ChemicalBook > CAS DataBase List > 3-(o-chlorophenyl)-3-hydroxy-3-phenylpropiononitrile
3-(o-chlorophenyl)-3-hydroxy-3-phenylpropiononitrile
- Product Name
- 3-(o-chlorophenyl)-3-hydroxy-3-phenylpropiononitrile
- CAS No.
- 35173-29-6
- Chemical Name
- 3-(o-chlorophenyl)-3-hydroxy-3-phenylpropiononitrile
- Synonyms
- 1-(o-Chlorophenyl)-2-cyano-1-phenyl-ethenol;2-Chloro-hydroxy-phenyl benzene-propanenitrile;Benzenepropanenitrile, 2-chloro-β-hydroxy-β-phenyl-;3-(2-chlorophenyl)-3-hydroxy-3-phenylpropanenitrile;3-(O-CHLOROPHENYL)-3-HYDROXY-3-PHENYL PROPIONITRILE;3-(o-chlorophenyl)-3-hydroxy-3-phenylpropiononitrile
- CBNumber
- CB1884506
- Molecular Formula
- C15H12ClNO
- Formula Weight
- 257.71
- MOL File
- 35173-29-6.mol
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3-(o-chlorophenyl)-3-hydroxy-3-phenylpropiononitrile Property
- Melting point:
- 90-92 °C
- Boiling point:
- 482.0±40.0 °C(Predicted)
- Density
- 1.253±0.06 g/cm3(Predicted)
- pka
- 11.82±0.29(Predicted)
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- HCH0358129
- Product name
- 3-(O-CHLOROPHENYL)-3-HYDROXY-3-PHENYLPROPIONONITRILE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.83
- Updated
- 2021/12/16
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3-(o-chlorophenyl)-3-hydroxy-3-phenylpropiononitrile Chemical Properties,Usage,Production
Chemical Properties
Crystalline compounds. Melting point 88-91 ℃.
Uses
3-(o-chlorophenyl)-3-hydroxy-3-phenylpropiononitrile is the intermediate of the enemy cough.
Synthesis
Use o-chlorobenzoic acid to chlorinate with thionyl chloride to generate o-chlorobenzoyl chloride, which is then condensed with benzene under the participation of aluminum trichloride to obtain o-chlorobenzoyl. 3-(O-chlorophenyl)-3-hydroxy-3-phenylpropiononitrile is obtained by condensing the latter with acetonitrile under the action of sodium amide.
3-(o-chlorophenyl)-3-hydroxy-3-phenylpropiononitrile Preparation Products And Raw materials
Raw materials
(2-Chlorophenyl)phenyl-methanone
2-Chlorobenzoic acid
Thionyl chloride
Aluminium chloride hexahydrate
Sodium amide
2-Chlorobenzoyl chloride
Preparation Products
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