2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE
- Product Name
- 2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE
- CAS No.
- 568544-03-6
- Chemical Name
- 2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE
- Synonyms
- GSTO1-IN-1;GSTO1 inhibitor 1;2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE;2-Chloro-N-(4-chloro-3-(N,N-dimethylsulfamoyl)phenyl)acetamide;2-Chloro-N-[4-chloro-3-[(dimethylamino)sulfonyl]phenyl]acetamide;Acetamide, 2-chloro-N-[4-chloro-3-[(dimethylamino)sulfonyl]phenyl]-;GSTs,GSTO1IN1,Glutathione transferases,inhibit,Inhibitor,Gutathione S-transferase,GSTO1 IN 1,GSTO-1-IN-1
- CBNumber
- CB1774579
- Molecular Formula
- C10H12Cl2N2O3S
- Formula Weight
- 311.18
- MOL File
- Mol file
2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- Solid
- color
- Light yellow to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CS-0042397
- Product name
- GSTO1-IN-1
- Purity
- 99.12%
- Packaging
- 100mg
- Price
- $380
- Updated
- 2021/12/16
- Product number
- HCH0058363
- Product name
- 2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $692.46
- Updated
- 2021/12/16
- Product number
- 0184CM
- Product name
- 2-Chloro-N-[4-chloro-3-(dimethylsulfamoyl)phenyl]acetamide
- Packaging
- 2.5g
- Price
- $784
- Updated
- 2021/12/16
- Product number
- HCH0058363
- Product name
- 2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE
- Purity
- 95.00%
- Packaging
- 2.5G
- Price
- $932.6
- Updated
- 2021/12/16
- Product number
- HCH0058363
- Product name
- 2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $1114.58
- Updated
- 2021/12/16
2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE Chemical Properties,Usage,Production
Biological Activity
GSTO1-IN-1 is a potent glutathione S-transferase omega 1 (GSTO1) inhibitor with IC50 of 31 nM.
in vitro
GSTO1-IN-1 (C1-27) potently inhibits GSTO1 enzyme activity with an IC 50 value of 31 nM. GSTO1-IN-1 also potently competes with 5-chloromethylfluorescein diacetate (CMFDA) for binding to recombinant protein, as well as endogenous GSTO1 in the milieu of a soluble proteome. HCT116 cells treated with GSTO1-IN-1 also show a decrease in cell viability in a dose-dependent manner. GSTO1-IN-1 inhibits the clonogenic survival of HCT116 cells at sub-micromolar concentrations.
target
IC50: 31 nM (GSTO1)
2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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