Beclamide
- Product Name
- Beclamide
- CAS No.
- 501-68-8
- Chemical Name
- Beclamide
- Synonyms
- Neurace;Hibicon;Nidrane;BeklaMid;Neuracen;Posedrine;Chlorakon;NSC 67062;Beclamide;ChloroethylphenaMide
- CBNumber
- CB1875348
- Molecular Formula
- C10H12ClNO
- Formula Weight
- 197.66
- MOL File
- 501-68-8.mol
Beclamide Property
- Melting point:
- 94°
- Boiling point:
- 386.9±35.0 °C(Predicted)
- Density
- 1.1363 (rough estimate)
- refractive index
- 1.5330 (estimate)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 15.55±0.46(Predicted)
- color
- Large crystals from MeOH
Safety
- HS Code
- 2924297099
- Toxicity
- LD50 orl-rat: 3200 mg/kg JPETAB 107,403,53
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- B119400
- Product name
- Beclamide
- Packaging
- 2.5g
- Price
- $145
- Updated
- 2021/12/16
- Product number
- 003129
- Product name
- Beclamide
- Packaging
- 2.5g
- Price
- $460
- Updated
- 2021/12/16
- Product number
- FB18150
- Product name
- N-(Benzyl)-3-Chloro-Propionamide
- Packaging
- 2g
- Price
- $480
- Updated
- 2021/12/16
- Product number
- 54063
- Product name
- Beclamide
- Packaging
- 2.5g
- Price
- $650
- Updated
- 2021/12/16
- Product number
- HCH0026827
- Product name
- N-BENZYL-3-CHLORO-PROPIONAMIDE
- Purity
- 95.00%
- Packaging
- 2.5G
- Price
- $880
- Updated
- 2021/12/16
Beclamide Chemical Properties,Usage,Production
Originator
Posedrine,Biosa,Switz.
Uses
Beclamide is a chlorinated benzylpropanamide used as an anticonvulsant drug. It is used in the treatment of tonic-clonic seizyres and has sedative properties.
Uses
anticonvulsant, antiepileptic
Definition
ChEBI: Beclamide is a member of benzenes.
Manufacturing Process
A 100 gallon lined jacketed kettle provided with cooling is charged with 100 lb
of benzylamine and 150 liters of water. The mixture is cooled to 5°C and with
stirring 119 lb of β-chloropropionyl chloride and a solution of 45 lb of sodium
hydroxide pellets in 40 liters of water are added simultaneously at such a rate
that the temperature does not exceed 10°C. During this period the pH of the mixture should be on the alkaline side but below pH 9.5. When the addition is
complete the pH should be about 8. The mixture is stirred overnight in the
cold, and the solid product is filtered. The filter cake is reslurred with about 80
gallons of water, filtered, and air-dried. Yield, 128 pounds.
The crude material is recrystallized by dissolving it in the minimal quantity of
hot methanol (about 50 gallons), adding Norite, and filtering hot. Upon
cooling slowly (finally to about 5°C) large crystals separate: they are filtered
and air-dried. Yield, 109 pounds. Melting point 92° to 93°C.
Therapeutic Function
Anticonvulsant
Safety Profile
Moderately toxic by ingestion,intraperitoneal and intravenous routes. When heated todecomposition it emits very toxic fumes of Cl- and NOx.An anticonvulsant.
Beclamide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Beclamide manufacturers
- Product
- Beclamide 501-68-8
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-09