2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate)

Product Name: 2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate)
CAS No.: 57781-14-3
Chemical Name: 2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate)
Synonyms: Topicon;THS 201;Haloart;Ccris 2685;Einecs 260-951-4;halopredone acetate;Halopredone 17,21-diacetate;17,21-Bis(acetyloxy)-2-bromo-6β,9-difluoro-11β-hydroxypregna-1,4-diene-3,20-dione;17α,21-Bis(acetyloxy)-2-bromo-6β,9-difluoro-11β-hydroxypregna-1,4-diene-3,20-dione;17,21-Bis(acetyloxy)-2-bromo-6beta,9-difluoro-11beta-hydroxypregna-1,4-diene-3,20-dione
CBNumber: CB1902921
Molecular Formula: C25H29BrF2O7
Formula Weight: 559.39
MOL File: 57781-14-3.mol

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2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate) Property

Melting point:: 290-292° (dec)
alpha: D24 -36° (c = 1 in chloroform)
Density: 1.3611 (rough estimate)
refractive index: 1.3760 (estimate)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0002886
Product name: 2-BROMO-6BETA,9-DIFLUORO-11BETA,17,21-TRIHYDROXYPREGNA-1,4-DIENE-3,20-DIONE 17,21-DI(ACETATE)
Purity: 95.00%
Packaging: 5MG
Price: $505.75
Updated: 2021/12/16

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2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate) Chemical Properties,Usage,Production

Originator

Topicon,Pierrel,Italy,1983

Uses

Anti-inflammatory (topical).

Definition

ChEBI: Halopredone acetate is an organic molecular entity.

Manufacturing Process

100 ml of a 70% hydrofluoric acid aqueous solution were cooled to -10°C in a polyethylene flask equipped with electromagnetic stirrer. 10 g of 2-bromo-6β- fluoro-17α,21-dihydroxy-9β, 11β-oxido-pregna-1,4-diene-3,20-dione-17,21- diacetate were added under stirring during 15 minutes. After 0.5 hour the reaction mixture was precipitated in water and ammonia. The solid was collected by filtration, washed with water and dried to a constant weight, giving about 9.5 g of 2-bromo-6β,9α-difluoro-11β,17α,21 -trihydroxypregna- 1,4-diene-3,20-dione-17,21-diacetate.

Therapeutic Function

Topical antiinflammatory

2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate) Preparation Products And Raw materials

Raw materials

Preparation Products

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2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate) Suppliers

China 2 United States 1 Global 3

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

57781-14-3, 2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate)Related Search:

1-BROMO-4-METHYL-3-HEXENE halopredone 1,3-DIACETOXYACETONE 5-BROMO-2-METHYL-2-PENTENE 2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate)

Haloart

halopredone acetate

2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate)

Pregna-1,4-diene-3,20-dione, 17,21-bis(acetyloxy)-2-bromo-6,9-difluoro-11-hydroxy-, (6β,11β)-

THS 201

Topicon

17,21-Bis(acetyloxy)-2-bromo-6β,9-difluoro-11β-hydroxypregna-1,4-diene-3,20-dione

17α,21-Bis(acetyloxy)-2-bromo-6β,9-difluoro-11β-hydroxypregna-1,4-diene-3,20-dione

17,21-Bis(acetyloxy)-2-bromo-6-beta,9-difluoro-11-beta-hydroxypregna-1,4-dien-3,20-dione

17,21-Bis(acetyloxy)-2-bromo-6beta,9-difluoro-11beta-hydroxypregna-1,4-diene-3,20-dione

Ccris 2685

Einecs 260-951-4

Halopredone 17,21-diacetate

Pregna-1,4-diene-3,20-dione, 17,21-bis(acetyloxy)-2-bromo-6,9-difluoro-11-hydroxy-, (6beta,11beta)-

57781-14-3

C25H29BrF2O7