ChemicalBook > CAS DataBase List > BAY-784
BAY-784
- Product Name
- BAY-784
- CAS No.
- 1631164-24-3
- Chemical Name
- BAY-784
- Synonyms
- BAY-784;BAY1214784;BAY784,BAY 784;(S)-N-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-2-cyclopropyl-1-((4-fluorophenyl)sulfonyl)-;Spiro[3H-indole-3,4'-[4H]thiopyran]-5-carboxamide, N-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]methyl]-2-cyclopropyl-1-[(4-fluorophenyl)sulfonyl]-1,2,2',3',5',6'-hexahydro-, 1',1'-dioxide, (2S)-
- CBNumber
- CB18054323
- Molecular Formula
- C29H26ClF4N3O5S2
- Formula Weight
- 672.11
- MOL File
- 1631164-24-3.mol
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BAY-784 Property
- Density
- 1.60±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: 2mg/mL, clear
- pka
- 12.47±0.40(Predicted)
- form
- powder
- color
- white to beige
- optical activity
- [α]/D -120 to -100°, c =0.5 in chloroform-d
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BAY-784 Chemical Properties,Usage,Production
Biological Activity
BAY-784 is an orally available, non-toxic, potent, and selective antagonist of human Gonadotropin-Releasing Hormone Receptor [hGnRH-R], which is potently active in other species including rate, dogs and cynomolgus monkey. It partially lowered plasma luteinizing hormone levels in humans. BAY-784 exhibits favorable drug metabolism and pharmacokinetic (DMPK) profile thus is suitable for in vivo studies.
BAY-784 Preparation Products And Raw materials
Raw materials
Preparation Products
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