SSD114 hydrochloride
- Product Name
- SSD114 hydrochloride
- CAS No.
- 2319790-02-6
- Chemical Name
- SSD114 hydrochloride
- Synonyms
- SSD114 HCl, 10 mM in DMSO;SSD114 HCl (SSD114 Hydrochloride);N-Cyclohexyl-4-methoxy-6-(4-(trifluoromethyl)phenyl)pyrimidin-2-amine hydrochloride
- CBNumber
- CB18280362
- Molecular Formula
- C18H21ClF3N3O
- Formula Weight
- 387.83
- MOL File
- 2319790-02-6.mol
SSD114 hydrochloride Property
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- CS-8202
- Product name
- SSD114hydrochloride
- Purity
- 99.07%
- Packaging
- 1mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- CS-8202
- Product name
- SSD114hydrochloride
- Purity
- 99.07%
- Packaging
- 5mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- CS-8202
- Product name
- SSD114hydrochloride
- Purity
- 99.07%
- Packaging
- 10mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- CS-8202
- Product name
- SSD114hydrochloride
- Purity
- 99.07%
- Packaging
- 25mg
- Price
- $250
- Updated
- 2021/12/16
- Product number
- CS-8202
- Product name
- SSD114hydrochloride
- Purity
- 99.07%
- Packaging
- 50mg
- Price
- $450
- Updated
- 2021/12/16
SSD114 hydrochloride Chemical Properties,Usage,Production
Uses
SSD114 hydrochloride is a novel GABAB receptor positive allosteric modulator.
in vivo
The onset of loss of righting reflex (LORR) is reduced by pretreatment with SSD114 hydrochloride [F(5,30)=4.55, P<0.005]. Post hoc analysis indicates that the onset of LORR is significantly lower in mouse groups pretreated with doses of SSD114 hydrochloride equal to or higher than 10 mg/kg than in vehicle-treated mice. The duration of LORR is increased by pretreatment with SSD114 hydrochloride [F(5,30)=4.81, P<0.005]. Post hoc analysis indicates that the duration of LORR is significantly longer in mouse groups pretreated with 10 and 100 mg/kg SSD114 hydrochloride than in vehicle-treated mice[1].
References
[1] Porcu A, et al. In vitro and in vivo pharmacological characterization of SSD114, a novel GABAB positive allosteric modulator. Eur J Pharmacol. 2016 Nov 15;791:115-123. DOI:10.1016/j.ejphar.2016.08.032
SSD114 hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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