GRP-60367

Product Name: GRP-60367
CAS No.: 1309241-34-6
Chemical Name: GRP-60367
Synonyms: GRP-60367;GRP-60367, 10 mM in DMSO;N-[2-(2,5-dimethylphenoxy)ethyl]-1-(pyridine-4-carbonyl)piperidin-4-amine;GRP60367,inhibit,strain,RABV,GRP 60367,rabies,Inhibitor,GRP-60367,virus,entry;(4-((2-(2,5-Dimethylphenoxy)ethyl)amino)piperidin-1-yl)(pyridin-4-yl)methanone;Methanone, [4-[[2-(2,5-dimethylphenoxy)ethyl]amino]-1-piperidinyl]-4-pyridinyl-
CBNumber: CB18059126
Molecular Formula: C21H27N3O2
Formula Weight: 353.46
MOL File: 1309241-34-6.mol

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GRP-60367 Property

Boiling point:: 547.9±50.0 °C(Predicted)
Density: 1.16±0.1 g/cm3(Predicted)
pka: 8.44±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Ambeed

Product number: A1362216
Product name: (4-((2-(2,5-Dimethylphenoxy)ethyl)amino)piperidin-1-yl)(pyridin-4-yl)methanone
Purity: 98%
Packaging: 1mg
Price: $50
Updated: 2021/12/16

CSNpharm

Product number: CSN27669
Product name: GRP60367
Packaging: 1mg
Price: $60
Updated: 2021/12/16

Ambeed

Product number: A1362216
Product name: (4-((2-(2,5-Dimethylphenoxy)ethyl)amino)piperidin-1-yl)(pyridin-4-yl)methanone
Purity: 98%
Packaging: 5mg
Price: $90
Updated: 2021/12/16

CSNpharm

Product number: CSN27669
Product name: GRP60367
Packaging: 5mg
Price: $100
Updated: 2021/12/16

Ambeed

Product number: A1362216
Product name: (4-((2-(2,5-Dimethylphenoxy)ethyl)amino)piperidin-1-yl)(pyridin-4-yl)methanone
Purity: 98%
Packaging: 10mg
Price: $160
Updated: 2021/12/16

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GRP-60367 Chemical Properties,Usage,Production

Uses

GRP-60367 is a first-in-class small-molecule rabies virus (RABV) entry inhibitor with nanomolar potency against some RABV strains[1].

Biological Activity

GRP-60367 is a first-in-class small molecule rabies virus (RABV) entry inhibitor with nanomolar efficacy against certain RABV strains.

in vitro

GRP-60367 inhibits entry of a subset of RABV strains. GRP-60367 shows specific and potent anti-RABV activity of the scaffold, returning in dose-response assays EC ₅₀ s ranging from 2 to 52 nM on different host cell lines.

target

RABV

References

[1] Venice Du Pont, et al. Identification and Characterization of a Small-Molecule Rabies Virus Entry Inhibitor. J Virol. 2020 Jun 16;94(13):e00321-20. DOI:10.1128/JVI.00321-20

GRP-60367 Preparation Products And Raw materials

Raw materials

Preparation Products

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GRP-60367 Suppliers

China 25 United States 5 Global 30

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
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Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
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Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
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ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8000
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Shanghai Rechem science Co., Ltd.

Tel: 021-31433387 15618786686
Fax: QQ:1369748377
Email: sales@rechemscience.com
Country: China
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Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 9531
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Shanghai Yu Ben Biotechnology Co., Ltd.

Tel: 021-61350663 15502154572
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Email: 1639466865@qq.com
Country: China
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
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InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
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Chunchuang (Wuhan) Technology Co., Ltd

Tel: 15727060112
Email: yutianchun2007@126.com
Country: China
ProdList: 9815
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1309241-34-6, GRP-60367Related Search:

GRP-60367

(4-((2-(2,5-Dimethylphenoxy)ethyl)amino)piperidin-1-yl)(pyridin-4-yl)methanone

GRP60367,inhibit,strain,RABV,GRP 60367,rabies,Inhibitor,GRP-60367,virus,entry

Methanone, [4-[[2-(2,5-dimethylphenoxy)ethyl]amino]-1-piperidinyl]-4-pyridinyl-

N-[2-(2,5-dimethylphenoxy)ethyl]-1-(pyridine-4-carbonyl)piperidin-4-amine

GRP-60367, 10 mM in DMSO

1309241-34-6