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3-BROMOBENZENE-1,2-DIOL

Product Name
3-BROMOBENZENE-1,2-DIOL
CAS No.
14381-51-2
Chemical Name
3-BROMOBENZENE-1,2-DIOL
Synonyms
3-Bromopyrocatechol;3-Bromocatechol >3-BROMOBENZENE-1,2-DIOL;3-bromo-1,2-benzenediol;1,2-Benzenediol, 3-bromo-;Phloroglucinol Impurity 30;2,3-dihydroxy-broMobenzene;1-Bromo-2,3-dihydroxybenzene;3-BROMOBENZENE-1,2-DIOL ISO 9001：2015 REACH;3-bromobenzene-1,2-diol ( = 3-Bromocatechol)
CBNumber
CB1841028
Molecular Formula
C6H5BrO2
Formula Weight
189.01
MOL File
14381-51-2.mol
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3-BROMOBENZENE-1,2-DIOL Property

Melting point:
40-41℃
Boiling point:
243℃
Density 
1.844
Flash point:
101℃
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Soluble in organic solvents.
form 
powder to crystal
pka
8.26±0.10(Predicted)
color 
White to Gray to Brown
InChI
InChI=1S/C6H5BrO2/c7-4-2-1-3-5(8)6(4)9/h1-3,8-9H
InChIKey
JPBDMIWPTFDFEU-UHFFFAOYSA-N
SMILES
C1(O)=CC=CC(Br)=C1O
CAS DataBase Reference
14381-51-2
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Safety

HS Code 
2908190090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
B3710
Product name
3-Bromocatechol
Purity
>98.0%(GC)
Packaging
1g
Price
$57
Updated
2025/07/31
TCI Chemical
Product number
B3710
Product name
3-Bromocatechol
Purity
>98.0%(GC)
Packaging
5g
Price
$263
Updated
2025/07/31
TRC
Product number
B678093
Product name
3-Bromobenzene-1,2-diol
Packaging
50mg
Price
$60
Updated
2021/12/16
ChemScene
Product number
CS-W006003
Product name
3-Bromobenzene-1,2-diol
Purity
99.17%
Packaging
1g
Price
$27
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB153684
Product name
3-Bromocatechol
Packaging
250mg
Price
$50
Updated
2021/12/16
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3-BROMOBENZENE-1,2-DIOL Chemical Properties,Usage,Production

Chemical Properties

Needle-like crystals

Uses

3-Bromocatechol, is used as a drug and agrochemicals intermediate, Pharmaceutical intermediate.

Synthesis Reference(s)

Journal of the American Chemical Society, 69, p. 2241, 1947 DOI: 10.1021/ja01201a514

Synthesis

28165-49-3

14381-51-2

The general procedure for the synthesis of 3-bromocatechol from 2-bromo-6-methoxyphenol was as follows: to an anhydrous dichloromethane (40 mL) solution of 2-bromo-6-methoxyphenol (8.00 g, 39.4 mmol) was slowly added boron tribromide (1 M in dichloromethane, 43.1 mmol, 43.0 mL) at -78 °C. The reaction mixture was stirred for 1 hour at room temperature, then poured into ice water and continued to stir for 30 minutes. Subsequently, extraction was performed with dichloromethane (3 x 30 mL). The organic layers were combined, dried with anhydrous magnesium sulfate, and concentrated to give the target product 3-bromocatechol (6.90 g, 93% yield) as a brown oil. Thin layer chromatography (TLC) analysis showed an Rf value of 0.2 (unfolding agent: toluene/ethyl acetate = 9:1). The 1H NMR data of the product were as follows: δH 5.60 (1H, broad single peak, OH), 5.69 (1H, broad single peak, OH), 6.72 (1H, double peak, J=8.1 Hz), 6.87 (1H, double peak, J=1.5,8.1 Hz), 7.00 (1H, double peak, J=1.5,8.1 Hz); 13C NMR data: δC 109.5, 114.9, 121.9, 123.3, 140.3, 144.5.The 1H NMR spectra of the products were in agreement with the literature reports.

References

[1] Organic Letters, 2016, vol. 18, # 15, p. 3726 - 3729
[2] Tetrahedron, 2011, vol. 67, # 34, p. 6308 - 6315
[3] Tetrahedron Letters, 1995, vol. 36, # 36, p. 6413 - 6414

3-BROMOBENZENE-1,2-DIOL Preparation Products And Raw materials

Raw materials

Preparation Products

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3-BROMOBENZENE-1,2-DIOL Suppliers

Americas 1 China 145 Europe 1 France 1 India 4 Japan 1 South Korea 1 Ukraine 1 United Kingdom 2 United States 11 Global 168
FCH Group
Tel
--
Fax
--
Email
info@fchgroup.net
Country
Ukraine
ProdList
721
Advantage
0
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View Lastest Price from 3-BROMOBENZENE-1,2-DIOL manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
3-BROMOBENZENE-1,2-DIOL 14381-51-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
3-BROMOBENZENE-1,2-DIOL 14381-51-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08
Career Henan Chemical Co
Product
3-BROMOBENZENE-1,2-DIOL 14381-51-2
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2019-12-31

14381-51-2, 3-BROMOBENZENE-1,2-DIOLRelated Search:

TETRABROMOCATECHOL 3-BROMO-4-HYDROXY-5-METHOXYCINNAMIC ACID 2,3-DIBROMO-4-HYDROXY-5-METHOXYBENZALDEHYDE 7-Bromobenzo[1,3]dioxole-5-carbaldehyde 5-Bromovanillin Bromopyrogallol Red 4-Bromobenzene-1,3-diol 2-Bromobenzene-1,4-diol Catechol 3-BROMO-4,5-DIMETHOXYBENZOIC ACID 2-BROMO-4-(HYDROXYMETHYL)-6-METHOXYPHENOL 3-BROMO-4-HYDROXY-5-METHOXYPHENYLACETONITRILE 2,3-DIBROMO-4,5-DIHYDROXYBENZALDEHYDE 5-BROMOVERATRALDEHYDE R(+)-6-BROMO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE 3-BROMO-4-HYDROXY-5-METHOXYPHENYLACETIC ACID 5-BROMOPROTOCATECHUALDEHYDE 2-bromobenzene-1,3-diol

  • 3-BROMOBENZENE-1,2-DIOL
  • 2,3-dihydroxy-broMobenzene
  • 1-Bromo-2,3-dihydroxybenzene
  • 3-Bromopyrocatechol
  • Phloroglucinol Impurity 30
  • 3-Bromocatechol &gt
  • 1,2-Benzenediol, 3-bromo-
  • 3-bromo-1,2-benzenediol
  • 3-BROMOBENZENE-1,2-DIOL ISO 9001：2015 REACH
  • 3-bromobenzene-1,2-diol ( = 3-Bromocatechol)
  • 14381-51-2
  • 1