Spiro[6,16-(epithiopropanoxymethano)-7,13-imino-12H-1,3-dioxolo[7,8]isoquino[3,2-b][3]benzazocine-20,1'(2'H)-isoquinolin]-19-one, 3',4',6,6a,7,13,14,16-octahydro-5,6',8,14-tetrahydroxy-7',9-dimethoxy-4,10,23-trimethyl-, (1'R,6R,6aR,7R,13S,14S,16R)- (9CI)

Product Name
Spiro[6,16-(epithiopropanoxymethano)-7,13-imino-12H-1,3-dioxolo[7,8]isoquino[3,2-b][3]benzazocine-20,1'(2'H)-isoquinolin]-19-one, 3',4',6,6a,7,13,14,16-octahydro-5,6',8,14-tetrahydroxy-7',9-dimethoxy-4,10,23-trimethyl-, (1'R,6R,6aR,7R,13S,14S,16R)- (9CI)
CAS No.
493024-42-3
Chemical Name
Spiro[6,16-(epithiopropanoxymethano)-7,13-imino-12H-1,3-dioxolo[7,8]isoquino[3,2-b][3]benzazocine-20,1'(2'H)-isoquinolin]-19-one, 3',4',6,6a,7,13,14,16-octahydro-5,6',8,14-tetrahydroxy-7',9-dimethoxy-4,10,23-trimethyl-, (1'R,6R,6aR,7R,13S,14S,16R)- (9CI)
Synonyms
ET-701;Trabectedin Impurity 2;Spiro[6,16-(epithiopropanoxymethano)-7,13-imino-12H-1,3-dioxolo[7,8]isoquino[3,2-b][3]benzazocine-20,1'(2'H)-isoquinolin]-19-one, 3',4',6,6a,7,13,14,16-octahydro-5,6',8,14-tetrahydroxy-7',9-dimethoxy-4,10,23-trimethyl-, (1'R,6R,6aR,7R,13S,14S,16R)- (9CI)
CBNumber
CB18124570
Molecular Formula
C37H41N3O10S
Formula Weight
719.81
MOL File
493024-42-3.mol
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Spiro[6,16-(epithiopropanoxymethano)-7,13-imino-12H-1,3-dioxolo[7,8]isoquino[3,2-b][3]benzazocine-20,1'(2'H)-isoquinolin]-19-one, 3',4',6,6a,7,13,14,16-octahydro-5,6',8,14-tetrahydroxy-7',9-dimethoxy-4,10,23-trimethyl-, (1'R,6R,6aR,7R,13S,14S,16R)- (9CI) Property

Density 
1.59±0.1 g/cm3(Predicted)
pka
9.70±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

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Spiro[6,16-(epithiopropanoxymethano)-7,13-imino-12H-1,3-dioxolo[7,8]isoquino[3,2-b][3]benzazocine-20,1'(2'H)-isoquinolin]-19-one, 3',4',6,6a,7,13,14,16-octahydro-5,6',8,14-tetrahydroxy-7',9-dimethoxy-4,10,23-trimethyl-, (1'R,6R,6aR,7R,13S,14S,16R)- (9CI) Chemical Properties,Usage,Production

Uses

Et 701 is related to Trabectedin (T703500) an alkaloid with antitumor activity isolated from the Caribbean tunicate, Ecteinascidin turbinata. Et 701 is formed by the ester hydrolysis Trabectedin in the liver.

Spiro[6,16-(epithiopropanoxymethano)-7,13-imino-12H-1,3-dioxolo[7,8]isoquino[3,2-b][3]benzazocine-20,1'(2'H)-isoquinolin]-19-one, 3',4',6,6a,7,13,14,16-octahydro-5,6',8,14-tetrahydroxy-7',9-dimethoxy-4,10,23-trimethyl-, (1'R,6R,6aR,7R,13S,14S,16R)- (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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Spiro[6,16-(epithiopropanoxymethano)-7,13-imino-12H-1,3-dioxolo[7,8]isoquino[3,2-b][3]benzazocine-20,1'(2'H)-isoquinolin]-19-one, 3',4',6,6a,7,13,14,16-octahydro-5,6',8,14-tetrahydroxy-7',9-dimethoxy-4,10,23-trimethyl-, (1'R,6R,6aR,7R,13S,14S,16R)- (9CI) Suppliers

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493024-42-3, Spiro[6,16-(epithiopropanoxymethano)-7,13-imino-12H-1,3-dioxolo[7,8]isoquino[3,2-b][3]benzazocine-20,1'(2'H)-isoquinolin]-19-one, 3',4',6,6a,7,13,14,16-octahydro-5,6',8,14-tetrahydroxy-7',9-dimethoxy-4,10,23-trimethyl-, (1'R,6R,6aR,7R,13S,14S,16R)- (9CI)Related Search:

Spiro[6,16-(epithiopropanoxymethano)-7,13-imino-12H-1,3-dioxolo[7,8]isoquino[3,2-b][3]benzazocine-20,1'(2'H)-isoquinolin]-19-one, 5-(acetyloxy)-3',4',6,6a,7,13,14,16-octahydro-6',8-dihydroxy-7',9-dimethoxy-4,10,23-trimethyl-, (1'R,6R,6aR,7R,13S,16R)- (9CI) ecteinascidin 743

  • Spiro[6,16-(epithiopropanoxymethano)-7,13-imino-12H-1,3-dioxolo[7,8]isoquino[3,2-b][3]benzazocine-20,1'(2'H)-isoquinolin]-19-one, 3',4',6,6a,7,13,14,16-octahydro-5,6',8,14-tetrahydroxy-7',9-dimethoxy-4,10,23-trimethyl-, (1'R,6R,6aR,7R,13S,14S,16R)- (9CI)
  • Trabectedin Impurity 2
  • ET-701
  • 493024-42-3
  • C37H41N3O10S