ChemicalBook > CAS DataBase List > 4-Hydroxy-L-phenylglycine

4-Hydroxy-L-phenylglycine

Product Name
4-Hydroxy-L-phenylglycine
CAS No.
32462-30-9
Chemical Name
4-Hydroxy-L-phenylglycine
Synonyms
(S)-2-AMino-2-(4-hydroxyphenyl)acetic acid;OXFENICINE;L-NORTYR;H-HPG-OH;UK-25842;L-(+)-Hydroxy;L-4-OH-Phg-OH;-(+)-2-phenyL;H-PHG(4-HYDROXY)-OH;4-Hydroxy-L<
CBNumber
CB1765553
Molecular Formula
C8H9NO3
Formula Weight
167.16
MOL File
32462-30-9.mol
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4-Hydroxy-L-phenylglycine Property

Melting point:
~240 °C (dec.)
alpha 
158 º (c=1% in 1M HCl)
Boiling point:
365.8±32.0 °C(Predicted)
Density 
1.396±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Aquous Acid (Slightly), DMSO (Slightly, Heated, Sonicated), Water (Slightly)
pka
2.15±0.10(Predicted)
form 
Solid
color 
White to Off-White
optical activity
[α]20/D +158±3°, c = 1% in 1 M HCl
BRN 
3589845
InChI
InChI=1/C8H9NO3/c9-7(8(11)12)5-1-3-6(10)4-2-5/h1-4,7,10H,9H2,(H,11,12)/t7-/s3
InChIKey
LJCWONGJFPCTTL-ZETCQYMHSA-N
SMILES
[C@@H](C1C=CC(O)=CC=1)(N)C(=O)O |&1:0,r|
CAS DataBase Reference
32462-30-9(CAS DataBase Reference)
EPA Substance Registry System
Benzeneacetic acid, .alpha.-amino-4-hydroxy-, (.alpha.S)- (32462-30-9)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
2922.50.4000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
56160
Product name
4-Hydroxy-L-phenylglycine
Purity
≥99.0% (NT)
Packaging
10g
Price
$131
Updated
2025/07/31
Sigma-Aldrich
Product number
56160
Product name
4-Hydroxy-L-phenylglycine
Purity
≥99.0% (NT)
Packaging
50g
Price
$352.1
Updated
2025/07/31
TCI Chemical
Product number
H1389
Product name
4-Hydroxy-L-(+)-2-phenylglycine
Purity
>99.0%(HPLC)(T)
Packaging
5g
Price
$97
Updated
2025/07/31
TCI Chemical
Product number
H1389
Product name
4-Hydroxy-L-(+)-2-phenylglycine
Purity
>99.0%(HPLC)(T)
Packaging
25g
Price
$292
Updated
2025/07/31
TRC
Product number
H949375
Product name
4-Hydroxy-L-(+)-2-phenylglycine
Packaging
100mg
Price
$45
Updated
2021/12/16
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4-Hydroxy-L-phenylglycine Chemical Properties,Usage,Production

Chemical Properties

White crystalline

Uses

Vasodilator.

Uses

4-Hydroxy-L-(+)-2-phenylglycine is a carnitine palmitoyltransferase-1 inhibitor. 4-Hydroxy-L-(+)-2-phenylglycine improves whole-body glucose tolerance and insulin sensitivity in high-fat diet-induced obese mouse with insulin resistance.

Definition

ChEBI: The L-enantiomer of 4-hydroxyphenylglycine.

reaction suitability

reaction type: solution phase peptide synthesis

in vivo

Oxfenicine (150 mg/kg, i.p., once daily for 3 weeks) treatment significantly reduces adiposity in high-fat diet rats[4].

Animal Model:Male Sprague-Dawley rats fed a high-fat (HF) diet[4]
Dosage:150 mg/kg
Administration:intraperitoneal injection (i.p.) once daily for 3 weeks
Result:Reduced whole-body fat oxidation, body weight, adiposity, and improved insulin sensitivity in HF-fed rats.

4-Hydroxy-L-phenylglycine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-Hydroxy-L-phenylglycine manufacturers

Career Henan Chemical Co
Product
4-Hydroxy-L-phenylglycine 32462-30-9
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
as request
Release date
2018-12-24

32462-30-9, 4-Hydroxy-L-phenylglycineRelated Search:

D-4-Hydroxyphenylglycine Methyl ester hydrochloride METHYL 2-AMINO-2-(4-HYDROXYPHENYL)ACETATE 4-HYDROXY-DL-PHENYLGLYCINE Potassium (R)-((3-ethoxy-1-methyl-3-oxoprop-1-enyl)amino)(4-hydroxyphenyl)acetate 4-Hydroxy-D-(-)-2-phenylglycine HYDROXY-N-PHENYLGLYCINE L-Phenylglycine Glycine Methyl 4-nitrobenzoate D-(-)-A-4-HYDROXYPHENYLGLYCINE DANE SALT METHYL POTASSIUM DL-P-Hydroxyphenylglycine 4-Hydroxy-D-phenylglycine methyl ester 4-carboxy-3-hydroxy-L-phenylglycine BOC-4-HYDROXY-D-PHENYLGLYCINE FMOC-4-HYDROXY-D-PHENYLGLYCINE parahydroxy phenylglycine dane salt 4-Hydroxy-L-phenylglycine methyl ester N-L-α-Aspartyl-4-hydroxy-D-phenylglycine 1-[(1S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2α-yl] ester

  • H-PHG(4-HYDROXY)-OH
  • H-HPG-OH
  • L-(+)-A-4-HYDROXYPHENYLGLYCINE
  • L-4-HYDROXYPHENYLGLYCINE
  • L-(+)-P-HYDROXYPHENYLGLYCINE
  • L-NORTYR
  • 4-HYDROXY-L-PHENYLGLYCINE
  • (S)-AMINO-(4-HYDROXY-PHENYL)-ACETIC ACID
  • OXFENICINE
  • L(+)4-Phydroxyphenylglycine
  • (2S)-amino(4-hydroxyphenyl)acetic acid
  • L-(+)-Hydroxy
  • L-(+)-alpha-4-hydroxyphenylglycine
  • L-4-OH-Phg-OH
  • 4-HYDROXY-L-PHENYLGLYCINE 99+%
  • L-P-HYDROXYPHENYGLYCINE
  • (2S)-2-Amino-2-(4-hydroxyphenyl)acetic acid
  • (S)-2-(4-Hydroxyphenyl)glycine
  • (S)-α-Amino-4-hydroxybenzeneacetic acid
  • UK-25842
  • (S)-2-AMino-2-(4-hydroxyphenyl)acetic acid
  • 4-Hydroxy-L-(+)-2-phenylglycine
  • 4-Hydroxy-L-phenylglycine >=99.0% (NT)
  • 4-Hydroxy-<small>L</small>-(+)-2-phenylglycine
  • Benzeneacetic acid, a-amino-4-hydroxy-, (aS)-
  • 4-Hydroxy-L-(+)-2-phenylglycine&gt
  • Benzeneacetic acid, α-amino-4-hydroxy-, (αS)-
  • -(+)-2-phenyL
  • (2S)-2-amino-2-(4-hydroxyphenyl)aceticaci
  • L-(+)-2-(4-Hydroxyphenyl)glycine
  • 4-Hydroxy-L-phenylglycine USP/EP/BP
  • (L)-(+)-α-4-hydroxyphenyl glycine
  • 4-Hydroxy-L-phenylglycine,97%
  • 4-Hydroxy-<small>L<
  • 4-Hydroxy-<sc>L</sc>-phenylglycine
  • (2S)-2-amino-2-(4-hydroxyphenyl)acetic acid - [A86489]
  • 32462-30-9
  • Peptide Synthesis
  • Phenylglycine Derivatives
  • Specialty Synthesis
  • Unnatural Amino Acid Derivatives
  • Amino ACIDS SERIES