MRGPRX1 agonist 1

Product Name: MRGPRX1 agonist 1
CAS No.: 2377379-39-8
Chemical Name: MRGPRX1 agonist 1
Synonyms: BUN79398;MRGPRX1 agonist 1;MRGPRX1 agonist 1, 10 mM in DMSO;MRGPRX1 agonist 1,Inhibitor,MRGPRX-1 agonist 1,inhibit;N-(2-((1-Aminoisoquinolin-6-yl)oxy)-4-methylphenyl)-2-methoxybenzenesulfonamide;Benzenesulfonamide, N-[2-[(1-amino-6-isoquinolinyl)oxy]-4-methylphenyl]-2-methoxy-
CBNumber: CB18054464
Molecular Formula: C23H21N3O4S
Formula Weight: 435.5
MOL File: 2377379-39-8.mol

More

Less

MRGPRX1 agonist 1 Property

Boiling point:: 642.0±65.0 °C(Predicted)
Density: 1.365±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 130 mg/mL (298.51 mM; Need ultrasonic)
pka: 8.81±0.10(Predicted)
form: Solid
color: White to yellow
InChI: InChI=1S/C23H21N3O4S/c1-15-7-10-19(26-31(27,28)22-6-4-3-5-20(22)29-2)21(13-15)30-17-8-9-18-16(14-17)11-12-25-23(18)24/h3-14,26H,1-2H3,(H2,24,25)
InChIKey: BWEJNHRMGZUMNU-UHFFFAOYSA-N
SMILES: C1(S(NC2=CC=C(C)C=C2OC2C=CC3=C(C=2)C=CN=C3N)(=O)=O)=CC=CC=C1OC

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

MRGPRX1 agonist 1 Chemical Properties,Usage,Production

Uses

MRGPRX1 agonist 1 is a highly potent agonist of MRGPRX1 (Mas-related G-protein-coupled receptor X1), with an EC50 of 50 nM, and is inactive on MRGPRC11. Analgesic effect[1].

Biological Activity

MRGPRX1 agonist 1 is a highly potent agonist of MRGPRX1 (Mas-related G-protein-coupled receptor X1), with an EC50 of 50 nM, and is inactive on MRGPRC11. Analgesic effect[1].

References

[1]. Prchalová E, et al. Discovery of Benzamidine- and 1-Aminoisoquinoline-Based Human MAS-Related G-Protein-Coupled Receptor X1 (MRGPRX1) Agonists. J Med Chem. 2019 Sep 26;62(18):8631-8641.

MRGPRX1 agonist 1 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

MRGPRX1 agonist 1 Suppliers

China 34 United States 2 Global 36

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8000
Advantage: 62

Shanghai Rechem science Co., Ltd.

Tel: 021-31433387 15618786686
Fax: QQ:1369748377
Email: sales@rechemscience.com
Country: China
ProdList: 2961
Advantage: 58

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 9531
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32470
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

ShangHai ChuanQian Chemcial Technique Centre

Tel: 15869524721
Email: 3525679403@qq.com
Country: China
ProdList: 4899
Advantage: 58

Chunchuang (Wuhan) Technology Co., Ltd

Tel: 15727060112
Email: yutianchun2007@126.com
Country: China
ProdList: 9815
Advantage: 58

cjbscvictory

Tel: 13348960310
Email: 3003867561@qq.com
Country: China
ProdList: 10503
Advantage: 58

2377379-39-8, MRGPRX1 agonist 1Related Search:

MRGPRX1 agonist 1

MRGPRX1 agonist 1,Inhibitor,MRGPRX-1 agonist 1,inhibit

Benzenesulfonamide, N-[2-[(1-amino-6-isoquinolinyl)oxy]-4-methylphenyl]-2-methoxy-

BUN79398

N-(2-((1-Aminoisoquinolin-6-yl)oxy)-4-methylphenyl)-2-methoxybenzenesulfonamide

MRGPRX1 agonist 1, 10 mM in DMSO

2377379-39-8