,Ltd.
Tel
+86-029-86185165 +8618629664246
Email
guoyuan@eastchinapharm.com
Country
China
ProdList
1615
Advantage
58
GIHI CHEMICALS CO.,LIMITED
Tel
+8618058761490
Email
info@gihichemicals.com
Country
China
ProdList
49941
Advantage
58
More
Less

View Lastest Price from ETHYL 3-METHYL-1,2,4-OXADIAZOLE-5-CARBOXYLATE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
ethyl 3-?oxadiazole-? 40019-21-4
Price
US $1.00-100.00/KG
Min. Order
1KG
Purity
95%
Supply Ability
300KG
Release date
2024-08-19

40019-21-4, ETHYL 3-METHYL-1,2,4-OXADIAZOLE-5-CARBOXYLATERelated Search:

ETHYL 3-(2-CHLOROPHENOXY)METHYL-1,2,4-OXADIAZOLE-5 CARBOXYLATE ETHYL 3-(3,4-DIMETHOXYPHENYL)-1,2,4-OXADIAZOLE-5-CARBOXYLATE ETHYL 3-(2-THIENYL)-1,2,4-OXADIAZOLE-5-CARBOXYLATE ETHYL 3-[5-(CHLOROSULFONYL)-2-THIENYL]-1,2,4-OXADIAZOLE-5-CARBOXYLATE ETHYL 3-PHENYL-1,2,4-OXADIAZOLE-5-CARBOXYLATE ETHYL 3-(3-CHLOROPHENYL)-1,2,4-OXADIAZOLE-5-CARBOXYLATE 3-(4-NITRO-PHENYL)-[1,2,4]OXADIAZOLE-5-CARBOXYLIC ACID ETHYL ESTER 3-(4-CHLORO-PHENYL)-[1,2,4]OXADIAZOLE-5-CARBOXYLIC ACID ETHYL ESTER ETHYL 3-(3-METHOXYPHENYL)-1,2,4-OXADIAZOLE-5-CARBOXYLATE 1,2,4-OXADIAZOLE-5-CARBOXYLIC ACID, 3-[(5-METHYL-3-NITRO-1H-PYRAZOL-1-YL)METHYL]-, ETHYL ESTER ETHYL 3-[3-(TRIFLUOROMETHYL)PHENYL]-1,2,4-OXADIAZOLE-5-CARBOXYLATE 1,2,4-OXADIAZOLE-5-CARBOXYLIC ACID, 3-[(4-BROMO-3,5-DIMETHYL-1H-PYRAZOL-1-YL)METHYL]-, ETHYL ESTER 1,2,4-OXADIAZOLE-5-CARBOXYLIC ACID, 3-[(4-IODO-1H-PYRAZOL-1-YL)METHYL]-, ETHYL ESTER 3-P-TOLYL-[1,2,4]OXADIAZOLE-5-CARBOXYLIC ACID ETHYL ESTER ETHYL 3-([(4-CHLOROPHENYL)SULFONYL]METHYL)-1,2,4-OXADIAZOLE-5-CARBOXYLATE 1,2,4-OXADIAZOLE-5-CARBOXYLIC ACID, 3-[(PHENYLSULFONYL)METHYL]-, ETHYL ESTER 1,2,4-OXADIAZOLE-5-CARBOXYLIC ACID, 3-[4-(TRIFLUOROMETHYL)PHENYL]-, ETHYL ESTER

  • ETHYL 3-METHYL-1,2,4-OXADIAZOLE-5-CARBOXYLATE
  • 3-Methyl-[1,2,4]oxadiazole-5-carboxylic acid ethyl ester
  • 1,2,4-Oxadiazole-5-carboxylic acid, 3-methyl-, ethyl ester
  • ethyl 3-&#8203
  • oxadiazole-&#8203
  • ethyl 3-oxadiazole-
  • 40019-21-4